A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

(2012) Monika Julia Wolf et al.   CANCER CELL

TAK1 Negatively Regulates NF-κB and p38 MAP Kinase Activation in Gr-1+CD11b+ Neutrophils

(2012) Adebusola Alagbala Ajibade et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: The role of BDNF/TrkB/Erk1/2 signaling in neuroprotection

(2012) Fahim Atif et al.   NEUROPHARMACOLOGY

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function

(2012) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

In vivo structure/function and expression analysis of the CX3C chemokine fractalkine

(2011) K.-W. Kim et al.   BLOOD

Nano-electrospray tandem mass spectrometric analysis of the acetylation state of histones H3 and H4 in stationary phase in Saccharomyces cerevisiae

(2011) Mzwanele Ngubo et al.   BMC BIOCHEMISTRY

IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

(2011) Jenni Raasch et al.   BRAIN

Genetic approaches to study glial cells in the rodent brain

(2011) Frank W. Pfrieger et al.   GLIA

Transforming Growth Factor-β-activated Kinase 1 Regulates Natural Killer Cell-mediated Cytotoxicity and Cytokine Production

(2011) Kamalakannan Rajasekaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anergic CD8+ T Lymphocytes Have Impaired NF- B Activation with Defects in p65 Phosphorylation and Acetylation

(2011) P. E. Clavijo et al.   JOURNAL OF IMMUNOLOGY

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

(2011) A. Mildner et al.   JOURNAL OF NEUROSCIENCE

Cytosolic RIG-I–like helicases act as negative regulators of sterile inflammation in the CNS

(2011) Angela Dann et al.   NATURE NEUROSCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

TAK1 Suppresses a NEMO-Dependent but NF-κB-Independent Pathway to Liver Cancer

(2010) Kira Bettermann et al.   CANCER CELL

Microglia in the CNS: Immigrants from another world

(2010) Marco Prinz et al.   GLIA

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Quantitative evaluation of signaling events in Drosophila S2 cells

(2009) David Bond et al.   BIOLOGICAL PROCEDURES ONLINE

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

TNFR signaling: ubiquitin-conjugated TRAFfic signals control stop-and-go for MAPK signaling complexes

(2009) Michael Karin et al.   IMMUNOLOGICAL REVIEWS

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

(2008) Minghui Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Murine Microglial Cells Produce and Respond to Interleukin-18

(2003) Marco Prinz et al.   JOURNAL OF NEUROCHEMISTRY