NAD + Metabolism in Cardiac Health, Aging, and Disease

NAD+ and Cardiovascular Diseases

(2021) Qiuzhen Lin et al.   CLINICA CHIMICA ACTA

NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway

(2021) Lei Zhou et al.   Oxidative Medicine and Cellular Longevity

Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells

(2021) Andrey Kropotov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment

(2021) David J.A. Jenkins et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondrial protective effects of PARP-inhibition in hypertension-induced myocardial remodeling and in stressed cardiomyocytes

(2021) K. Ordog et al.   LIFE SCIENCES

Nicotinamide for the treatment of heart failure with preserved ejection fraction

(2021) Mahmoud Abdellatif et al.   Science Translational Medicine

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside

(2021) Sarmistha Mukherjee et al.   JCI Insight

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

(2021) David E. Harrison et al.   AGING CELL

Evolving concepts in NAD+ metabolism

(2021) Claudia C.S. Chini et al.   Cell Metabolism

Cardiac Energy Metabolism in Heart Failure

(2021) Gary D. Lopaschuk et al.   CIRCULATION RESEARCH

NAD + Repletion Reverses Heart Failure with Preserved Ejection Fraction

(2021) Dan Tong et al.   CIRCULATION RESEARCH

Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy

(2021) Shin-ichi Oka et al.   CIRCULATION RESEARCH

Leveraging clinical epigenetics in heart failure with preserved ejection fraction: a call for individualized therapies

(2021) Nazha Hamdani et al.   EUROPEAN HEART JOURNAL

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women

(2021) Mihoko Yoshino et al.   SCIENCE

NAD+ metabolism and cardiometabolic health: the human evidence

(2021) Mahmoud Abdellatif et al.   CARDIOVASCULAR RESEARCH

NAD + Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy

(2021) Ying Ann Chiao et al.   Circulation-Heart Failure

Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation

(2021) Keke Wu et al.   LIFE SCIENCES

NAD+ flux is maintained in aged mice despite lower tissue concentrations

(2021) Melanie R. McReynolds et al.   Cell Systems

Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway

(2020) Igor Shats et al.   Cell Metabolism

The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolism

(2020) Magdolna Szántó et al.   GENES & DEVELOPMENT

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

(2020) Carlijn M E Remie et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

CD38: A Potential Therapeutic Target in Cardiovascular Disease

(2020) Wanyun Zuo et al.   CARDIOVASCULAR DRUGS AND THERAPY

Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

(2020) Eija Pirinen et al.   Cell Metabolism

Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor

(2020) Yejun Zou et al.   DEVELOPMENTAL CELL

Modulation of the cardiac sodium channel NaV1.5 peak and late currents by NAD+ precursors

(2020) Daniel S. Matasic et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism

(2020) Weiqi Hong et al.   Frontiers in Cell and Developmental Biology

CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions

(2020) Xingyue Zhang et al.   Frontiers in Cell and Developmental Biology

NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux

(2020) You-Jun Zhang et al.   BASIC RESEARCH IN CARDIOLOGY

Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure

(2020) Michael Thomas Davidson et al.   CIRCULATION RESEARCH

Age-related NAD+ decline

(2020) Melanie R. McReynolds et al.   EXPERIMENTAL GERONTOLOGY

Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

(2020) Aitziber Buqué et al.   Nature Communications

Nicotinamide adenine dinucleotide: Biosynthesis, consumption and therapeutic role in cardiac diseases

(2020) Cynthia Tannous et al.   Acta Physiologica

Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure

(2020) Bo Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

SLC25A51 is a mammalian mitochondrial NAD+ transporter

(2020) Timothy S. Luongo et al.   NATURE

MCART1/SLC25A51 is required for mitochondrial NAD transport

(2020) Nora Kory et al.   Science Advances

Hallmarks of Health

(2020) Carlos López-Otín et al.   CELL

Nicotinamide riboside reduces cardiometabolic risk factors and modulates cardiac oxidative stress in obese Wistar rats under caloric restriction

(2020) Josimar Macedo de Castro et al.   LIFE SCIENCES

NAD+ metabolism and its roles in cellular processes during ageing

(2020) Anthony J. Covarrubias et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import

(2020) Enrico Girardi et al.   Nature Communications

Inhibition of CD38 with the thiazoloquin(az)olin(on)e 78c protects the heart against post-ischemic injury

(2019) James Boslett et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Exploring and comparing adverse events between PARP inhibitors

(2019) Christopher J LaFargue et al.   LANCET ONCOLOGY

DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation

(2019) Deli Zhang et al.   Nature Communications

Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence

(2019) Rhys Anderson et al.   EMBO JOURNAL

Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca 2+ -ATPase in Heart Failure

(2019) Przemyslaw A Gorski et al.   CIRCULATION RESEARCH

Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice

(2019) Yuan-yuan Kong et al.   ACTA PHARMACOLOGICA SINICA

Nitrosative stress drives heart failure with preserved ejection fraction

(2019) Gabriele G. Schiattarella et al.   NATURE

Both gain and loss of Nampt function promote pressure-overload-induced heart failure

(2019) Jaemin Byun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice

(2019) Mitsukuni Yoshida et al.   Cell Metabolism

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

(2019) Stefano Tarantini et al.   Redox Biology

Autophagy promotes longevity—except in the presence of ‘leaky’ mitochondria

(2019) Mahmoud Abdellatif   CARDIOVASCULAR RESEARCH

Exogenous nicotinamide adenine dinucleotide administration alleviates ischemia/reperfusion-induced oxidative injury in isolated rat hearts via Sirt5-SDH-succinate pathway

(2019) Ling Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

(2019) Yasir S. Elhassan et al.   Cell Reports

Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice

(2019) Xue Han et al.   PeerJ

Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide

(2019) Tetsuo Horimatsu et al.   CARDIOVASCULAR RESEARCH

NAD+ in Brain Aging and Neurodegenerative Disorders

(2019) Sofie Lautrup et al.   Cell Metabolism

Melatonin and Nicotinamide Mononucleotide Attenuate Myocardial Ischemia/Reperfusion Injury via Modulation of Mitochondrial Function and Hemodynamic Parameters in Aged Rats

(2019) Leila Hosseini et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men

(2019) Ole L. Dollerup et al.   JOURNAL OF PHYSIOLOGY-LONDON

NAD+ homeostasis in renal health and disease

(2019) Kenneth M. Ralto et al.   Nature Reviews Nephrology

Cardiomyocyte Sirt (Sirtuin) 7 Ameliorates Stress-Induced Cardiac Hypertrophy by Interacting With and Deacetylating GATA4

(2019) Satoru Yamamura et al.   HYPERTENSION

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

(2018) Ole L Dollerup et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

PARP-1 inhibition attenuates cardiac fibrosis induced by myocardial infarction through regulating autophagy

(2018) Haibing Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders

(2018) Robert J. Henning et al.   Cardiovascular Toxicology

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

(2018) Sarah J. Mitchell et al.   Cell Metabolism

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD + Decline

(2018) Mariana G. Tarragó et al.   Cell Metabolism

Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

(2018) Ling Liu et al.   Cell Metabolism

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides

(2018) James Boslett et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Supplemental Vitamins and Minerals for CVD Prevention and Treatment

(2018) David J.A. Jenkins et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

(2018) Christopher R. Martens et al.   Nature Communications

CD38 Deficiency Protects Heart from High Fat Diet-Induced Oxidative Stress Via Activating Sirt3/FOXO3 Pathway

(2018) Ling-Fang Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sirtuins and NAD + in the Development and Treatment of Metabolic and Cardiovascular Diseases

(2018) Alice E. Kane et al.   CIRCULATION RESEARCH

Rescue of biosynthesis of nicotinamide adenine dinucleotide protects the heart in cardiomyopathy caused by lamin A/C gene mutation

(2018) Nicolas Vignier et al.   HUMAN MOLECULAR GENETICS

De novo NAD+ biosynthetic impairment in acute kidney injury in humans

(2018) Ali Poyan Mehr et al.   NATURE MEDICINE

PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis

(2018) Maayan Waldman et al.   EXPERIMENTAL CELL RESEARCH

CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma

(2018) Fabio Morandi et al.   Frontiers in Immunology

Role of protein kinase C in metabolic regulation of the cardiac Na+ channel

(2017) Man Liu et al.   HEART RHYTHM

Synthesis of the Ca 2+ -mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling

(2017) Wee K. Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD38 promotes angiotensin II-induced cardiac hypertrophy

(2017) Xiao-Hui Guan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

NAD and the aging process: Role in life, death and everything in between

(2017) Claudia C.S. Chini et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel

(2017) Ajit Vikram et al.   NATURE MEDICINE

Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases

(2017) Kathleen A. Hershberger et al.   Nature Reviews Nephrology

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

(2017) Rachel S. Fletcher et al.   Molecular Metabolism

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

(2017) Nicolas Diguet et al.   CIRCULATION

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers

(2017) Sophia E. Airhart et al.   PLoS One

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

(2016) Natalie E. de Picciotto et al.   AGING CELL

Spectral transfer function analysis of respiratory hemodynamic fluctuations predicts end-diastolic stiffness in preserved ejection fraction heart failure

