Blocking autophagy enhances meloxicam lethality to hepatocellular carcinoma by promotion of endoplasmic reticulum stress

Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway

(2015) Bin Tang et al.   Autophagy

The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer

(2015) Shu-Wen Hsuan et al.   EUROPEAN JOURNAL OF NUTRITION

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma

(2015) Mohamed A.Y. Abdel Malek et al.   Oncotarget

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells

(2015) Xiang-Yang Zhang et al.   Molecular Brain

Ulinastatin Reduces the Resistance of Liver Cancer Cells to Epirubicin by Inhibiting Autophagy

(2015) Bin Song et al.   PLoS One

Heat-Modified Citrus Pectin Induces Apoptosis-Like Cell Death and Autophagy in HepG2 and A549 Cancer Cells

(2015) Lionel Leclere et al.   PLoS One

COX-2 overexpression increases malignant potential of human glioma cells through Id1

(2015) Kaiming Xu et al.   Oncotarget

Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN

(2015) Tian-Huei Chu et al.   Oncotarget

A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents

(2015) Roberta Bortolozzi et al.   Oncotarget

The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy

(2014) Chul-Su Yang et al.   Autophagy

Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function

(2014) Edward P. Chen et al.   CARCINOGENESIS

COX-2-Independent Effects of Celecoxib Sensitize Lymphoma B Cells to TRAIL-Mediated Apoptosis

(2014) A.-S. Gallouet et al.   CLINICAL CANCER RESEARCH

Hepatocellular carcinoma: clinical frontiers and perspectives

(2014) Jordi Bruix et al.   GUT

Treatment for hepatocellular carcinoma in Japan over the last three decades: Our experience and published work review

(2014) Yukio Osaki et al.   HEPATOLOGY RESEARCH

Meloxicam Executes Its Antitumor Effects against Hepatocellular Carcinoma in COX-2- Dependent and -Independent Pathways

(2014) Xiaofeng Dong et al.   PLoS One

Glucose-Regulated Protein 78 (Grp78) Confers Chemoresistance to Tumor Endothelial Cells under Acidic Stress

(2014) Fernanda Visioli et al.   PLoS One

ER stress and ER stress-induced apoptosis are activated in gastric SMCs in diabetic rats

(2014) Xia Chen   WORLD JOURNAL OF GASTROENTEROLOGY

Blockade of Autophagy Aggravates Endoplasmic Reticulum Stress and Improves Paclitaxel Cytotoxicity in Human Cervical Cancer Cells

(2014) Li Xu et al.   Cancer Research and Treatment

Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma

(2013) Xiao-Wen Liu et al.   Autophagy

Celecoxib enhances radiosensitivity of hypoxic glioblastoma cells through endoplasmic reticulum stress

(2013) Kenshi Suzuki et al.   NEURO-ONCOLOGY

Protective Role of AMP-Activated Protein Kinase-Evoked Autophagy on an In Vitro Model of Ischemia/Reperfusion-Induced Renal Tubular Cell Injury

(2013) Li-Ting Wang et al.   PLoS One

Celecoxib-Induced Cytotoxic Effect Is Potentiated by Inhibition of Autophagy in Human Urothelial Carcinoma Cells

(2013) Kuo-How Huang et al.   PLoS One

Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness

(2012) K. L. Cook et al.   CANCER RESEARCH

AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers

(2012) Michael J. Gray et al.   INTERNATIONAL JOURNAL OF CANCER

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Down-Regulation of Glucose-Regulated Protein (GRP) 78 Potentiates Cytotoxic Effect of Celecoxib in Human Urothelial Carcinoma Cells

(2012) Kuo-How Huang et al.   PLoS One

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

(2011) Ying-Hong Shi et al.   Autophagy

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Aggravated Endoplasmic Reticulum Stress as a Basis for Enhanced Glioblastoma Cell Killing by Bortezomib in Combination with Celecoxib or Its Non-Coxib Analogue, 2,5-Dimethyl-Celecoxib

(2008) A. Kardosh et al.   CANCER RESEARCH

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

(2008) Ann-Lii Cheng et al.   LANCET ONCOLOGY

Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells

(2008) J. J. Virrey et al.   MOLECULAR CANCER RESEARCH

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE