O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth

Cancer Metabolism Drives a Stromal Regenerative Response

(2019) Simon Schwörer et al.   Cell Metabolism

Structural characterization of the O-GlcNAc cycling enzymes: insights into substrate recognition and catalytic mechanisms

(2019) Cassandra M Joiner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect

(2018) Linchong Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe

(2018) Saar A. M. van der Laarse et al.   FEBS Journal

Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis

(2018) Yajuan Zhang et al.   MOLECULAR CELL

Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication

(2018) Xinjian Li et al.   MOLECULAR CELL

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer

(2018) Mei Yi et al.   Molecular Metabolism

Protein O-GlcNAcylation: emerging mechanisms and functions

(2017) Xiaoyong Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation

(2017) Aneika C. Leney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAcylation destabilizes the active tetrameric PKM2 to promote the Warburg effect

(2017) Yang Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging role and targetability of the TCA cycle in cancer metabolism

(2017) Nicole M. Anderson et al.   Protein & Cell

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis

(2016) Hongli Hu et al.   HEPATOLOGY

O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling

(2016) Christina M. Ferrer et al.   JOURNAL OF MOLECULAR BIOLOGY

Roles of O-GlcNAc in chronic diseases of aging

(2016) Partha S. Banerjee et al.   MOLECULAR ASPECTS OF MEDICINE

Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms

(2016) Y. Qian et al.   MOLECULAR CANCER RESEARCH

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

(2016) Xinjian Li et al.   MOLECULAR CELL

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dysregulated metabolism contributes to oncogenesis

(2015) Matthew D. Hirschey et al.   SEMINARS IN CANCER BIOLOGY

O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth

(2015) Xiongjian Rao et al.   Nature Communications

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1

(2015) Shiwen Wang et al.   PLOS BIOLOGY

Cancer Metabolism and ElevatedO-GlcNAc in Oncogenic Signaling

(2014) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis

(2013) Jennifer A. Groves et al.   CELL STRESS & CHAPERONES

Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization

(2013) Lei Lv et al.   MOLECULAR CELL

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia

(2013) J. Fan et al.   Molecular Systems Biology

O-GlcNAc and the cardiovascular system

(2013) Sujith Dassanayaka et al.   PHARMACOLOGY & THERAPEUTICS

Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

(2013) Taro Hitosugi et al.   Nature Communications

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

(2012) Anne Le et al.   Cell Metabolism

Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism

(2012) W. Yi et al.   SCIENCE

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

(2010) C. Slawson et al.   TRENDS IN BIOCHEMICAL SCIENCES

The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways

(2009) Q. Zeidan et al.   JOURNAL OF CELL SCIENCE