Microglia in Neuroinflammation and Neurodegeneration: From Understanding to Therapy
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Microglia in Neuroinflammation and Neurodegeneration: From Understanding to Therapy
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 15, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-10-17
DOI
10.3389/fnins.2021.742065
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
- (2021) Emma Gerrits et al. ACTA NEUROPATHOLOGICA
- Heritability Enrichment Implicates Microglia in Parkinson's Disease Pathogenesis
- (2021) Maren Stolp Andersen et al. ANNALS OF NEUROLOGY
- Partial microglial depletion is associated with impaired hippocampal synaptic and cognitive function in young and aged rats
- (2021) Brittney Yegla et al. GLIA
- Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
- (2021) Shahar Alon et al. SCIENCE
- Galectin-3: a key player in microglia-mediated neuroinflammation and Alzheimer's disease
- (2021) Yinyin Tan et al. Cell and Bioscience
- Microglial Nox2 Plays a Key Role in the Pathogenesis of Experimental Autoimmune Encephalomyelitis
- (2021) Chih-Fen Hu et al. Frontiers in Immunology
- Further Characterization of Intrastriatal Lipopolysaccharide Model of Parkinson’s Disease in C57BL/6 Mice
- (2021) Isaac Deng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
- (2021) Deepti Lall et al. NEURON
- Brain Parenchymal and Extraparenchymal Macrophages in Development, Homeostasis, and Disease
- (2020) Simone Brioschi et al. JOURNAL OF IMMUNOLOGY
- Choosing a Parkinson Disease Treatment
- (2020) Melissa J. Armstrong et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease
- (2020) Shun-Fat Lau et al. Cell Reports
- Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model
- (2020) Shoutang Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- To Kill a Microglia: A Case for CSF1R Inhibitors
- (2020) Kim N. Green et al. TRENDS IN IMMUNOLOGY
- Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis
- (2020) Oriol Dols-Icardo et al. Neurology-Neuroimmunology & Neuroinflammation
- Evaluation of serum galectin-3 levels at Alzheimer patients by stages: a preliminary report
- (2020) Tamer Yazar et al. ACTA NEUROLOGICA BELGICA
- APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease
- (2020) Aivi T. Nguyen et al. ACTA NEUROPATHOLOGICA
- T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson’s disease
- (2020) Meena S. Subbarayan et al. Journal of Neuroinflammation
- ALS Genetics: Gains, Losses, and Implications for Future Therapies
- (2020) Garam Kim et al. NEURON
- CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages
- (2020) Fengyang Lei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translating genetic risk of Alzheimer’s disease into mechanistic insight and drug targets
- (2020) Annerieke Sierksma et al. SCIENCE
- A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
- (2020) Devika Agarwal et al. Nature Communications
- Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis
- (2020) Chotima Böttcher et al. Acta Neuropathologica Communications
- Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
- (2020) Marta Olah et al. Nature Communications
- CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE
- (2019) Agnieszka Wlodarczyk et al. Frontiers in Cellular Neuroscience
- Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
- (2019) Takahiro Masuda et al. NATURE
- Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
- (2019) Antonio Boza-Serrano et al. ACTA NEUROPATHOLOGICA
- Microglia suppress the secondary progression of autoimmune encephalomyelitis
- (2019) Shogo Tanabe et al. GLIA
- Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study
- (2019) Kimberly D. van der Willik et al. Journal of Neuroinflammation
- Single-cell transcriptomic analysis of Alzheimer’s disease
- (2019) Hansruedi Mathys et al. NATURE
- Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis
- (2019) Silas Maniatis et al. SCIENCE
- Central nervous system regeneration is driven by microglia necroptosis and repopulation
- (2019) Amy F. Lloyd et al. NATURE NEUROSCIENCE
- Communication of CD 8 + T cells with mononuclear phagocytes in multiple sclerosis
- (2019) Matea Konjevic Sabolek et al. Annals of Clinical and Translational Neurology
- Microglia and the Aging Brain: Are Senescent Microglia the Key to Neurodegeneration?
- (2019) Dafina M. Angelova et al. JOURNAL OF NEUROCHEMISTRY
- Paraquat and Parkinson’s disease: a systematic review and meta-analysis of observational studies
- (2019) Carolina Vaccari et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
- (2019) SCIENCE
- A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
- (2019) Alexandra Grubman et al. NATURE NEUROSCIENCE
- Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
- (2019) Oliver H. Tam et al. Cell Reports
- Convergence between Microglia and Peripheral Macrophages Phenotype during Development and Neuroinflammation
- (2019) Francesca Grassivaro et al. JOURNAL OF NEUROSCIENCE
- B-cell Therapy for Multiple Sclerosis: Entering an era
- (2018) Ariele L. Greenfield et al. ANNALS OF NEUROLOGY
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States
- (2018) Mark P. Mattson et al. Cell Metabolism
- Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery
- (2018) Jillian C. Nissen et al. EXPERIMENTAL NEUROLOGY
- Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
- (2018) François Mouton-Liger et al. GLIA
- Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
- (2018) Krista J. Spiller et al. NATURE NEUROSCIENCE
- Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models
- (2018) Bahareh Ajami et al. NATURE NEUROSCIENCE
- Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain
- (2018) Diego Mastroeni et al. NEUROBIOLOGY OF AGING
- Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
- (2018) C.Y. Daniel Lee et al. NEURON
- The Elusive P2X7 Macropore
- (2018) Francesco Di Virgilio et al. TRENDS IN CELL BIOLOGY
- Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis
- (2018) Chiara Rossi et al. Cell Death & Disease
- Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex
- (2018) Thomas E. Chan et al. Frontiers in Aging Neuroscience
- Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945
- (2018) Nicolau Beckmann et al. Acta Neuropathologica Communications
- Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis
- (2018) Robert J. Fox et al. NEW ENGLAND JOURNAL OF MEDICINE
- The genetic landscape of Parkinson's disease
- (2018) A. Lunati et al. REVUE NEUROLOGIQUE
- Neuropathology and cognitive performance in self-reported cognitively healthy centenarians
- (2018) Andrea B. Ganz et al. Acta Neuropathologica Communications
- TREM2 triggers microglial density and age‐related neuronal loss
- (2018) Bettina Linnartz‐Gerlach et al. GLIA
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- (2018) E. Ray Dorsey et al. LANCET NEUROLOGY
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
- (2018) Richard Gordon et al. Science Translational Medicine
- Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review)
- (2017) Rui Dong et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model
- (2017) Avi Fellner et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microglia in Alzheimer’s disease
- (2017) David V. Hansen et al. JOURNAL OF CELL BIOLOGY
- New insights into the burden and costs of multiple sclerosis in Europe
- (2017) Gisela Kobelt et al. Multiple Sclerosis Journal
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
- (2017) Rebecca Sims et al. NATURE GENETICS
- Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
- (2017) Thais F Galatro et al. NATURE NEUROSCIENCE
- Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
- (2017) Petra Füger et al. NATURE NEUROSCIENCE
- A new fate mapping system reveals context-dependent random or clonal expansion of microglia
- (2017) Tuan Leng Tay et al. NATURE NEUROSCIENCE
- Effects of aging on functional and structural brain connectivity
- (2017) Jessica S. Damoiseaux NEUROIMAGE
- Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging
- (2017) Lilach Soreq et al. Cell Reports
- The Lifespan and Turnover of Microglia in the Human Brain
- (2017) Pedro Réu et al. Cell Reports
- Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain
- (2017) Katharine Askew et al. Cell Reports
- New insights into the burden and costs of multiple sclerosis in Europe
- (2017) Gisela Kobelt et al. Multiple Sclerosis Journal
- Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS
- (2017) Anna Maria D’Erchia et al. Scientific Reports
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1
- (2016) M. Gravel et al. JOURNAL OF NEUROSCIENCE
- The epidemiology of Parkinson's disease: risk factors and prevention
- (2016) Alberto Ascherio et al. LANCET NEUROLOGY
- Origin, fate and dynamics of macrophages at central nervous system interfaces
- (2016) Tobias Goldmann et al. NATURE IMMUNOLOGY
- Age-related myelin degradation burdens the clearance function of microglia during aging
- (2016) Shima Safaiyan et al. NATURE NEUROSCIENCE
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- TYROBP genetic variants in early-onset Alzheimer's disease
- (2016) Cyril Pottier et al. NEUROBIOLOGY OF AGING
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- Epidemiology of multiple sclerosis
- (2016) E. Leray et al. REVUE NEUROLOGIQUE
- Microglia development follows a stepwise program to regulate brain homeostasis
- (2016) O. Matcovitch-Natan et al. SCIENCE
- Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke
- (2016) Gergely Szalay et al. Nature Communications
- CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves
- (2016) Anna Martínez-Muriana et al. Scientific Reports
- Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset
- (2016) Juan D. Rodriguez-Callejas et al. Frontiers in Aging Neuroscience
- C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers
- (2016) Patrizia Rizzu et al. Acta Neuropathologica Communications
- Positive Association of the Cathepsin D Ala224Val Gene Polymorphism With the Risk of Alzheimer's Disease
- (2015) César A. Paz-y-Miño et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson’s disease
- (2015) Aurelija Jucaite et al. BRAIN
- TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
- (2015) Taylor R. Jay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis
- (2015) Jia Y Lee et al. Journal of Neuroinflammation
- Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
- (2015) Nikenza Viceconte et al. Journal of Neuroinflammation
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype
- (2015) Hongshan Chen et al. MOLECULAR CELL
- Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
- (2015) Yu Tang et al. MOLECULAR NEUROBIOLOGY
- Depletion of microglia and inhibition of exosome synthesis halt tau propagation
- (2015) Hirohide Asai et al. NATURE NEUROSCIENCE
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
- (2015) Stefano G. Daniele et al. Science Signaling
- Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems
- (2015) Ari Waisman et al. TRENDS IN IMMUNOLOGY
- A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology
- (2015) Mar Matarin et al. Cell Reports
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
- (2015) Stefano G. Daniele et al. Science Signaling
- IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity
- (2015) Magdalena Kocur et al. Acta Neuropathologica Communications
- Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis
- (2014) S. Apolloni et al. Disease Models & Mechanisms
- IL-4 Signaling Drives a Unique Arginase+/IL-1 + Microglia Phenotype and Recruits Macrophages to the Inflammatory CNS: Consequences of Age-Related Deficits in IL-4R after Traumatic Spinal Cord Injury
- (2014) A. M. Fenn et al. JOURNAL OF NEUROSCIENCE
- Transient Activation of p53 in G2 Phase Is Sufficient to Induce Senescence
- (2014) Lenno Krenning et al. MOLECULAR CELL
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: An in vivo [(11)C](R)-PK11195-PET pilot study
- (2014) Paolo Giannetti et al. NEUROBIOLOGY OF DISEASE
- Defining the clinical course of multiple sclerosis: The 2013 revisions
- (2014) F. D. Lublin et al. NEUROLOGY
- Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
- (2014) Ashley E. Frakes et al. NEURON
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite
- (2014) Joel A. Krauser et al. XENOBIOTICA
- Experimental autoimmune encephalomyelitis is a good model of multiple sclerosis if used wisely
- (2014) David Baker et al. Multiple Sclerosis and Related Disorders
- TREM2 and the neuroimmunology of Alzheimer's disease
- (2013) Suzanne E. Hickman et al. BIOCHEMICAL PHARMACOLOGY
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Clinical and genetic heterogeneity of amyotrophic lateral sclerosis
- (2013) M Sabatelli et al. CLINICAL GENETICS
- Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
- (2013) S. Apolloni et al. HUMAN MOLECULAR GENETICS
- Pathology and disease mechanisms in different stages of multiple sclerosis
- (2013) Hans Lassmann JOURNAL OF THE NEUROLOGICAL SCIENCES
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
- (2013) Tobias Goldmann et al. NATURE NEUROSCIENCE
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- Neuroinflammation in healthy aging: A PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [18F]-FEPPA
- (2013) I. Suridjan et al. NEUROIMAGE
- Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies
- (2013) Gaia Codolo et al. PLoS One
- Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
- (2013) J.-F. Trempe et al. SCIENCE
- A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
- (2013) Isaac M. Chiu et al. Cell Reports
- Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
- (2012) Bing Liao et al. EXPERIMENTAL NEUROLOGY
- LRRK2 Inhibition Attenuates Microglial Inflammatory Responses
- (2012) M. S. Moehle et al. JOURNAL OF NEUROSCIENCE
- Genetic variation in galectin-3 gene associates with cognitive function at old age
- (2012) Stella Trompet et al. NEUROBIOLOGY OF AGING
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Non-Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Inflammatory Cytokines in Serum
- (2012) Daniel Lindqvist et al. PLoS One
- Checklist for reporting and reviewing studies of experimental animal models of multiple sclerosis and related disorders
- (2012) Sandra Amor et al. Multiple Sclerosis and Related Disorders
- Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
- (2011) Cris S Constantinescu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis
- (2011) Eveliina Pollari et al. Journal of Neuroinflammation
- The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease
- (2011) Sergey Kalinin et al. NEUROBIOLOGY OF AGING
- Age and disease related changes in the translocator protein (TSPO) system in the human brain: Positron emission tomography measurements with [11C]vinpocetine
- (2011) Balázs Gulyás et al. NEUROIMAGE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease
- (2011) C Barcia et al. Cell Death & Disease
- Age-related alterations in the dynamic behavior of microglia
- (2010) Mausam R. Damani et al. AGING CELL
- Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain
- (2010) Kai Diederich et al. HIPPOCAMPUS
- CSF chemokine alterations related to the clinical course of amyotrophic lateral sclerosis
- (2010) Takahisa Tateishi et al. JOURNAL OF NEUROIMMUNOLOGY
- Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S
- (2010) X. Li et al. JOURNAL OF NEUROSCIENCE
- Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study
- (2010) Hannu Laaksovirta et al. LANCET NEUROLOGY
- Multiple sclerosis: risk factors, prodromes, and potential causal pathways
- (2010) Sreeram V Ramagopalan et al. LANCET NEUROLOGY
- DAMPening Inflammation by Modulating TLR Signalling
- (2010) A. M. Piccinini et al. MEDIATORS OF INFLAMMATION
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phospho-eIF2α Level Is Important for Determining Abilities of BACE1 Reduction to Rescue Cholinergic Neurodegeneration and Memory Defects in 5XFAD Mice
- (2010) Latha Devi et al. PLoS One
- Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease
- (2010) Lesley Jones et al. PLoS One
- Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
- (2010) Y. Cho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of -synuclein, and apoptotic cell death in aged mice
- (2010) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- The relation between inflammation and neurodegeneration in multiple sclerosis brains
- (2009) Josa M. Frischer et al. BRAIN
- Anti-melanin antibodies are increased in sera in Parkinson's disease
- (2009) K.L. Double et al. EXPERIMENTAL NEUROLOGY
- Extracellular mutant SOD1 induces microglial-mediated motoneuron injury
- (2009) Weihua Zhao et al. GLIA
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Proinflammatory Action of Microglial P2 Receptors Is Enhanced in SOD1 Models for Amyotrophic Lateral Sclerosis
- (2009) N. D'Ambrosi et al. JOURNAL OF IMMUNOLOGY
- Multiple sclerosis therapeutics: Unexpected outcomes clouding undisputed successes
- (2009) H. Wiendl et al. NEUROLOGY
- Molecular genetics of Alzheimer's disease: An update
- (2008) Nathalie Brouwers et al. ANNALS OF MEDICINE
- Multiple Sclerosis: An Immune or Neurodegenerative Disorder?
- (2008) Bruce D. Trapp et al. Annual Review of Neuroscience
- The neuroglial population in the primary visual cortex of the aging rhesus monkey
- (2008) Alan Peters et al. GLIA
- Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
- (2008) Vanessa Brochard et al. JOURNAL OF CLINICAL INVESTIGATION
- Ablation of Proliferating Microglia Does Not Affect Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis Caused by Mutant Superoxide Dismutase
- (2008) G. Gowing et al. JOURNAL OF NEUROSCIENCE
- Synuclein activates microglia in a model of Parkinson's disease
- (2007) Xiaomin Su et al. NEUROBIOLOGY OF AGING
- Neocortical glial cell numbers in human brains
- (2007) D.P. Pelvig et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More