NAD+ flux is maintained in aged mice despite lower tissue concentrations
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Title
NAD+ flux is maintained in aged mice despite lower tissue concentrations
Authors
Keywords
nicotinamide, NAD, NADH, aging, flux, sirtuins, CD38, PARP, riboside, mononucleotide, niacin, redox, SIRT1, PARP1
Journal
Cell Systems
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-09-23
DOI
10.1016/j.cels.2021.09.001
References
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Note: Only part of the references are listed.- The Biochemical Pathways of Nicotinamide-Derived Pyridones
- (2021) Faisal Hayat et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Age-related NAD+ decline
- (2020) Melanie R. McReynolds et al. EXPERIMENTAL GERONTOLOGY
- Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction
- (2020) Xiaojing Wei et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- SLC25A51 is a mammalian mitochondrial NAD+ transporter
- (2020) Timothy S. Luongo et al. NATURE
- MCART1/SLC25A51 is required for mitochondrial NAD transport
- (2020) Nora Kory et al. Science Advances
- Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import
- (2020) Enrico Girardi et al. Nature Communications
- NMNAT2‐mediated NAD + generation is essential for quality control of aged oocytes
- (2019) Xinghan Wu et al. AGING CELL
- The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline
- (2019) Claudia Chini et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice
- (2019) Mitsukuni Yoshida et al. Cell Metabolism
- Boosting NAD+ with a small molecule that activates NAMPT
- (2019) Stephen J. Gardell et al. Nature Communications
- Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria
- (2019) Ceereena Ubaida-Mohien et al. eLife
- Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors
- (2018) Wenyun Lu et al. ANTIOXIDANTS & REDOX SIGNALING
- Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
- (2018) Sarah J. Mitchell et al. Cell Metabolism
- A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD + Decline
- (2018) Mariana G. Tarragó et al. Cell Metabolism
- Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
- (2018) Ling Liu et al. Cell Metabolism
- NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR
- (2018) Jun Yoshino et al. Cell Metabolism
- Organ Co-Relationship in Tryptophan Metabolism and Factors That Govern the Biosynthesis of Nicotinamide from Tryptophan
- (2018) Katsumi SHIBATA JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Alterations in energy substrate metabolism in mice with different degrees of sepsis
- (2018) Takayuki Irahara et al. JOURNAL OF SURGICAL RESEARCH
- Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
- (2018) Antonio Davila et al. eLife
- CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions
- (2018) Stephanie A. Amici et al. Frontiers in Immunology
- The Plasma NAD+ Metabolome is Dysregulated in ‘normal’ Ageing
- (2018) James Clement et al. REJUVENATION RESEARCH
- Peak Annotation and Verification Engine for Untargeted LC–MS Metabolomics
- (2018) Lin Wang et al. ANALYTICAL CHEMISTRY
- Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation
- (2018) Paras S. Minhas et al. NATURE IMMUNOLOGY
- Nicotinamide Mononucleotide, an NAD + Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1–Dependent Manner
- (2017) Yi Guan et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- NAD and the aging process: Role in life, death and everything in between
- (2017) Claudia C.S. Chini et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- SIRT3 and mitochondrial metabolism in neurodegenerative diseases
- (2017) Illari Salvatori et al. NEUROCHEMISTRY INTERNATIONAL
- Caloric restriction improves health and survival of rhesus monkeys
- (2017) Julie A. Mattison et al. Nature Communications
- The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism
- (2017) Jonathan Matalonga et al. Cell Reports
- NAD + metabolism: Bioenergetics, signaling and manipulation for therapy
- (2016) Yue Yang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
- (2016) Kathryn F. Mills et al. Cell Metabolism
- CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism
- (2016) Juliana Camacho-Pereira et al. Cell Metabolism
- NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
- (2016) H. Zhang et al. SCIENCE
- Regulation of mammalian nucleotide metabolism and biosynthesis
- (2015) Andrew N. Lane et al. NUCLEIC ACIDS RESEARCH
- In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences
- (2015) Xiao-Hong Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NAD+ in aging, metabolism, and neurodegeneration
- (2015) E. Verdin SCIENCE
- P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage
- (2014) Gelin Wang et al. CELL
- Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction
- (2014) Evandro Fei Fang et al. CELL
- A High-Fat Diet and NAD + Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome
- (2014) Morten Scheibye-Knudsen et al. Cell Metabolism
- Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase Is Not Sufficient to Promote Oxidative Metabolism
- (2014) David W. Frederick et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
- (2013) Ana P. Gomes et al. CELL
- NAD+metabolism: A therapeutic target for age-related metabolic disease
- (2013) Laurent Mouchiroud et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Nicotinamide Phosphoribosyltransferase Is Required for the Calorie Restriction-Mediated Improvements in Oxidative Stress, Mitochondrial Biogenesis, and Metabolic Adaptation
- (2013) J. Song et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The caloric restriction paradigm: Implications for healthy human aging
- (2012) Rozalyn M. Anderson et al. AMERICAN JOURNAL OF HUMAN BIOLOGY
- Sirtuins mediate mammalian metabolic responses to nutrient availability
- (2012) Angeliki Chalkiadaki et al. Nature Reviews Endocrinology
- Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue
- (2012) Hassina Massudi et al. PLoS One
- PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
- (2011) Péter Bai et al. Cell Metabolism
- Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats
- (2011) Nady Braidy et al. PLoS One
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
- Inhibition of Nicotinamide Phosphoribosyltransferase
- (2010) Maria Pittelli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Caloric restriction: From soup to nuts
- (2009) Stephen R. Spindler AGEING RESEARCH REVIEWS
- Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation
- (2009) Christian Dölle et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
- (2008) Marcella Fulco et al. DEVELOPMENTAL CELL
- Tissue-specific regulation of SIRT1 by calorie restriction
- (2008) D. Chen et al. GENES & DEVELOPMENT
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