The f subunit of human ATP synthase is essential for normal mitochondrial morphology and permeability transition

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

(2020) Till Stephan et al.   EMBO JOURNAL

Cryo-EM structure of the entire mammalian F-type ATP synthase

(2020) Gergely Pinke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the dimeric ATP synthase from bovine mitochondria

(2020) Tobias E. Spikes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore

(2019) Maria A. Neginskaya et al.   Cell Reports

Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows

(2019) Thorsten B. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

(2019) Eduardo Balsa et al.   MOLECULAR CELL

Arg-8 of yeast subunit e contributes to the stability of F-ATP synthase dimers and to the generation of the full-conductance mitochondrial megachannel

(2019) Lishu Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Persistence of the permeability transition pore in human mitochondria devoid of an assembled ATP synthase

(2019) Joe Carroll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1

(2019) Jinke Gu et al.   SCIENCE

Biochemical thresholds for pathological presentation of ATP synthase deficiencies

(2019) Hana Nuskova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore

(2019) Andrea Urbani et al.   Nature Communications

A mitochondrial megachannel resides in monomeric F1FO ATP synthase

(2019) Nelli Mnatsakanyan et al.   Nature Communications

Osmotic regulation of the mitochondrial permeability transition pore investigated by light scattering, fluorescence and electron microscopy techniques

(2018) Artyom Y. Baev et al.   ANALYTICAL BIOCHEMISTRY

Calcium and regulation of the mitochondrial permeability transition

(2018) Valentina Giorgio et al.   CELL CALCIUM

Assembly of the membrane domain of ATP synthase in human mitochondria

(2018) Jiuya He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane

(2018) Anurag P. Srivastava et al.   SCIENCE

Respiratory chain supercomplexes: Structures, function and biogenesis

(2018) Teresa Lobo-Jarne et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal

(2018) Lishu Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial genotype modulates mtDNA copy number and organismal phenotype in Drosophila

(2017) Tiina S. Salminen et al.   MITOCHONDRION

Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase

(2017) Jiuya He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase

(2017) Jiuya He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic model for the dimeric FOregion of mitochondrial ATP synthase

(2017) Hui Guo et al.   SCIENCE

Normalization of NAD+Redox Balance as a Therapy for Heart FailureClinical Perspective

(2016) Chi Fung Lee et al.   CIRCULATION

Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology

(2016) Alexander Hahn et al.   MOLECULAR CELL

The RING 2.0 web server for high quality residue interaction networks

(2016) Damiano Piovesan et al.   NUCLEIC ACIDS RESEARCH

The SWISS-MODEL Repository—new features and functionality

(2016) Stefan Bienert et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Rotary ATPases: A New Twist to an Ancient Machine

(2016) Werner Kühlbrandt et al.   TRENDS IN BIOCHEMICAL SCIENCES

Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

(2015) Sudeshna Roy et al.   ChemMedChem

Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking

(2015) Jennifer Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

F-ATPase ofDrosophila melanogasterForms 53-Picosiemen (53-pS) Channels Responsible for Mitochondrial Ca2+-induced Ca2+Release

(2014) Sophia von Stockum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition

(2014) Michela Carraro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

(2014) K. N. Alavian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

Human F1F0 ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter?

(2013) Johann Habersetzer et al.   PLoS One

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria

(2013) B. Daum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

(2012) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of idebenone on mitochondrial bioenergetics

(2011) Valentina Giorgio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Macromolecular organization of ATP synthase and complex I in whole mitochondria

(2011) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly and oligomerization of human ATP synthase lacking mitochondrial subunits a and A6L

(2010) Ilka Wittig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Row-like organization of ATP synthase in intact mitochondria determined by cryo-electron tomography

(2009) Natalya V. Dudkina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cyclophilin D in mitochondrial pathophysiology

(2009) Valentina Giorgio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Mitochondrial F1F0-ATP synthase and organellar internal architecture

(2009) Jean Velours et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cyclophilin D Modulates Mitochondrial F0F1-ATP Synthase by Interacting with the Lateral Stalk of the Complex

(2009) Valentina Giorgio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure of the membrane extrinsic region of bovine ATP synthase

(2009) D. M. Rees et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Intermembrane Space Loop of Subunitb(4) Is a Major Determinant of the Stability of Yeast Oligomeric ATP Synthases†

(2008) Théodore Weimann et al.   BIOCHEMISTRY

Cristae formation—linking ultrastructure and function of mitochondria

(2008) Michael Zick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL

Characterization of Domain Interfaces in Monomeric and Dimeric ATP Synthase

(2008) Ilka Wittig et al.   MOLECULAR & CELLULAR PROTEOMICS