Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS

Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease

(2016) Lan Lin et al.   HUMAN MOLECULAR GENETICS

REDIportal: a comprehensive database of A-to-I RNA editing events in humans

(2016) Ernesto Picardi et al.   NUCLEIC ACIDS RESEARCH

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord

(2016) David G. Brohawn et al.   PLoS One

The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins

(2015) Maria Grazia Mola et al.   GLIA

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

(2015) Mercedes Prudencio et al.   NATURE NEUROSCIENCE

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Profiling RNA editing in human tissues: towards the inosinome Atlas

(2015) Ernesto Picardi et al.   Scientific Reports

GO-PCA: An Unsupervised Method to Explore Gene Expression Data Using Prior Knowledge

(2015) Florian Wagner   PLoS One

Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis

(2014) Wenzhi Tan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Identification of a Point Mutation Impairing the Binding between Aquaporin-4 and Neuromyelitis Optica Autoantibodies

(2014) Francesco Pisani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA miR-124 Controls the Choice between Neuronal and Astrocyte Differentiation by Fine-tuning Ezh2 Expression

(2014) Wen Hao Neo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis

(2014) Orhan Tansel Korkmaz et al.   NEUROSCIENCE LETTERS

Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses

(2014) Tatsuya Mishima et al.   PLoS One

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

REDItools: high-throughput RNA editing detection made easy

(2013) Ernesto Picardi et al.   BIOINFORMATICS

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

(2013) Joseph M Dhahbi et al.   BMC GENOMICS

miR-219 Regulates Neural Precursor Differentiation by Direct Inhibition of Apical Par Polarity Proteins

(2013) Laura I. Hudish et al.   DEVELOPMENTAL CELL

Reduced SNAP-25 alters short-term plasticity at developing glutamatergic synapses

(2013) Flavia Antonucci et al.   EMBO REPORTS

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination

(2013) Aya D. Pusic et al.   GLIA

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

(2013) Erica D. Koval et al.   HUMAN MOLECULAR GENETICS

Specific Induction of Akt3 in Spinal Cord Motor Neurons is Neuroprotective in a Mouse Model of Familial Amyotrophic Lateral Sclerosis

(2013) Marco Peviani et al.   MOLECULAR NEUROBIOLOGY

State of play in amyotrophic lateral sclerosis genetics

(2013) Alan E Renton et al.   NATURE NEUROSCIENCE

Neuroprotective effects of NGF, BDNF, NT-3 and GDNF on axotomized extraocular motoneurons in neonatal rats

(2013) S. Morcuende et al.   NEUROSCIENCE

miR-127 Regulates Cell Proliferation and Senescence by Targeting BCL6

(2013) Jingwen Chen et al.   PLoS One

Intricate interplay between astrocytes and motor neurons in ALS

(2013) H. P. Phatnani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigating cell death mechanisms in amyotrophic lateral sclerosis using transcriptomics

(2013) Paul R. Heath et al.   Frontiers in Cellular Neuroscience

Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation

(2013) C Parisi et al.   Cell Death & Disease

FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD

(2013) Yusuke Fujioka et al.   Scientific Reports

Altered microRNA expression profile in amyotrophic lateral sclerosis: a role in the regulation of NFL mRNA levels

(2013) Danae Campos-Melo et al.   Molecular Brain

Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases

(2012) J. E. Vance   Disease Models & Mechanisms

Syntaxin-1 N-peptide and Habc-domain perform distinct essential functions in synaptic vesicle fusion

(2012) Peng Zhou et al.   EMBO JOURNAL

MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2

(2012) Yi Yang et al.   FEBS LETTERS

Systematic identification of edited microRNAs in the human brain

(2012) S. Alon et al.   GENOME RESEARCH

ALSoD: A user-friendly online bioinformatics tool for amyotrophic lateral sclerosis genetics

(2012) Olubunmi Abel et al.   HUMAN MUTATION

MiR-410 regulates MET to influence the proliferation and invasion of glioma

(2012) Lingchao Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Gene expression profiling in human neurodegenerative disease

(2012) Johnathan Cooper-Knock et al.   Nature Reviews Neurology

Activation of Transforming Growth Factor-β/Smad Signaling Reduces Aggregate Formation of Mislocalized TAR DNA-Binding Protein-43

(2012) Masataka Nakamura et al.   Neurodegenerative Diseases

DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways

(2012) Ioannis S. Vlachos et al.   NUCLEIC ACIDS RESEARCH

MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data

(2012) Shihao Shen et al.   NUCLEIC ACIDS RESEARCH

CSPα knockout causes neurodegeneration by impairing SNAP-25 function

(2011) Manu Sharma et al.   EMBO JOURNAL

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   Nature Reviews Neurology

Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene

(2011) Rebecca L. Skalsky et al.   PLoS One

MicroRNA regulation of homeostatic synaptic plasticity

(2011) J. E. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PI3K/Akt/mTOR signaling regulates glutamate transporter 1 in astrocytes

(2010) Xiaofeng Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous SNAP-25 Regulates Native Voltage-gated Calcium Channels in Glutamatergic Neurons

(2010) Steven B. Condliffe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2

(2010) T. Hideyama et al.   JOURNAL OF NEUROSCIENCE

miRNA malfunction causes spinal motor neuron disease

(2010) S. Haramati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients

(2009) Christiaan GJ Saris et al.   BMC GENOMICS

Sporadic ALS has compartment-specific aberrant exon splicing and altered cell–matrix adhesion biology

(2009) Stuart J. Rabin et al.   HUMAN MOLECULAR GENETICS

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Axon guidance proteins: Novel therapeutic targets for ALS?

(2009) Ewoud R.E. Schmidt et al.   PROGRESS IN NEUROBIOLOGY

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

(2009) C. Cole et al.   RNA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE