Current view on novel vaccine technologies to combat human infectious diseases

Pandemics Throughout History

(2021) Jocelyne Piret et al.   Frontiers in Microbiology

BNT162b vaccines protect rhesus macaques from SARS-CoV-2

(2021) Annette B. Vogel et al.   NATURE

Cross-neutralization between vaccine and circulating wild-type mumps viruses in Korea

(2021) Hyeran Won et al.   VACCINE

Development of Pandemic Vaccines: ERVEBO Case Study

(2021) Jayanthi Wolf et al.   Vaccines

Vectored Immunotherapeutics for Infectious Diseases: Can rAAVs Be The Game Changers for Fighting Transmissible Pathogens?

(2021) Wei Zhan et al.   Frontiers in Immunology

Squalene-Based Influenza Vaccine Adjuvants and Their Impact on the Hemagglutinin-Specific B Cell Response

(2021) Phuong Nguyen-Contant et al.   Pathogens

Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines

(2021) Virginia Aida et al.   Frontiers in Veterinary Science

Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals

(2021) Elizabeth Fraley et al.   BMC Medicine

A single-shot Lassa vaccine induces long-term immunity and protects cynomolgus monkeys against heterologous strains

(2021) Mathieu Mateo et al.   Science Translational Medicine

Immune Evasion of SARS-CoV-2 Emerging Variants: What Have We Learnt So Far?

(2021) Ivana Lazarevic et al.   Viruses-Basel

Structural perspectives on HCV humoral immune evasion mechanisms

(2021) Madhumati Sevvana et al.   Current Opinion in Virology

Use of mRNA COVID-19 Vaccine After Reports of Myocarditis Among Vaccine Recipients: Update from the Advisory Committee on Immunization Practices — United States, June 2021

(2021) Julia W. Gargano et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Recent Advances and Future Perspectives in Polymer-Based Nanovaccines

(2021) Natassa Pippa et al.   Vaccines

Thrombosis with thrombocytopenia syndrome associated with COVID-19 vaccines

(2021) Brit Long et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

A review of alternative promoters for optimal recombinant protein expression in baculovirus-infected insect cells

(2021) Carissa Grose et al.   PROTEIN EXPRESSION AND PURIFICATION

Durability of Cross-Protection by Different Schedules of the Bivalent HPV Vaccine: the CVT Trial

(2020) Sabrina H Tsang et al.   JNCI-Journal of the National Cancer Institute

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Transposon vector-mediated stable gene transfer for the accelerated establishment of recombinant mammalian cell pools allowing for high-yield production of biologics

(2020) Natalie Tschorn et al.   BIOTECHNOLOGY LETTERS

Toll-like Receptors and the Control of Immunity

(2020) Katherine A. Fitzgerald et al.   CELL

Induction of mucosal immunity against pathogens by using recombinant baculoviral vectors: Mechanisms, advantages, and limitations

(2020) Mario Fragoso‐Saavedra et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Measles pathogenesis, immune suppression and animal models

(2020) Brigitta M Laksono et al.   Current Opinion in Virology

Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines

(2020) Lynda Coughlan   Frontiers in Immunology

Spatiotemporal dynamics of innate immune signaling via RIG-I–like receptors

(2020) Katharina Esser-Nobis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA Vaccine Era—Mechanisms, Drug Platform and Clinical Prospection

(2020) Shuqin Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of Microbiota: A Paradigm for Evolving Herd Immunity against Viral Diseases

(2020) Asha Shelly et al.   Viruses-Basel

Could “trained immunity” be induced by live attenuated vaccines protect against COVID-19? Review of available evidence

(2020) Jomana W Alsulaiman et al.   Journal of Infection in Developing Countries

Mumps Outbreaks in Vaccinated Populations—Is It Time to Re-assess the Clinical Efficacy of Vaccines?

(2020) Anna R. Connell et al.   Frontiers in Immunology

Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans

(2020) K. A. Richards et al.   npj Vaccines

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

(2020) Rinke Bos et al.   npj Vaccines

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

(2020) Maheshi N Ramasamy et al.   LANCET

Measles immunity and immunosuppression

(2020) Diane E Griffin   Current Opinion in Virology

Safety and immunogenicity of a two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Europe (EBOVAC2): a randomised, observer-blind, participant-blind, placebo-controlled, phase 2 trial

(2020) Andrew J Pollard et al.   LANCET INFECTIOUS DISEASES

Factors That Influence the Immune Response to Vaccination

(2019) Petra Zimmermann et al.   CLINICAL MICROBIOLOGY REVIEWS

Adjuvant activity of multimolecular complexes based on Glycyrrhiza glabra saponins, lipids, and influenza virus glycoproteins

(2019) P. G. Alexyuk et al.   ARCHIVES OF VIROLOGY

A comparison of EMA and FDA decisions for new drug marketing applications 2014‐2016: concordance, discordance and why

(2019) Mwango Kashoki et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens

(2019) Anahita Fathi et al.   Human Vaccines & Immunotherapeutics

Edible Vaccines: Promises and Challenges

(2019) Vrinda M Kurup et al.   MOLECULAR BIOTECHNOLOGY

Multiple roles for HIV broadly neutralizing antibodies

(2019) Barton F. Haynes et al.   Science Translational Medicine

Update on Vaccine-Derived Poliovirus Outbreaks — Worldwide, January 2018–June 2019

(2019) Jaume Jorba et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Peptide-Based Vaccines: Current Progress and Future Challenges

(2019) Ryan J. Malonis et al.   CHEMICAL REVIEWS

State‐of‐the‐art human adenovirus vectorology for therapeutic approaches

(2019) Jian Gao et al.   FEBS LETTERS

Virus-like Particle-Based L2 Vaccines against HPVs: Where Are We Today?

(2019) Rashi Yadav et al.   Viruses-Basel

Rhabdoviruses as vaccine platforms for infectious disease and cancer

(2018) Franz Zemp et al.   Biotechnology & Genetic Engineering Reviews

Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics

(2018) Sonia Gutiérrez-Granados et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

The interaction between baculoviruses and their insect hosts

(2018) Ming Kong et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Emergent lineages of mumps virus suggest the need for a polyvalent vaccine

(2018) Meghan May et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Clinical use of lentiviral vectors

(2018) Michael C. Milone et al.   LEUKEMIA

Measles-derived vaccines to prevent emerging viral diseases

(2018) Phanramphoei N. Frantz et al.   MICROBES AND INFECTION

Recent advances in mRNA vaccine delivery

(2018) Lu Tan et al.   Nano Research

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

Maximizing the translational yield of mRNA therapeutics by minimizing 5'-UTRs

(2018) Zeljka Trepotec et al.   TISSUE ENGINEERING PART A

Knowledge gaps persist and hinder progress in eliminating mumps

(2018) R. Ramanathan et al.   VACCINE

Baculovirus Surface Display of Immunogenic Proteins for Vaccine Development

(2018) Balraj Premanand et al.   Viruses-Basel

Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity

(2018) A. A. Latanova et al.   Scientific Reports

Engineering DNA vaccines against infectious diseases

(2018) Jihui Lee et al.   Acta Biomaterialia

New Vaccine Technologies to Combat Outbreak Situations

(2018) Susanne Rauch et al.   Frontiers in Immunology

Sera from different age cohorts in Belgium show limited cross-neutralization between the mumps vaccine and outbreak strains

(2018) T. Vermeire et al.   CLINICAL MICROBIOLOGY AND INFECTION

Modular core-shell polymeric nanoparticles mimicking viral structures for vaccination

(2018) Bo Lou et al.   JOURNAL OF CONTROLLED RELEASE

The changing epidemiology of mumps in a high vaccination era

(2018) Helen S Marshall et al.   LANCET INFECTIOUS DISEASES

Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins

(2018) Aitor Nogales et al.   Viruses-Basel

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding

(2018) Bruno Hernáez et al.   Nature Communications

Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems

(2017) S Guan et al.   GENE THERAPY

Worldwide burden of cancer attributable to HPV by site, country and HPV type

(2017) Catherine de Martel et al.   INTERNATIONAL JOURNAL OF CANCER

Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination

(2017) Mona O. Mohsen et al.   JOURNAL OF CONTROLLED RELEASE

Modified mRNA-Based Vaccines Elicit Robust Immune Responses and Protect Guinea Pigs From Ebola Virus Disease

(2017) Michelle Meyer et al.   JOURNAL OF INFECTIOUS DISEASES

Immunodominance of Adenovirus-Derived CD8 + T Cell Epitopes Interferes with the Induction of Transgene-Specific Immunity in Adenovirus-Based Immunization

(2017) Dominik Schöne et al.   JOURNAL OF VIROLOGY

Production of a Chikungunya Vaccine Using a CHO Cell and Attenuated Viral-Based Platform Technology

(2017) Preethi Eldi et al.   MOLECULAR THERAPY

Major findings and recent advances in virus–like particle (VLP)-based vaccines

(2017) Mona O. Mohsen et al.   SEMINARS IN IMMUNOLOGY

Targeting Pattern Recognition Receptors (PRR) for Vaccine Adjuvantation: From Synthetic PRR Agonists to the Potential of Defective Interfering Particles of Viruses

