Molecular mechanisms and consequences of mitochondrial permeability transition
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanisms and consequences of mitochondrial permeability transition
Authors
Keywords
-
Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-12-08
DOI
10.1038/s41580-021-00433-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- VDAC Regulation of Mitochondrial Calcium Flux: From Channel Biophysics to Disease
- (2021) William M. Rosencrans et al. CELL CALCIUM
- Cyclophilin D‐dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia
- (2021) Balazs Veres et al. FEBS Open Bio
- A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients
- (2021) Giampaolo Morciano et al. Cell Reports
- The f subunit of human ATP synthase is essential for normal mitochondrial morphology and permeability transition
- (2021) Chiara Galber et al. Cell Reports
- Alisporivir Improves Mitochondrial Function in Skeletal Muscle of mdx Mice but Suppresses Mitochondrial Dynamics and Biogenesis
- (2021) Mikhail V. Dubinin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase
- (2021) Andrea Carrer et al. Nature Communications
- Role of Mitochondrial Calcium and the Permeability Transition Pore in Regulating Cell Death
- (2020) Tyler M. Bauer et al. CIRCULATION RESEARCH
- Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST‐segment elevation myocardial infarction
- (2020) Hans Erik Bøtker et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The cell biology of mitochondrial membrane dynamics
- (2020) Marta Giacomello et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
- (2020) Helmut Sies et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inhibition of the mitochondrial permeability transition improves bone fracture repair
- (2020) Brianna H. Shares et al. BONE
- Hematopoietic Stem Cell Metabolism during Development and Aging
- (2020) Ayako Nakamura-Ishizu et al. DEVELOPMENTAL CELL
- Mitochondrial ion channels as targets for cardioprotection
- (2020) Derek J. Hausenloy et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology
- (2020) Massimo Bonora et al. Biomolecules
- TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
- (2020) Chien-Hsiung Yu et al. CELL
- TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model
- (2020) Frank Zamudio et al. Journal of Neuroinflammation
- Cryo-EM structure of the entire mammalian F-type ATP synthase
- (2020) Gergely Pinke et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mitochondrial F-ATP synthase as the permeability transition pore
- (2020) Christoph Gerle PHARMACOLOGICAL RESEARCH
- Structure of the dimeric ATP synthase from bovine mitochondria
- (2020) Tobias E. Spikes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion
- (2020) Stephen Hurst et al. Cell Death & Disease
- The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore
- (2020) Michela Carraro et al. Cell Reports
- ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore
- (2019) Maria A. Neginskaya et al. Cell Reports
- Transport of Proteins into Mitochondria
- (2019) Katja G. Hansen et al. PROTEIN JOURNAL
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension
- (2019) Ben Zhou et al. CELL
- Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation
- (2019) Brittany L. Baechler et al. Autophagy
- Dynamics of the mitochondrial permeability transition pore: Transient and permanent opening events
- (2019) Liron Boyman et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- SPG7 targets the m-AAA protease complex to process MCU for uniporter assembly, Ca2+ influx, and regulation of mPTP opening
- (2019) Stephen Hurst et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Mitochondrial Permeability Transition in Mitochondrial Disorders
- (2019) Justina Šileikytė et al. Oxidative Medicine and Cellular Longevity
- Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia–reperfusion injury
- (2019) Mathieu Panel et al. GASTROENTEROLOGY
- Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI
- (2019) Shrikant Ramesh Mulay et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Persistence of the permeability transition pore in human mitochondria devoid of an assembled ATP synthase
- (2019) Joe Carroll et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Ca 2+ ‐activated F 1 F O ‐ATPase hydrolyzes ATP and promotes the permeability transition pore
- (2019) Cristina Algieri et al. Annals of the New York Academy of Sciences
- Parkin Regulates Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury by Targeting Cyclophilin-D
- (2019) Teng Sun et al. ANTIOXIDANTS & REDOX SIGNALING
- TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit
- (2019) Francisco J. Roca et al. CELL
- Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD
- (2019) Jason Karch et al. Science Advances
- NAD+ in Brain Aging and Neurodegenerative Disorders
- (2019) Sofie Lautrup et al. Cell Metabolism
- Comparison of multiple doses of cyclosporine A on germ cell apoptosis and epididymal sperm parameters after testicular ischemia/reperfusion in rats
- (2019) Iraj Yazdani et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore
- (2019) Andrea Urbani et al. Nature Communications
- Mitochondrial Perturbations Couple mTORC2 to Autophagy in C. elegans
- (2019) Helena Aspernig et al. Cell Reports
- Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation
- (2019) Gesa L. Tiemeier et al. Stem Cell Reports
- Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
- (2019) Vaishali Aggarwal et al. Biomolecules
- A novel class of cardioprotective small-molecule PTP inhibitors
- (2019) Salvatore Antonucci et al. PHARMACOLOGICAL RESEARCH
- Over-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia–reperfusion
- (2018) Hannah J Whittington et al. CARDIOVASCULAR RESEARCH
- Calcium and regulation of the mitochondrial permeability transition
- (2018) Valentina Giorgio et al. CELL CALCIUM
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Collagen VII deficient mice show morphologic and histologic corneal changes that phenotypically mimic human dystrophic epidermolysis bullosa of the eye
- (2018) Vicki M. Chen et al. EXPERIMENTAL EYE RESEARCH
- Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis
- (2018) Xiaolei Wang et al. HEPATOLOGY
- Glycogen synthase kinase-3β opens mitochondrial permeability transition pore through mitochondrial hexokinase II dissociation
- (2018) Takamitsu Tanaka et al. Journal of Physiological Sciences
- Selective induction of cancer cell death by VDAC1-based peptides and their potential use in cancer therapy
- (2018) Anna Shteinfer-Kuzmine et al. Molecular Oncology
- Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
- (2018) Krista J. Spiller et al. NATURE NEUROSCIENCE
- Autophagy as a promoter of longevity: insights from model organisms
- (2018) Malene Hansen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
- (2018) Kate McArthur et al. SCIENCE
- Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming
- (2018) Zhongfu Ying et al. Cell Metabolism
- Metabolism as master of hematopoietic stem cell fate
- (2018) Kyoko Ito et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal
- (2018) Lishu Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction
- (2018) Giampaolo Morciano et al. JOURNAL OF MEDICINAL CHEMISTRY
- Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice
- (2018) Álvaro F. Fernández et al. NATURE
- Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
- (2018) Konstantinos Palikaras et al. NATURE CELL BIOLOGY
- The machineries, regulation and cellular functions of mitochondrial calcium
- (2018) Carlotta Giorgi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cyclophilin D deficiency protects against the development of mitochondrial ROS and cellular inflammation in aorta
- (2018) Xiaojing Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- OSCP subunit of mitochondrial ATP synthase: role in regulation of enzyme function and of its transition to a pore
- (2018) Valentina Giorgio et al. BRITISH JOURNAL OF PHARMACOLOGY
- Akt‐mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth
- (2018) Saverio Marchi et al. EMBO JOURNAL
- Hexokinase II–derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cells
- (2017) Abiy D. Woldetsadik et al. FASEB JOURNAL
- Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia
- (2017) María M. Leal-Lasarte et al. FASEB JOURNAL
- Mitochondrial PKC-ε deficiency promotes I/R-mediated myocardial injury via GSK3β-dependent mitochondrial permeability transition pore opening
- (2017) Shijun Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice
- (2017) Viktoria Vereczki et al. MITOCHONDRION
- BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
- (2017) Angela Bononi et al. NATURE
- The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability
- (2017) Timothy S. Luongo et al. NATURE
- Preventing permeability transition pore opening increases mitochondrial maturation, myocyte differentiation and cardiac function in the neonatal mouse heart
- (2017) Jayson V. Lingan et al. PEDIATRIC RESEARCH
- A Mechanism Study Underlying the Protective Effects of Cyclosporine-A on Lung Ischemia-Reperfusion Injury
- (2017) Jian''an Li et al. PHARMACOLOGY
- Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase
- (2017) Jiuya He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis
- (2017) Rhianna C. Laker et al. PLoS One
- Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity
- (2016) A. P. Richardson et al. BIOCHEMICAL JOURNAL
- Molecular structure and pathophysiological roles of the Mitochondrial Calcium Uniporter
- (2016) Cristina Mammucari et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca 2+ signaling
- (2016) Mart Bittremieux et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization
- (2016) Wen Yang et al. CELL
- Mitochondrial cAMP signaling
- (2016) Fan Zhang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Normalization of NAD+Redox Balance as a Therapy for Heart FailureClinical Perspective
- (2016) Chi Fung Lee et al. CIRCULATION
- Mitochondria in pluripotent stem cells: stemness regulators and disease targets
- (2016) Clifford DL Folmes et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Skeletal muscle ischemia-reperfusion injury and cyclosporine A in the aging rat
- (2016) Julien Pottecher et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition
- (2016) Weihua Yu et al. International Journal of Biological Sciences
- Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice
- (2016) Esha Gauba et al. JOURNAL OF ALZHEIMERS DISEASE
- Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis
- (2016) Emma R. Shore et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems
- (2016) Ivan Lebedev et al. JOURNAL OF MOLECULAR BIOLOGY
- Mitophagy plays a central role in mitochondrial ageing
- (2016) Alan Diot et al. MAMMALIAN GENOME
- The Mitochondrial Basis of Aging
- (2016) Nuo Sun et al. MOLECULAR CELL
- Autophagy maintains stemness by preventing senescence
- (2016) Laura García-Prat et al. NATURE
- The Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP Synthase
- (2016) Nina Kaludercic et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial permeability transition pore: a promising target for the treatment of Parkinson’s disease
- (2016) Md Zeeshan Rasheed et al. PROTOPLASMA
- Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction
- (2016) Koteswara Rao Valasani et al. ACS Medicinal Chemistry Letters
- Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
- (2016) Angela V. Hafner et al. Aging-US
- Lysosomal calcium regulates autophagy
- (2015) Diego L Medina et al. Autophagy
- Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages
- (2015) Janos Priber et al. Biochemistry and Cell Biology
- The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury
- (2015) L Gomez et al. CELL DEATH AND DIFFERENTIATION
- Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts
- (2015) Moshi Song et al. Cell Metabolism
- Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis
- (2015) Justin Warne et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Essential role for autophagy in life span extension
- (2015) Frank Madeo et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D
- (2015) T. Bochaton et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The mitochondrial permeability transition: A current perspective on its identity and role in ischaemia/reperfusion injury
- (2015) Andrew P. Halestrap et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
- (2015) Jagadish C. Ghosh et al. JNCI-Journal of the National Cancer Institute
- SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore
- (2015) Santhanam Shanmughapriya et al. MOLECULAR CELL
- Mitochondria: a therapeutic target in acute kidney injury
- (2015) Yu Ishimoto et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Erratum: Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
- (2015) M Bonora et al. ONCOGENE
- p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner
- (2015) Carlotta Giorgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
- (2015) G. Gong et al. SCIENCE
- Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism
- (2015) Michele Tavecchio et al. Scientific Reports
- The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition
- (2015) Timothy S. Luongo et al. Cell Reports
- Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
- (2015) Jagadish C. Ghosh et al. JNCI-Journal of the National Cancer Institute
- Reperfusion injury and reactive oxygen species: The evolution of a concept
- (2015) D. Neil Granger et al. Redox Biology
- Mitochondrial Vulnerability and Increased Susceptibility to Nutrient-Induced Cytotoxicity in Fibroblasts from Leigh Syndrome French Canadian Patients
- (2015) Yan Burelle et al. PLoS One
- Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling
- (2015) Carlotta Giorgi et al. Oncotarget
- HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore
- (2014) Sang-Ging Ong et al. CARDIOVASCULAR RESEARCH
- Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