(2016) Mahmoud Abdellatif et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Metabolic Control of Longevity

(2016) Carlos López-Otín et al.   CELL

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

(2016) David W. Frederick et al.   Cell Metabolism

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

(2016) Kathryn F. Mills et al.   Cell Metabolism

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

(2016) Juliana Camacho-Pereira et al.   Cell Metabolism

Normalization of NAD+Redox Balance as a Therapy for Heart FailureClinical Perspective

(2016) Chi Fung Lee et al.   CIRCULATION

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway

(2016) Xiao-Hui Guan et al.   Oxidative Medicine and Cellular Longevity

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

(2016) Joanna Ratajczak et al.   Nature Communications

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

(2016) Samuel A. J. Trammell et al.   Nature Communications

NAMPT-Mediated NAD + Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice

(2016) Kelly L. Stromsdorfer et al.   Cell Reports

Echocardiography and invasive hemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study

(2015) Sara Leite et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of sirtuins in cardiac disease

(2015) Shouji Matsushima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

(2015) Stephan Winnik et al.   EUROPEAN HEART JOURNAL

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

(2015) Javier Traba et al.   JOURNAL OF CLINICAL INVESTIGATION

Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization

(2015) Shangyu Hong et al.   NATURE MEDICINE

A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention

(2015) Andrew C. Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

(2015) Shian-Huey Chiang et al.   PLoS One

Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction

(2014) Evandro Fei Fang et al.   CELL

A High-Fat Diet and NAD + Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome

(2014) Morten Scheibye-Knudsen et al.   Cell Metabolism

Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study

(2014) Vincenzo Libri et al.   LANCET

Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

(2014) Takanobu Yamamoto et al.   PLoS One

The Development of Diet-Induced Obesity and Glucose Intolerance in C57Bl/6 Mice on a High-Fat Diet Consists of Distinct Phases

(2014) Lynda M. Williams et al.   PLoS One

Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues

(2014) Valerio Mori et al.   PLoS One

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

(2013) Ana P. Gomes et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Myocardial Titin Hypophosphorylation Importantly Contributes to Heart Failure With Preserved Ejection Fraction in a Rat Metabolic Risk Model

(2013) Nazha Hamdani et al.   Circulation-Heart Failure

Continuous Inhibition of Poly(ADP-ribose) Polymerase Does Not Reduce Reperfusion Injury in Isolated Rat Heart

(2013) Kenya Nishizawa et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes

(2013) Soo Jin Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

(2013) Rafaela da Silva et al.   THROMBOSIS AND HAEMOSTASIS

Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling

(2012) Vinodkumar B. Pillai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

(2012) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Niacin improves lipid profile but not endothelial function in patients with coronary artery disease on high dose statin therapy

(2012) Andrew C. Philpott et al.   ATHEROSCLEROSIS

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy

(2012) Man Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Niacin: another look at an underutilized lipid-lowering medication

(2012) Julia C. Creider et al.   Nature Reviews Endocrinology

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective inhibitors of cardiac ADPR cyclase as novel anti-arrhythmic compounds

(2012) Aimo Kannt et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Nicotinamide Pretreatment Protects Cardiomyocytes against Hypoxia-Induced Cell Death by Improving Mitochondrial Stress

(2012) Da-Li Tong et al.   PHARMACOLOGY

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

(2011) Péter Bai et al.   Cell Metabolism

Niacin Inhibits Vascular Inflammation via the Induction of Heme Oxygenase-1

(2011) Ben J. Wu et al.   CIRCULATION

Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells

(2011) Andrey Nikiforov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Specific metabolic rates of major organs and tissues across adulthood: evaluation by mechanistic model of resting energy expenditure

(2010) ZiMian Wang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nicotinamide-rich diet protects the heart against ischaemia–reperfusion in mice: A crucial role for cardiac SUR2A

(2010) Andriy Sukhodub et al.   PHARMACOLOGICAL RESEARCH

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A

(2009) Carmen R. Valdivia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effect of nadcin on energy supply system and apoptosis in ischemia-reperfusion injury to the myocardium

(2009) G. V. Sukoyan et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes

(2009) Chiao-Po Hsu et al.   CIRCULATION RESEARCH

Cardiac Na + Current Regulation by Pyridine Nucleotides

(2009) Man Liu et al.   CIRCULATION RESEARCH

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL