NSAIDs and Cancer Resolution: New Paradigms beyond Cyclooxygenase

Resolution of inflammation: An organizing principle in biology and medicine

(2021) Dipak Panigrahy et al.   PHARMACOLOGY & THERAPEUTICS

Aspirin-Triggered Resolvin D1 Reduces Proliferation and the Neutrophil to Lymphocyte Ratio in a Mutant KRAS-Driven Lung Adenocarcinoma Model

(2021) Amanda Vannitamby et al.   Cancers

Targeting Ca2+ signaling: A new arsenal against cancer

(2021) Suman Panda et al.   DRUG DISCOVERY TODAY

Non‐Steroidal Anti‐Inflammatory Drugs (NSAIDs) sensitize melanoma cells to MEK inhibition and inhibit metastasis and relapse by inducing degradation of AXL

(2021) Yingshi Chen et al.   Pigment Cell & Melanoma Research

Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

(2020) Zhihang Chen et al.   MOLECULAR MEDICINE

Cytokine storm during chemotherapy: a new companion diagnostic emerges?

(2020) Panagiota S. Filippou et al.   Oncotarget

Plasma Membrane Ca2+ ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer

(2020) Pishyaporn Sritangos et al.   Cancers

Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

(2020) Dipak Panigrahy et al.   CANCER AND METASTASIS REVIEWS

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges

(2020) Zhilin Zou et al.   Cell and Bioscience

Eicosanoids

(2020) Bruce D. Hammock et al.   AMERICAN JOURNAL OF PATHOLOGY

PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity

(2020) Gary A. Piazza et al.   DRUG DISCOVERY TODAY

Carcinogenesis: Failure of resolution of inflammation?

(2020) Anna Fishbein et al.   PHARMACOLOGY & THERAPEUTICS

Aspirin suppresses tumor cell-induced angiogenesis and their incongruity

(2019) Gargi Maity et al.   Journal of Cell Communication and Signaling

Aspirin-triggered proresolving mediators stimulate resolution in cancer

(2019) Molly M. Gilligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression Profiling of Calcium Channels and Calcium-Activated Potassium Channels in Colorectal Cancer

(2019) Ibrahim et al.   Cancers

T‐type calcium channels drive the proliferation of androgen‐receptor negative prostate cancer cells

(2019) Roberto Silvestri et al.   PROSTATE

Targeting the Canonical WNT/β-Catenin Pathway in Cancer Treatment Using Non-Steroidal Anti-Inflammatory Drugs

(2019) Vallée et al.   Cells

WNT/β-Catenin Signaling Pathway Regulating T Cell-Inflammation in the Tumor Microenvironment

(2019) Xin Li et al.   Frontiers in Immunology

Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression

(2019) Pan Zhang et al.   PLoS One

Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant Prostate Cancer

(2019) Roberto Benelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ibuprofen reduces cell proliferation through inhibiting Wnt/β catenin signaling pathway in gastric cancer stem cells

(2018) Hassan Akrami et al.   CELL BIOLOGY INTERNATIONAL

Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site

(2018) Srishti Singh et al.   MOLECULES

Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia

(2018) Hélène Cabanas et al.   Oncotarget

Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway

(2018) Yongzeng Ding et al.   Nutrients

Prostaglandin E2 Secreted by Thyroid Cancer Cells Contributes to Immune Escape Through the Suppression of Natural Killer (NK) Cell Cytotoxicity and NK Cell Differentiation

(2018) Arum Park et al.   Frontiers in Immunology

The Akt pathway in oncology therapy and beyond (Review)

(2018) George Nitulescu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Association of Analgesic Use With Risk of Ovarian Cancer in the Nurses’ Health Studies

(2018) Mollie E. Barnard et al.   JAMA Oncology

Wnt/beta-catenin pathway: modulating anticancer immune response

(2017) Sachin Gopalkrishna Pai et al.   Journal of Hematology & Oncology

Cardiovascular safety of non-steroidal anti-inflammatory drugs revisited

(2017) Chris Walker et al.   POSTGRADUATE MEDICINE

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth

(2017) Chiara Di Malta et al.   SCIENCE

Voltage-gated calcium channels: Novel targets for cancer therapy

(2017) Nam Nhut Phan et al.   Oncology Letters

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer

(2017) Dominika E. Butler et al.   Oncotarget

Celecoxib targets breast cancer stem cells by inhibiting the synthesis of prostaglandin E2 and down-regulating the Wnt pathway activity

(2017) Chaolin Huang et al.   Oncotarget

Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling

(2017) Bing Zhu et al.   Oncotarget

Inflammatory responses and inflammation-associated diseases in organs

(2017) Linlin Chen et al.   Oncotarget

Autophagy: novel applications of nonsteroidal anti-inflammatory drugs for primary cancer

(2017) Chen Yu et al.   Cancer Medicine

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells

(2017) Bruno R. B. Pires et al.   PLoS One

Celecoxib exerts antitumor effects in HL-60 acute leukemia cells and inhibits autophagy by affecting lysosome function

(2016) Ying Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

Canonical Wnt/β-Catenin Signaling Pathway Is Dysregulated in Patients With Primary and Secondary Myelofibrosis

(2016) Marko Lucijanic et al.   Clinical Lymphoma Myeloma & Leukemia

Aspirin-triggered resolvin D1 inhibits TGF-β1-induced EMT through the inhibition of the mTOR pathway by reducing the expression of PKM2 and is closely linked to oxidative stress

(2016) Yu Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Inhibition of NF-kappa B pathway leads to deregulation of epithelial–mesenchymal transition and neural invasion in pancreatic cancer

(2016) Alice Nomura et al.   LABORATORY INVESTIGATION

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer

(2016) Yaqing Chen et al.   Oncotarget

PPAR-delta promotes survival of breast cancer cells in harsh metabolic conditions

(2016) X Wang et al.   Oncogenesis

Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation

(2016) Bin Ma et al.   Frontiers in Immunology

Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer

(2016) Amol Suryawanshi et al.   Frontiers in Immunology

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

(2016) Mi Park et al.   Cells

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Effect of COX-2 inhibitors and other non-steroidal inflammatory drugs on breast cancer risk: a meta-analysis

(2015) María de Pedro et al.   BREAST CANCER RESEARCH AND TREATMENT

 -Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells

(2015) Y. Hong et al.   CANCER RESEARCH

Blocking autophagy enhances meloxicam lethality to hepatocellular carcinoma by promotion of endoplasmic reticulum stress

(2015) Jingtao Zhong et al.   CELL PROLIFERATION

The Role of β-Catenin in Bcr/Abl Negative Myeloproliferative Neoplasms: An Immunohistochemical Study

(2015) Ayfer Geduk et al.   Clinical Lymphoma Myeloma & Leukemia

Aspirin and NSAIDs for breast cancer chemoprevention

(2015) Eugenia Ch Yiannakopoulou   EUROPEAN JOURNAL OF CANCER PREVENTION

Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: A case-control analysis

(2015) Claudia Becker et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting Wnt pathway in mantle cell lymphoma-initiating cells

(2015) Rohit Mathur et al.   Journal of Hematology & Oncology

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP

(2015) S J H Ricoult et al.   ONCOGENE

Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use

(2015) Jaromir Pastorek et al.   SEMINARS IN CANCER BIOLOGY

Expression of COX-2 and HER-2 in colorectal cancer and their correlation

(2015) Qi-Bing Wu   WORLD JOURNAL OF GASTROENTEROLOGY

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer

(2015) Youn-Sang Jung et al.   Oncotarget

Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype

(2015) Gyu-Beom Jang et al.   Scientific Reports

Low-dose aspirin use and the risk of ovarian cancer in Denmark

(2014) L. Baandrup et al.   ANNALS OF ONCOLOGY

Upregulation of MAPK/Erk and PI3K/Akt pathways in ulcerative colitis-associated colon cancer

(2014) Shruti Setia et al.   BIOMEDICINE & PHARMACOTHERAPY

Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor

(2014) H Nishio et al.   BRITISH JOURNAL OF CANCER

Clinical and Molecular Genetics of the Phosphodiesterases (PDEs)

(2014) Monalisa F. Azevedo et al.   ENDOCRINE REVIEWS

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Current clinical regulation of PI3K/PTEN/Akt/mTOR signalling in treatment of human cancer

(2014) Hui Jun Lim et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Role of p38 MAPK in enhanced human cancer cells killing by the combination of aspirin and ABT-737

(2014) Chong Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TLR2-Dependent Activation of β-Catenin Pathway in Dendritic Cells Induces Regulatory Responses and Attenuates Autoimmune Inflammation

(2014) Indumathi Manoharan et al.   JOURNAL OF IMMUNOLOGY

Aspirin, Nonaspirin Nonsteroidal Anti-inflammatory Drug, and Acetaminophen Use and Risk of Invasive Epithelial Ovarian Cancer: A Pooled Analysis in the Ovarian Cancer Association Consortium

(2014) B. Trabert et al.   JNCI-Journal of the National Cancer Institute

Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses

(2014) Yanyan Yang et al.   MEDIATORS OF INFLAMMATION

The Wnt/β-Catenin Signaling Pathway Controls the Inflammatory Response in Infections Caused by Pathogenic Bacteria

(2014) Octavio Silva-García et al.   MEDIATORS OF INFLAMMATION

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity

(2014) N Li et al.   ONCOGENE

Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species

(2014) Deepa R. Avisetti et al.   PLoS One

Meloxicam Executes Its Antitumor Effects against Hepatocellular Carcinoma in COX-2- Dependent and -Independent Pathways

(2014) Xiaofeng Dong et al.   PLoS One

Inhibition Mechanism of the Intracellular Transporter Ca2+-Pump from Sarco-Endoplasmic Reticulum by the Antitumor Agent Dimethyl-Celecoxib

(2014) Ramón Coca et al.   PLoS One

Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

(2014) Bin Deng et al.   PLoS One

COX-2 Inhibition Potentiates Antiangiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models

(2014) L. Xu et al.   Science Translational Medicine

Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell

(2014) Hassan Akrami et al.   TUMOR BIOLOGY

Preventive Effects of NSAIDs, NO-NSAIDs, and NSAIDs Plus Difluoromethylornithine in a Chemically Induced Urinary Bladder Cancer Model

(2013) H. L. Nicastro et al.   Cancer Prevention Research

Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K

(2013) M.-S. Kim et al.   Cancer Prevention Research

The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype

(2013) Jesmond Dalli et al.   FASEB JOURNAL

MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis

(2013) Junchao Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/ -Catenin Signaling

(2013) N. Li et al.   MOLECULAR CANCER THERAPEUTICS

Indomethacin Inhibits Cancer Cell Migration via Attenuation of Cellular Calcium Mobilization

(2013) Yuh-Cherng Guo et al.   MOLECULES

Nonsteroidal Anti-inflammatory Drugs Diclofenac and Celecoxib Attenuates Wnt/β-Catenin/Tcf Signaling Pathway in Human Glioblastoma Cells

(2013) Gangadhara Reddy Sareddy et al.   NEUROCHEMICAL RESEARCH

High-Dose Aspirin Consumption Contributes to Decreased Risk for Pancreatic Cancer in a Systematic Review and Meta-analysis

(2013) Xi-Jun Cui et al.   PANCREAS

Natural resolution of inflammation

(2013) Marcelo O. Freire et al.   PERIODONTOLOGY 2000

Celecoxib-Induced Cytotoxic Effect Is Potentiated by Inhibition of Autophagy in Human Urothelial Carcinoma Cells

(2013) Kuo-How Huang et al.   PLoS One

Lipid mediators in immune dysfunction after severe inflammation

(2013) James N. Fullerton et al.   TRENDS IN IMMUNOLOGY

High dose NSAIDs may double the risk of heart attacks and heart failure, says new study

(2013) K. Chinthapalli   BMJ-British Medical Journal

The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer

(2012) Xingya Wang et al.   BIOCHEMICAL PHARMACOLOGY

Stimulation of cytosolic and mitochondrial calcium mobilization by indomethacin in Caco-2 cells: Modulation by the polyphenols quercetin, resveratrol and rutin

(2012) Catalina Carrasco-Pozo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Aspirin but not ibuprofen use is associated with reduced risk of prostate cancer: a PLCO Study

(2012) F M Shebl et al.   BRITISH JOURNAL OF CANCER

Autophagy limits the cytotoxic effects of the AKT inhibitor AZ7328 in human bladder cancer cells

(2012) Rian J. Dickstein et al.   CANCER BIOLOGY & THERAPY

Genetic and Pharmacologic Inhibition of β-Catenin Targets Imatinib-Resistant Leukemia Stem Cells in CML

(2012) Florian H. Heidel et al.   Cell Stem Cell

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

(2012) Charles N. Serhan et al.   FASEB JOURNAL

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

(2012) Farhat V.N. Din et al.   GASTROENTEROLOGY

Nonsteroidal Anti-inflammatory Drug Use, Chronic Liver Disease, and Hepatocellular Carcinoma

(2012) Vikrant V. Sahasrabuddhe et al.   JNCI-Journal of the National Cancer Institute

Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials

(2012) Peter M Rothwell et al.   LANCET

Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials

(2012) Annemijn M Algra et al.   LANCET ONCOLOGY

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Beta-catenin inhibits melanocyte migration but induces melanoma metastasis

(2012) S J Gallagher et al.   ONCOGENE

Functional expression of voltage-gated calcium channels in human melanoma

(2012) A. Das et al.   Pigment Cell & Melanoma Research

Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolvin and protectin formation

(2012) Karsten H. Weylandt et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Pro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in Inflammation

(2012) Antonio Recchiuti et al.   Frontiers in Immunology

Nonsteroidal Antiinflammatory Drugs and Bladder Cancer: A Pooled Analysis

(2011) S. E. Daugherty et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Role of lipoxins, resolvins, and other bioactive lipids in colon and pancreatic cancer

(2011) Naveena B. Janakiram et al.   CANCER AND METASTASIS REVIEWS

β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas

(2011) William E. Damsky et al.   CANCER CELL

Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/ -Catenin-Mediated Transcription in Human Breast Tumor Cells

(2011) H. N. Tinsley et al.   Cancer Prevention Research

Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF- 

(2011) K. H. Weylandt et al.   CARCINOGENESIS

Resolvins and Protectins in Inflammation Resolution

(2011) Charles N. Serhan et al.   CHEMICAL REVIEWS

Novel Proresolving Aspirin-Triggered DHA Pathway

(2011) Charles N. Serhan et al.   CHEMISTRY & BIOLOGY

Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes

(2011) N. K. Tafreshi et al.   CLINICAL CANCER RESEARCH

COXIBs, CINODs and H2S-Releasing NSAIDs: Current Perspectives in the Development of Safer Non Steroidal Anti-Inflammatory Drugs

(2011) S. Fiorucci et al.   CURRENT MEDICINAL CHEMISTRY

Meta-analysis: non-steroidal anti-inflammatory drug use and the risk of esophageal squamous cell carcinoma

(2011) Lei Sun et al.   DISEASES OF THE ESOPHAGUS

DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines

(2011) Mitsutoshi Kadowaki et al.   INTERNATIONAL JOURNAL OF CANCER

The wnt/β-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer

(2011) Taj D. King et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

(2011) Sungwhan F. Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Lipoxin and Aspirin-Triggered Lipoxins

(2011) Mario Romano   TheScientificWorldJOURNAL

Celecoxib inhibits cell proliferation through the activation of ERK and p38 MAPK in head and neck squamous cell carcinoma cell lines

(2010) Seok-Woo Park et al.   ANTI-CANCER DRUGS

Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells

(2010) Shengbing Huang et al.   Autophagy

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Selective cyclooxygenase-2 (COX-2) inhibitors and breast cancer risk

(2010) Varun Ashok et al.   BREAST

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion

(2010) Y Wu et al.   BRITISH JOURNAL OF CANCER

Nuclear factor κB transcription factors are coexpressed and convey a poor outcome in ovarian cancer

(2010) Christina M. Annunziata et al.   CANCER

Colon Tumor Cell Growth-Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 Inhibition

(2010) H. N. Tinsley et al.   Cancer Prevention Research

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells

(2010) Mahmoud Youns et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chemoprevention of Nonmelanoma Skin Cancer With Celecoxib: A Randomized, Double-Blind, Placebo-Controlled Trial

(2010) Craig A. Elmets et al.   JNCI-Journal of the National Cancer Institute

NSAID Inhibition of Prostate Cancer Cell Migration Is Mediated by Nag-1 Induction via the p38 MAPK-p75NTR Pathway

(2010) S. Wynne et al.   MOLECULAR CANCER RESEARCH

Analysis of NSAID-Activated Gene 1 Expression in Prostate Cancer

(2010) Takashi Kawahara et al.   UROLOGIA INTERNATIONALIS

MAPK signaling in inflammation-associated cancer development

(2010) Pengyu Huang et al.   Protein & Cell

A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2

(2009) Genzo Iguchi et al.   CANCER LETTERS

Prevention of Nonsteroidal Anti-Inflammatory Drug-Induced Ulcer: Looking to the Future

(2009) Stefano Fiorucci   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Economic evaluation of nonsteroidal anti-inflammatory drug strategies in rheumatoid arthritis

(2009) András Inotai et al.   INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

(2009) H. N. Tinsley et al.   MOLECULAR CANCER THERAPEUTICS

Effect of non-steroidal anti-inflammatory drugs on non-melanoma skin cancer incidence in the SKICAP-AK trial

(2009) Mary C. Clouser et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Cyclooxygenase-inhibiting nitric oxide donators for osteoarthritis

(2009) John L. Wallace et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Carbonic anhydrase IX in oligodendroglial brain tumors

(2008) Sally Järvelä et al.   BMC CANCER

Multi-targeted therapy of cancer by omega-3 fatty acids

(2008) Isabelle M. Berquin et al.   CANCER LETTERS

Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor γ synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells

(2008) Wei-Hao Sun et al.   CANCER LETTERS

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

(2008) J. Chiche et al.   CANCER RESEARCH

WNT5A Exhibits Tumor-Suppressive Activity through Antagonizing the Wnt/ -Catenin Signaling, and Is Frequently Methylated in Colorectal Cancer

(2008) J. Ying et al.   CLINICAL CANCER RESEARCH

Role of peroxisome-proliferator-activated receptor β/δ (PPARβ/δ) in gastrointestinal tract function and disease

(2008) Jeffrey M. Peters et al.   CLINICAL SCIENCE

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Sulindac suppresses β-catenin expression in human cancer cells

(2008) Anjia Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TNF: A master switch for inflammation to cancer

(2008) Gautam Sethi   Frontiers in Bioscience-Landmark

OncogenicK-ras promotes early carcinogenesis in the mouse proximal colon

(2008) Shelly R. Calcagno et al.   INTERNATIONAL JOURNAL OF CANCER

The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells

(2008) Zhen Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

(2008) Kevin M Haigis et al.   NATURE GENETICS

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling

(2008) Steven Hoseong Yang et al.   NATURE GENETICS

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE

Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?

(2008) John L. Wallace   PHYSIOLOGICAL REVIEWS

The Role of PPARs in Cancer

(2008) Keisuke Tachibana et al.   PPAR Research