Emerging Roles of Energy Metabolism in Ferroptosis Regulation of Tumor Cells
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Title
Emerging Roles of Energy Metabolism in Ferroptosis Regulation of Tumor Cells
Authors
Keywords
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Journal
Advanced Science
Volume 8, Issue 22, Pages 2100997
Publisher
Wiley
Online
2021-10-12
DOI
10.1002/advs.202100997
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Note: Only part of the references are listed.- Nanocatalytic Theranostics with Glutathione Depletion and Enhanced Reactive Oxygen Species Generation for Efficient Cancer Therapy
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- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- (2020) Massimo M. Santoro Cell Metabolism
- The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression
- (2020) Guang Lei et al. CELL RESEARCH
- MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling
- (2020) Divya Venkatesh et al. GENES & DEVELOPMENT
- Energy-stress-mediated AMPK activation inhibits ferroptosis
- (2020) Hyemin Lee et al. NATURE CELL BIOLOGY
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- (2020) Yilong Zou et al. Nature Chemical Biology
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- (2020) Jeonghan Kim et al. SCIENCE
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- (2020) Yongfei Yang et al. Nature Communications
- O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth
- (2020) Hao Nie et al. Nature Communications
- Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer
- (2020) Daiha Shin et al. Redox Biology
- Hepatic Transferrin Plays a Role in Systemic Iron Homeostasis and Liver Ferroptosis
- (2020) Yingying Yu et al. BLOOD
- Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis
- (2020) Xuexian Fang et al. CIRCULATION RESEARCH
- Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
- (2020) Xiaoguang Liu et al. NATURE CELL BIOLOGY
- Targeting apoptosis in cancer therapy
- (2020) Benedito A. Carneiro et al. Nature Reviews Clinical Oncology
- Cysteine depletion induces pancreatic tumor ferroptosis in mice
- (2020) Michael A. Badgley et al. SCIENCE
- xCT Inhibition Increases Sensitivity to Vorinostat in a ROS-Dependent Manner
- (2020) Keiko Miyamoto et al. Cancers
- A Tumor-Targeted Cascade Nanoreactor Based on Metal-Organic-Frameworks for Synergistic Ferroptosis−Starvation Anticancer Therapy
- (2020) Xiuyan Wan et al. ACS Nano
- Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment
- (2020) Zijian Zhou et al. ADVANCED DRUG DELIVERY REVIEWS
- Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
- (2020) Jing Liu et al. CELL RESEARCH
- Dietary Lipids Induce Ferroptosis in Caenorhabditis elegans and Human Cancer Cells
- (2020) Marcos A. Perez et al. DEVELOPMENTAL CELL
- Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
- (2020) Mariluz Soula et al. Nature Chemical Biology
- The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy
- (2020) Yuechen Zhao et al. OncoTargets and Therapy
- Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
- (2020) Kevin Berthenet et al. Cell Reports
- Ferroptosis: machinery and regulation
- (2020) Xin Chen et al. Autophagy
- Functional interplay among thiol-based redox signaling, metabolism, and ferroptosis unveiled by a genetic variant of TP53
- (2020) Julia I-Ju Leu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Myeloid FBW7 deficiency disrupts redox homeostasis and aggravates dietary-induced insulin resistance
- (2020) Cheng Wang et al. Redox Biology
- The Metabolic Underpinnings of Ferroptosis
- (2020) Jiashuo Zheng et al. Cell Metabolism
- Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
- (2020) Bo Yan et al. MOLECULAR CELL
- Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer
- (2020) Ji-Yoon Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis
- (2020) Junmei Yi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
- (2020) Youbo Zhao et al. Cell Reports
- FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells
- (2020) Zeng Ye et al. Redox Biology
- Thioredoxin and Glutaredoxin Systems as Potential Targets for the Development of New Treatments in Friedreich’s Ataxia
- (2020) Marta Seco-Cervera et al. Antioxidants
- Childhood cancer burden: a review of global estimates
- (2019) Nickhill Bhakta et al. LANCET ONCOLOGY
- Critical role of AMPK in redox regulation under glucose starvation
- (2019) Yi Ren et al. Redox Biology
- Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance
- (2019) Ruilong Liu et al. Nature Communications
- Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers
- (2019) Hideaki Ogiwara et al. CANCER CELL
- Glucose Oxidase‐Instructed Multimodal Synergistic Cancer Therapy
- (2019) Lian‐Hua Fu et al. ADVANCED MATERIALS
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
- (2019) Weimin Wang et al. NATURE
- Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells
- (2019) Fei Chen et al. NATURE CELL BIOLOGY
- Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
- (2019) Evijola Llabani et al. Nature Chemistry
- Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
- (2019) Jonathan K. M. Lim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
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- (2019) Lingling Shan et al. ACS Nano
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- (2019) Jiyeon Kim et al. Cell Metabolism
- Recent Progress in Ferroptosis Inducers for Cancer Therapy
- (2019) Chen Liang et al. ADVANCED MATERIALS
- RSL3 induced autophagic death in glioma cells via causing glycolysis dysfunction
- (2019) Xuanzhong Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Tumor angiogenesis: causes, consequences, challenges and opportunities
- (2019) Roberta Lugano et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
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- (2019) Kirill Bersuker et al. NATURE
- The great escape: tumour cell plasticity in resistance to targeted therapy
- (2019) Soufiane Boumahdi et al. NATURE REVIEWS DRUG DISCOVERY
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- (2019) Andrea Ballabio et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2019) Lian-Hua Fu et al. ACS Nano
- A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells
- (2019) Hee Chan Yoo et al. Cell Metabolism
- Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export
- (2019) Caitlin W. Brown et al. DEVELOPMENTAL CELL
- Contents: (Adv. Mater. 12/2018)
- (2018) ADVANCED MATERIALS
- B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies
- (2018) Gang Xiao et al. CELL
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- (2018) Irina Ingold et al. CELL
- miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma
- (2018) Meiying Luo et al. CELL DEATH AND DIFFERENTIATION
- AMPK: Sensing Glucose as well as Cellular Energy Status
- (2018) Sheng-Cai Lin et al. Cell Metabolism
- Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment
- (2018) Lian-Hua Fu et al. CHEMICAL SOCIETY REVIEWS
- Mitochondrial ROS Drive Sudden Cardiac Death and Chronic Proteome Remodeling in Heart FailureNovelty and Significance
- (2018) Swati Dey et al. CIRCULATION RESEARCH
- Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
- (2018) Thomas M. Ashton et al. CLINICAL CANCER RESEARCH
- Regulation of lipid peroxidation and ferroptosis in diverse species
- (2018) Marcus Conrad et al. GENES & DEVELOPMENT
- Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models
- (2018) Michael L Schulte et al. NATURE MEDICINE
- xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression
- (2018) Xiangming Ji et al. ONCOGENE
- Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner
- (2018) Yun-Qian Wang et al. Nature Communications
- Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
- (2018) Dannielle DeWaal et al. Nature Communications
- Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4
- (2018) Li Wang et al. Oncogenesis
- Erythrocyte Membrane Cloaked Metal-Organic Framework Nanoparticle as Biomimetic Nanoreactor for Starvation-Activated Colon Cancer Therapy
- (2018) Lu Zhang et al. ACS Nano
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers
- (2018) Géraldine Gentric et al. Cell Metabolism
- miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma
- (2018) Kexin Zhang et al. MOLECULAR CARCINOGENESIS
- Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
- (2018) Gaojian Lian et al. eLife
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Energy Metabolism of the Osteoblast: Implications for Osteoporosis
- (2017) Wen-Chih Lee et al. ENDOCRINE REVIEWS
- AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance
- (2017) Daniel Garcia et al. MOLECULAR CELL
- Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
- (2017) Matthew J. Hangauer et al. NATURE
- Tumour heterogeneity and resistance to cancer therapies
- (2017) Ibiayi Dagogo-Jack et al. Nature Reviews Clinical Oncology
- Mitochondrial ROS control of cancer
- (2017) María del Pilar Sosa Idelchik et al. SEMINARS IN CANCER BIOLOGY
- The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
- (2017) Chun-Shik Shin et al. Nature Communications
- The emerging role and targetability of the TCA cycle in cancer metabolism
- (2017) Nicole M. Anderson et al. Protein & Cell
- Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells
- (2017) David N. DeHart et al. SLAS Discovery
- Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation
- (2016) Cyril Corbet et al. Cell Metabolism
- Mitochondria and Cancer
- (2016) Wei-Xing Zong et al. MOLECULAR CELL
- ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy
- (2016) Terytty Yang Li et al. MOLECULAR CELL
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Cancer metabolism: a therapeutic perspective
- (2016) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer
- (2016) Geneviève Deblois et al. Nature Communications
- Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function
- (2015) N. V. Rajeshkumar et al. CANCER RESEARCH
- TRAF6-Mediated SM22α K21 Ubiquitination Promotes G6PD Activation and NADPH Production, Contributing to GSH Homeostasis and VSMC Survival In Vitro and In VivoNovelty and Significance
- (2015) Li-Hua Dong et al. CIRCULATION RESEARCH
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Ferroptosis as a p53-mediated activity during tumour suppression
- (2015) Le Jiang et al. NATURE
- 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
- (2015) Ruiting Lin et al. NATURE CELL BIOLOGY
- ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer
- (2015) M van Geldermalsen et al. ONCOGENE
- Metabolic Cancer Biology: Structural-based analysis of cancer as a metabolic disease, new sights and opportunities for disease treatment
- (2015) Ali Masoudi-Nejad et al. SEMINARS IN CANCER BIOLOGY
- The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
- (2014) Anna Stincone et al. BIOLOGICAL REVIEWS
- Genetic Disruption of Lactate/H+ Symporters (MCTs) and Their Subunit CD147/BASIGIN Sensitizes Glycolytic Tumor Cells to Phenformin
- (2014) I. Marchiq et al. CANCER RESEARCH
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Cardiac Mitochondria and Reactive Oxygen Species Generation
- (2014) Yeong-Renn Chen et al. CIRCULATION RESEARCH
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling
- (2013) P. S. Hole et al. BLOOD
- Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
- (2013) Luika A. Timmerman et al. CANCER CELL
- Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib
- (2013) Christophe Louandre et al. INTERNATIONAL JOURNAL OF CANCER
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
- (2012) Sang-Min Jeon et al. NATURE
- Metabolic regulation by SIRT3: implications for tumorigenesis
- (2012) Lydia W.S. Finley et al. TRENDS IN MOLECULAR MEDICINE
- p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
- (2011) Peng Jiang et al. NATURE CELL BIOLOGY
- Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress
- (2010) Rishi Raj Chhipa et al. CELLULAR SIGNALLING
- VDAC, a multi-functional mitochondrial protein regulating cell life and death
- (2010) Varda Shoshan-Barmatz et al. MOLECULAR ASPECTS OF MEDICINE
- The genetic basis of kidney cancer: a metabolic disease
- (2010) W. Marston Linehan et al. Nature Reviews Urology
- Glutathione dysregulation and the etiology and progression of human diseases
- (2009) Nazzareno Ballatori et al. BIOLOGICAL CHEMISTRY
- Adhesion-mediated apoptosis resistance in cancer
- (2009) Mike-Andrew Westhoff et al. DRUG RESISTANCE UPDATES
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
- (2008) Wan Seok Yang et al. CHEMISTRY & BIOLOGY
- Glutathione: Overview of its protective roles, measurement, and biosynthesis
- (2008) Henry Jay Forman et al. MOLECULAR ASPECTS OF MEDICINE
- Mitochondria in cancer cells: what is so special about them?
- (2008) Vladimir Gogvadze et al. TRENDS IN CELL BIOLOGY
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