Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes

(2013) Oliver Soehnlein et al.   EMBO Molecular Medicine

Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction

(2012) Fabrizio Montecucco et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Atherogenesis by Chemokines and Chemokine Receptors

(2012) Wuzhou Wan et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Fatty Acid Amide Hydrolase Deficiency Enhances Intraplaque Neutrophil Recruitment in Atherosclerotic Mice

(2012) Sébastien Lenglet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Conditional Targeting of Tumor Necrosis Factor Receptor–Associated Factor 6 Reveals Opposing Functions of Toll-Like Receptor Signaling in Endothelial and Myeloid Cells in a Mouse Model of Atherosclerosis

(2012) Apostolos Polykratis et al.   CIRCULATION

Multiple Roles for Neutrophils in Atherosclerosis

(2012) Oliver Soehnlein   CIRCULATION RESEARCH

Treatment with Evasin-3 Reduces Atherosclerotic Vulnerability for Ischemic Stroke, but Not Brain Injury in Mice

(2012) Jean-Christophe Copin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury

(2012) Emanuela Esposito et al.   Journal of Neuroinflammation

Chemokines: established and novel targets in atherosclerosis

(2011) Rory R. Koenen et al.   EMBO Molecular Medicine

The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques

(2011) Fabrizio Montecucco et al.   EUROPEAN HEART JOURNAL

A key role for Pre-B cell colony-enhancing factor in experimental hepatitis

(2011) Alexander R. Moschen et al.   HEPATOLOGY

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability

(2011) A. Quercioli et al.   THROMBOSIS AND HAEMOSTASIS

Single Administration of the CXC Chemokine-Binding Protein Evasin-3 During Ischemia Prevents Myocardial Reperfusion Injury in Mice

(2010) Fabrizio Montecucco et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hyperlipidemia-Triggered Neutrophilia Promotes Early Atherosclerosis

(2010) Maik Drechsler et al.   CIRCULATION

Therapeutic targeting of chemokine interactions in atherosclerosis

(2010) Rory R. Koenen et al.   NATURE REVIEWS DRUG DISCOVERY

Systemic and Intraplaque Mediators of Inflammation Are Increased in Patients Symptomatic for Ischemic Stroke

(2010) Fabrizio Montecucco et al.   STROKE

NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway

(2009) Julia Skokowa et al.   NATURE MEDICINE

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

(2009) Frédéric Van Gool et al.   NATURE MEDICINE

Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

(2009) Santina Bruzzone et al.   PLoS One

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD

(2008) Nathalie Busso et al.   PLoS One