Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis

Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses

(2018) Shankar S. Iyer et al.   CELL

Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis

(2017) A F Citalán-Madrid et al.   Mucosal Immunology

Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer

(2017) Sonia A. Leon-Cabrera et al.   Cancer Immunology Research

Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response

(2017) Asha Jayakumar et al.   NEOPLASIA

The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity

(2016) Xinyang Song et al.   Cellular & Molecular Immunology

Designer matrices for intestinal stem cell and organoid culture

(2016) Nikolce Gjorevski et al.   NATURE

Inflammatory networks underlying colorectal cancer

(2016) Audrey Lasry et al.   NATURE IMMUNOLOGY

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

The differential expression of IL-4 and IL-13 and its impact on type-2 immunity

(2015) Katherine Bao et al.   CYTOKINE

Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation

(2015) Joseph M. Reynolds et al.   IMMUNITY

Stat3

(2014) Jie Han et al.   INFLAMMATORY BOWEL DISEASES

TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis

(2013) Liping Su et al.   GASTROENTEROLOGY

Deletion of Intestinal Epithelial Cell STAT3 Promotes T-Lymphocyte STAT3 Activation and Chronic Colitis Following Acute Dextran Sodium Sulfate Injury in Mice

(2013) Tara A. Willson et al.   INFLAMMATORY BOWEL DISEASES

Myosin light chain kinase: pulling the strings of epithelial tight junction function

(2012) Kevin E. Cunningham et al.   Annals of the New York Academy of Sciences

Myosin Light Chain Kinase Inhibitor Inhibits Dextran Sulfate Sodium-Induced Colitis in Mice

(2012) Xiaochang Liu et al.   DIGESTIVE DISEASES AND SCIENCES

The role of neutrophils during intestinal inflammation

(2012) B M Fournier et al.   Mucosal Immunology

STAT6 activation in ulcerative colitis: A new target for prevention of IL-13-induced colon epithelial cell dysfunction

(2011) Michael J. Rosen et al.   INFLAMMATORY BOWEL DISEASES

Shift from pStat6 to pStat3 Predominance Is Associated with Inflammatory Bowel Disease-Associated Dysplasia

(2011) Elizabeth C. Wick et al.   INFLAMMATORY BOWEL DISEASES

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

Epithelial Tight Junctions in Intestinal Inflammation

(2009) Joerg D. Schulzke et al.   Annals of the New York Academy of Sciences

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis

(2008) Liping Su et al.   GASTROENTEROLOGY

Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies

(2008) Peter Laszlo Lakatos et al.   WORLD JOURNAL OF GASTROENTEROLOGY