Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells

(2016) Aaron M. Hosios et al.   DEVELOPMENTAL CELL

Compartmentation of Metabolites in Regulating Epigenomes of Cancer

(2016) Zhiqiang Zhao et al.   MOLECULAR MEDICINE

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

(2015) Lucas B. Sullivan et al.   CELL

Bimolecular Fluorescence Complementation (BiFC) Analysis: Advances and Recent Applications for Genome-Wide Interaction Studies

(2015) Kristi E. Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design

(2014) Brendan J. Hilbert et al.   FEBS LETTERS

Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling

(2013) Alexander V. Zhdanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

(2013) Seung Min Jeong et al.   CANCER CELL

Nicotinamide Adenine Dinucleotide-induced Multimerization of the Co-repressor CtBP1 Relies on a Switching Tryptophan

(2013) Dana L. Madison et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy

(2013) A Garufi et al.   Cell Death & Disease

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Glutamine depletion and glucose depletion trigger growth inhibition via distinctive gene expression reprogramming

(2012) Shuo Qie et al.   CELL CYCLE

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

(2012) Anne Le et al.   Cell Metabolism

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Glutamine: pleiotropic roles in tumor growth and stress resistance

(2011) Naval P. Shanware et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transcriptional down-regulation of Brca1 and E-cadherin by CtBP1 in breast cancer

(2011) Yu Deng et al.   MOLECULAR CARCINOGENESIS

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

(2010) K. E. Wellen et al.   GENES & DEVELOPMENT

Transcriptional regulation of BRCA1 expression by a metabolic switch

(2010) Li-Jun Di et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Glutamine addiction: a new therapeutic target in cancer

(2010) David R. Wise et al.   TRENDS IN BIOCHEMICAL SCIENCES

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

(2009) R J DeBerardinis et al.   ONCOGENE

Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity

(2009) M. R. Kaadige et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE