Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Authors
Keywords
-
Journal
NATURE
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2017-10-31
DOI
10.1038/nature24297
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
- (2017) Sydney M. Shaffer et al. NATURE
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer
- (2016) Jong-Lyel Roh et al. CANCER LETTERS
- The cellular origins of drug resistance in cancer
- (2016) Geoffrey R Oxnard NATURE MEDICINE
- Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
- (2016) Aaron N Hata et al. NATURE MEDICINE
- Ferroptosis: Death by Lipid Peroxidation
- (2016) Wan Seok Yang et al. TRENDS IN CELL BIOLOGY
- Ferroptosis as a p53-mediated activity during tumour suppression
- (2015) Le Jiang et al. NATURE
- Binding-induced, turn-on fluorescence of the EGFR/ERBB kinase inhibitor, lapatinib
- (2015) James N. Wilson et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
- (2014) D. Raha et al. CANCER RESEARCH
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Drug resistance to targeted therapies: Déjà vu all over again
- (2014) Floris H. Groenendijk et al. Molecular Oncology
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Epithelial-to-Mesenchymal Transition Rewires the Molecular Path to PI3K-Dependent Proliferation
- (2013) M. B. Salt et al. Cancer Discovery
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain
- (2012) Si-Eun Yoo et al. FREE RADICAL BIOLOGY AND MEDICINE
- MET-Independent Lung Cancer Cells Evading EGFR Kinase Inhibitors Are Therapeutically Susceptible to BH3 Mimetic Agents
- (2011) W. Fan et al. CANCER RESEARCH
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
- (2010) Sreenath V. Sharma et al. CELL
- Chemistry and biochemistry of lipid peroxidation products
- (2010) F. Guéraud et al. FREE RADICAL RESEARCH
- Sterol carrier protein-2 (SCP-2) involvement in cholesterol hydroperoxide cytotoxicity as revealed by SCP-2 inhibitor effects
- (2010) Tamas Kriska et al. JOURNAL OF LIPID RESEARCH
- A systematic review of human antioxidant genes
- (2009) Daniel et al. Frontiers in Bioscience-Landmark
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More