- (2014) R. Allam et al. EMBO REPORTS
- Regulation of the Mitochondrial Permeability Transition Pore by the Outer Membrane Does Not Involve the Peripheral Benzodiazepine Receptor (Translocator Protein of 18 kDa (TSPO))
- (2014) Justina Šileikytė et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Translocation of Glycogen Synthase Kinase-3β (GSK-3β), a Trigger of Permeability Transition, Is Kinase Activity-dependent and Mediated by Interaction with Voltage-dependent Anion Channel 2 (VDAC2)
- (2014) Masaya Tanno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition
- (2014) Michela Carraro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex
- (2014) C. Datler et al. JOURNAL OF CELL SCIENCE
- Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors
- (2014) Koteswara Rao Valasani et al. Journal of Chemical Information and Modeling
- Cinnamic Anilides as New Mitochondrial Permeability Transition Pore Inhibitors Endowed with Ischemia-Reperfusion Injury Protective Effect in Vivo
- (2014) Daniele Fancelli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition
- (2014) Manuel Gutiérrez-Aguilar et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Myelodysplastic syndromes
- (2014) Lionel Adès et al. LANCET
- Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans
- (2014) En-Zhi Shen et al. NATURE
- Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
- (2014) Dmitry B. Zorov et al. PHYSIOLOGICAL REVIEWS
- Attenuation of Skeletal Muscle and Renal Injury to the Lower Limb following Ischemia-Reperfusion Using mPTP Inhibitor NIM-811
- (2014) David Garbaisz et al. PLoS One
- An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
- (2014) K. N. Alavian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chaperoning mitochondrial permeability transition: regulation of transition pore complex by a J-protein, DnaJC15
- (2014) D Sinha et al. Cell Death & Disease
- Perturbed mitochondrial Ca2+signals as causes or consequences of mitophagy induction
- (2013) Alessandro Rimessi et al. Autophagy
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F₀-ATP synthase
- (2013) Marie Bergeaud et al. CELL CYCLE
- Role of the c subunit of the FOATP synthase in mitochondrial permeability transition
- (2013) Massimo Bonora et al. CELL CYCLE
- Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner
- (2013) A Bononi et al. CELL DEATH AND DIFFERENTIATION
- Redox-sensitive glycogen synthase kinase 3β-directed control of mitochondrial permeability transition: rheostatic regulation of acute kidney injury
- (2013) Zhen Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- How Parkinsonian Toxins Dysregulate the Autophagy Machinery
- (2013) Ruben Dagda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial Alterations near Amyloid Plaques in an Alzheimer's Disease Mouse Model
- (2013) Hong Xie et al. JOURNAL OF NEUROSCIENCE
- Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
- (2013) P. A. Parone et al. JOURNAL OF NEUROSCIENCE
- The role of the mitochondrial calcium uniporter in cerebral ischemia/reperfusion injury in rats involves regulation of mitochondrial energy metabolism
- (2013) QIN ZHAO et al. Molecular Medicine Reports
- The mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice
- (2013) Lee J. Martin et al. NEUROBIOLOGY OF AGING
- H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling
- (2013) A Rimessi et al. ONCOGENE
- Dimers of mitochondrial ATP synthase form the permeability transition pore
- (2013) V. Giorgio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
- (2013) A. Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
- (2013) Jason Karch et al. eLife
- ROS‐Mediated PARP Activity Undermines Mitochondrial Function After Permeability Transition Pore Opening During Myocardial Ischemia–Reperfusion
- (2013) Jacqueline M. Schriewer et al. Journal of the American Heart Association
- Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle
- (2013) E.P. Taddeo et al. Molecular Metabolism
- The Role of Lipids in VDAC Oligomerization
- (2012) Viktoria Betaneli et al. BIOPHYSICAL JOURNAL
- p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
- (2012) Angelina V. Vaseva et al. CELL
- Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production
- (2012) Rongxue Wu et al. EMBO Molecular Medicine
- Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- CypD−/− hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism
- (2012) Sara Menazza et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Inhibition of glycogen synthase kinase-3β prevents NSAID-induced acute kidney injury
- (2012) Hao Bao et al. KIDNEY INTERNATIONAL
- Regulation of mitochondrial permeability transition pore by PINK1