(2017) Andri Vasou et al.   Viruses-Basel

Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity

(2017) John J. Suschak et al.   Human Vaccines & Immunotherapeutics

Editorial: Danger Signals Triggering Immune Response and Inflammation

(2017) Abdulraouf Ramadan et al.   Frontiers in Immunology

An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

(2017) Jasdave S. Chahal et al.   Scientific Reports

Prevention of cervical cancer: journey to develop the first human papillomavirus virus-like particle vaccine and the next generation vaccine

(2016) Janine T Bryan et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Recent innovations in mRNA vaccines

(2016) Jeffrey B Ulmer et al.   CURRENT OPINION IN IMMUNOLOGY

Why don’t we have an effective tuberculosis vaccine yet?

(2016) Tamara Davenne et al.   Expert Review of Vaccines

Adjuvant system AS01: helping to overcome the challenges of modern vaccines

(2016) Arnaud M. Didierlaurent et al.   Expert Review of Vaccines

Incorporation of a Nuclear Localization Signal in pH Responsive LAH4-L1 Peptide Enhances Transfection and Nuclear Uptake of Plasmid DNA

(2016) Yingying Xu et al.   MOLECULAR PHARMACEUTICS

Codon optimization of antigen coding sequences improves the immune potential of DNA vaccines against avian influenza virus H5N1 in mice and chickens

(2016) Anna Stachyra et al.   Virology Journal

Peptide-based synthetic vaccines

(2016) Mariusz Skwarczynski et al.   Chemical Science

An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs

(2016) Margit Schnee et al.   PLoS Neglected Tropical Diseases

Recent advances in the production of recombinant subunit vaccines inPichia pastoris

(2016) Man Wang et al.   Bioengineered

Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials

(2016) Timothy Weixin Kwang et al.   Molecular Therapy-Methods & Clinical Development

The baculovirus expression vector system: A commercial manufacturing platform for viral vaccines and gene therapy vectors

(2015) Rachael S. Felberbaum   Biotechnology Journal

Nanoparticles as synthetic vaccines

(2015) Josiah D Smith et al.   CURRENT OPINION IN BIOTECHNOLOGY

Measles 50 Years After Use of Measles Vaccine

(2015) James L. Goodson et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Identification of conformational neutralization sites on the fusion protein of mumps virus

(2015) Maja Šantak et al.   JOURNAL OF GENERAL VIROLOGY

Accumulation of defective interfering viral particles in only a few passages in Vero cells attenuates mumps virus neurovirulence

(2015) Maja Šantak et al.   MICROBES AND INFECTION

Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals

(2015) Andreas Thess et al.   MOLECULAR THERAPY

The baculovirus expression vector system: A commercial manufacturing platform for viral vaccines and gene therapy vectors

(2015) Rachael S. Felberbaum   Biotechnology Journal

Mannose derivative and lipid A dually decorated cationic liposomes as an effective cold chain free oral mucosal vaccine adjuvant-delivery system

(2014) Ning Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens

(2014) Shih-Yeh Lin et al.   Expert Review of Vaccines

Self-replicating alphavirus RNA vaccines

(2014) Karl Ljungberg et al.   Expert Review of Vaccines

Thirty years of baculovirus-insect cell protein expression: from dark horse to mainstream technology

(2014) M. M. van Oers et al.   JOURNAL OF GENERAL VIROLOGY

Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques

(2014) R. Halwani et al.   JOURNAL OF IMMUNOLOGY

History of vaccination

(2014) S. Plotkin   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of IFN-α Subtypes and Their Antiviral Activity in Mumps Virus Infection

(2014) Maja Markušić et al.   VIRAL IMMUNOLOGY

Bioreducible alginate-poly(ethylenimine) nanogels as an antigen-delivery system robustly enhance vaccine-elicited humoral and cellular immune responses

(2013) Ping Li et al.   JOURNAL OF CONTROLLED RELEASE

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

(2013) G. L. Smith et al.   JOURNAL OF GENERAL VIROLOGY

Toll-Like Receptors in Antiviral Innate Immunity

(2013) Sandra N. Lester et al.   JOURNAL OF MOLECULAR BIOLOGY

Single low-dose un-adjuvanted HBsAg nanoparticle vaccine elicits robust, durable immunity

(2013) Amit A. Lugade et al.   Nanomedicine-Nanotechnology Biology and Medicine

Seroprevalence of Mumps in The Netherlands: Dynamics over a Decade with High Vaccination Coverage and Recent Outbreaks

(2013) Gaby Smits et al.   PLoS One

Modified Vaccinia virus Ankara: Innate immune activation and induction of cellular signalling

(2013) Philip J.R. Price et al.   VACCINE

Nanoparticle vaccines

(2013) Liang Zhao et al.   VACCINE

Interleukin-12 as a genetic adjuvant enhances hepatitis C virus NS3 DNA vaccine immunogenicity

(2013) Malihe Naderi et al.   VIROLOGICA SINICA

Recombinant vaccines and the development of new vaccine strategies

(2012) I.P. Nascimento et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Antigenic differences between vaccine and circulating wild-type mumps viruses decreases neutralization capacity of vaccine-induced antibodies

(2012) M. ŠANTAK et al.   EPIDEMIOLOGY AND INFECTION

The role of liposome size on the type of immune response induced in BALB/c mice against leishmaniasis: rgp63 as a model antigen

(2012) Ali Badiee et al.   EXPERIMENTAL PARASITOLOGY

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Innate Immunity Mediates Follicular Transport of Particulate but Not Soluble Protein Antigen

(2012) A. Link et al.   JOURNAL OF IMMUNOLOGY

The origins of inoculation

(2012) Arthur Boylston   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Autoimmunity following Hepatitis B vaccine as part of the spectrum of ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’ (ASIA): analysis of 93 cases

(2012) Y Zafrir et al.   LUPUS

Nonviral delivery of self-amplifying RNA vaccines

(2012) A. J. Geall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Horizontal transmission of the Leningrad–Zagreb mumps vaccine strain: A report of six symptomatic cases of parotitis and one case of meningitis

(2012) Alina Atrasheuskaya et al.   VACCINE

Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

(2012) Douglas S. Watson et al.   VACCINE

Nonclinical phenotypic and genotypic analyses of a Phase 1 pediatric respiratory syncytial virus vaccine candidate MEDI-559 (rA2cp248/404/1030ΔSH) at permissive and non-permissive temperatures

(2012) Jeanne H. Schickli et al.   VIRUS RESEARCH

Vaccines: From Empirical Development to Rational Design

(2012) Christine Rueckert et al.   PLoS Pathogens

Development and Applications of VSV Vectors Based on Cell Tropism

(2012) Hideki Tani et al.   Frontiers in Microbiology

Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-like Particles

(2011) Carlee E. Ashley et al.   ACS Nano

Hyaluronic acid hydrogel particles with tunable charges as potential drug delivery devices

(2011) Sema Ekici et al.   CARBOHYDRATE POLYMERS

"Herd Immunity": A Rough Guide

(2011) P. Fine et al.   CLINICAL INFECTIOUS DISEASES

MVA and NYVAC as Vaccines against Emergent Infectious Diseases and Cancer

(2011) Carmen E. Gomez et al.   CURRENT GENE THERAPY

Mumps Antibody Levels Among Students Before a Mumps Outbreak: In Search of a Correlate of Immunity

(2011) M. M. Cortese et al.   JOURNAL OF INFECTIOUS DISEASES

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

(2011) Katalin Karikó et al.   NUCLEIC ACIDS RESEARCH

Progress in understanding adjuvant immunotoxicity mechanisms

(2011) Alexander Batista-Duharte et al.   TOXICOLOGY LETTERS

Baculovirus Gene Delivery: A Flexible Assay Development Tool

(2010) Thomas A. Kost et al.   CURRENT GENE THERAPY

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

How RNA viruses maintain their genome integrity

(2010) J. N. Barr et al.   JOURNAL OF GENERAL VIROLOGY

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

(2010) Freya J. I. Fowkes et al.   PLOS MEDICINE

The Interferon System and Vaccinia Virus Evasion Mechanisms

(2009) Beatriz Perdiguero et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

Codon stabilization analysis of the “248” temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates

(2009) Cindy Luongo et al.   VACCINE

Vaccination greatly reduces disease, disability, death and inequity worldwide

(2008) FE Andre et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

DNA vaccines: developing new strategies to enhance immune responses

(2008) Shaheed A. Abdulhaqq et al.   IMMUNOLOGIC RESEARCH

Variability of hemagglutinin-neuraminidase and nucleocapsid protein of vaccine and wild-type mumps virus strains

(2008) Jelena Ivancic-Jelecki et al.   INFECTION GENETICS AND EVOLUTION

Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

(2008) Katalin Karikó et al.   MOLECULAR THERAPY

Horizontal transmission of the Leningrad–Zagreb mumps vaccine strain: A report of three cases

(2008) Goran Tešović et al.   VACCINE

The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods

(2008) Shixia Wang et al.   VACCINE

Plasmid DNA loaded chitosan nanoparticles for nasal mucosal immunization against hepatitis B

(2007) Kapil Khatri et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS