The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability

MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration

(2016) Anil Noronha Antony et al.   Nature Communications

Persistent increases in Ca2+ influx through Cav1.2 shortens action potential and causes Ca2+ overload-induced afterdepolarizations and arrhythmias

(2015) Xiaoying Zhang et al.   BASIC RESEARCH IN CARDIOLOGY

Standing of giants shoulders the story of the mitochondrial Na+Ca2+ exchanger

(2015) Israel Sekler   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial calcium and the regulation of metabolism in the heart

(2015) George S.B. Williams et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter

(2015) Kira M. Holmström et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons

(2015) Marko Kostic et al.   Cell Reports

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

(2015) Timothy S. Luongo et al.   Cell Reports

The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart

(2015) Jennifer Q. Kwong et al.   Cell Reports

Unresolved questions from the analysis of mice lacking MCU expression

(2014) Elizabeth Murphy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Calcium Movement in Cardiac Mitochondria

(2014) Liron Boyman et al.   BIOPHYSICAL JOURNAL

The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter

(2013) Xin Pan et al.   NATURE CELL BIOLOGY

EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

(2013) Y. Sancak et al.   SCIENCE

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

(2012) Karthik Mallilankaraman et al.   CELL

The mitochondrial Na+/Ca2+ exchanger

(2012) Raz Palty et al.   CELL CALCIUM

Lost in Transgenesis

(2012) Jennifer Davis et al.   CIRCULATION RESEARCH

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism

(2012) Karthik Mallilankaraman et al.   NATURE CELL BIOLOGY

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Elevated Cytosolic Na + Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes

(2010) Michael Kohlhaas et al.   CIRCULATION

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake

(2010) Fabiana Perocchi et al.   NATURE

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

(2009) R. Palty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing Mitochondrial Ca 2+ Uptake in Myocytes From Failing Hearts Restores Energy Supply and Demand Matching

(2008) Ting Liu et al.   CIRCULATION RESEARCH

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology