TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit

Title
TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit
Authors
Keywords
TNF-mediated necrosis, macrophage, tuberculosis, mitochondrion, ROS, Calcium, BAX, ER, ryanodine receptors, calcium channel blockers
Journal
CELL
Volume 178, Issue 6, Pages 1344-1361.e11
Publisher
Elsevier BV
Online
2019-08-29
DOI
10.1016/j.cell.2019.08.004

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