- (2012) Clement A Gautier et al. Molecular Neurodegeneration
- Programmed necrosis in acute kidney injury
- (2012) A. Linkermann et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Bax regulates primary necrosis through mitochondrial dynamics
- (2012) R. S. Whelan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
- (2012) E. C. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of mitochondrial permeability transition in reperfusion-induced cardiomyocyte death depends on the duration of ischemia
- (2011) Marisol Ruiz-Meana et al. BASIC RESEARCH IN CARDIOLOGY
- Protective action of l-carnitine on cardiac mitochondrial function and structure against fatty acid stress
- (2011) Eri Oyanagi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation
- (2011) Jennifer R. Hom et al. DEVELOPMENTAL CELL
- Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts
- (2011) David Cotán et al. FASEB JOURNAL
- α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator
- (2011) Yuangang Zhu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Inhibition of Amyloid- (A ) Peptide-Binding Alcohol Dehydrogenase-A Interaction Reduces A Accumulation and Improves Mitochondrial Function in a Mouse Model of Alzheimer's Disease
- (2011) J. Yao et al. JOURNAL OF NEUROSCIENCE
- Interaction between cytokines and ammonia in the mitochondrial permeability transition in cultured astrocytes
- (2011) Veronica M. Alvarez et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase
- (2011) Kambiz N. Alavian et al. NATURE CELL BIOLOGY
- Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53
- (2011) Franz Hagn et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
- (2010) Raquel S. Carreira et al. Autophagy
- Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes
- (2010) Peter Pediaditakis et al. BIOCHEMICAL JOURNAL
- Cyclosporine A attenuates hypoxic–ischemic brain injury in newborn rats
- (2010) Jong Hee Hwang et al. BRAIN RESEARCH
- Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells
- (2010) J. C. Ghosh et al. CANCER RESEARCH
- Preclinical Characterization of Mitochondria-Targeted Small Molecule Hsp90 Inhibitors, Gamitrinibs, in Advanced Prostate Cancer
- (2010) B. H. Kang et al. CLINICAL CANCER RESEARCH
- Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice
- (2010) John W. Elrod et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release
- (2010) C. Giorgi et al. SCIENCE
- Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases
- (2010) Tara L. Davis et al. PLOS BIOLOGY
- Anesthetic-induced Preconditioning Delays Opening of Mitochondrial Permeability Transition Pore via Protein Kinase C-ϵ–mediated Pathway
- (2009) Danijel Pravdic et al. ANESTHESIOLOGY
- Cyclophilin D in mitochondrial pathophysiology
- (2009) Valentina Giorgio et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects inCol6a1−/−myopathic mice
- (2009) T Tiepolo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Gating of the Mitochondrial Permeability Transition Pore by Long Chain Fatty Acyl Analogsin Vivo
- (2009) Dmitri Samovski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effect of Transient and Permanent Permeability Transition Pore Opening on NAD(P)H Localization in Intact Cells
- (2009) Jean François Dumas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reversible Cyclosporin A-sensitive Mitochondrial Depolarization Occurs within Minutes of Stroke Onset in Mouse Somatosensory Cortexin Vivo
- (2009) Ran R. Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovering Potent Small Molecule Inhibitors of Cyclophilin A Using de Novo Drug Design Approach
- (2009) Shuaishuai Ni et al. JOURNAL OF MEDICINAL CHEMISTRY
- Bad Targets the Permeability Transition Pore Independent of Bax or Bak to Switch between Ca2+-Dependent Cell Survival and Death
- (2009) Soumya Sinha Roy et al. MOLECULAR CELL
- α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity
- (2009) Guangwei Liu et al. NEUROSCIENCE LETTERS
- Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition
- (2009) A. Rasola et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A peptide containing residues 26–44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator
- (2008) A. Atlante et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy
- (2008) J Reutenauer et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Mitochondrial Phosphate Carrier Interacts with Cyclophilin D and May Play a Key Role in the Permeability Transition
- (2008) Anna W. C. Leung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain
- (2008) Latha Devi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
- (2008) Heng Du et al. NATURE MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now