Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

The rise and fall of aspirin in the primary prevention of cardiovascular disease

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PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer

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Long non-coding RNA HOTTIP affects renal cell carcinoma progression by regulating autophagy via the PI3K/Akt/Atg13 signaling pathway

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Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer

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Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement

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The PI3K/AKT Pathway as a Target for Cancer Treatment

(2016) Ingrid A. Mayer et al.   Annual Review of Medicine

Aspirin and Cancer

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(2016) Stephen J. D. O'Keefe   Nature Reviews Gastroenterology & Hepatology

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(2016) Vanessa Balchen et al.   Clinical Interventions in Aging

mTOR pathway in colorectal cancer: an update

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Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer

(2013) Enric Domingo et al.   JOURNAL OF CLINICAL ONCOLOGY

Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1

(2013) I. Ben-Sahra et al.   SCIENCE

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Comprehensive molecular characterization of human colon and rectal cancer

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Aspirin Use, TumorPIK3CAMutation, and Colorectal-Cancer Survival

(2012) Xiaoyun Liao et al.   NEW ENGLAND JOURNAL OF MEDICINE

LC3 and GATE-16 N Termini Mediate Membrane Fusion Processes Required for Autophagosome Biogenesis

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Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms

(2011) Pixu Liu et al.   NATURE MEDICINE

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Effect of aspirin and NSAIDs on risk and survival from colorectal cancer

(2010) Farhat V N Din et al.   GUT

Autophagy, Immunity, and Microbial Adaptations

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Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE