Pharmacological Activities for Morus alba L., Focusing on the Immunostimulatory Property from the Fruit Aqueous Extract

Antioxidant and Anti-Inflammatory Effects of White Mulberry (Morus alba L.) Fruits on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

(2021) Jae Sik Yu et al.   MOLECULES

Nutritional constituents of mulberry and their potential applications in food and pharmaceuticals: A review

(2021) Bisma Jan et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Structural, rheological properties and antioxidant activities of polysaccharides from mulberry fruits (Murus alba L.) based on different extraction techniques with superfine grinding pretreatment

(2021) Mo Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Arginase inhibitory properties of flavonoid compounds from the leaves of Mulberry ( Morus alba , Moraceae)

(2020) Kamel Arraki et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Mulberry Fruit Extract Alleviates Cognitive Impairment by Promoting the Clearance of Amyloid-β and Inhibiting Neuroinflammation in Alzheimer’s Disease Mice

(2020) Dianxun Liu et al.   NEUROCHEMICAL RESEARCH

Comparative Study of the Antioxidant and Anti-Inflammatory Effects of Leaf Extracts from Four Different Morus alba Genotypes in High Fat Diet-Induced Obesity in Mice

(2020) Francisco Javier Leyva-Jiménez et al.   Antioxidants

Phenolic constituents and anticancer properties of Morus alba (white mulberry) leaves

(2020) Eric Wei Chiang Chan et al.   Journal of Integrative Medicine-JIM

Protective role of fermented mulberry leave extract in LPS‑induced inflammation and autophagy of RAW264.7 macrophage cells

(2020) Mi Lee et al.   Molecular Medicine Reports

Optimization and characterization of eco‐friendly antimicrobial nanocellulose sheet prepared using carbon dots of white mulberry ( Morus alba L.)

(2020) Fatemeh Salimi et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Mulberry leaf polysaccharide supplementation contributes to enhancing the respiratory mucosal barrier immune response in Newcastle disease virus–vaccinated chicks

(2020) Xiaolan Chen et al.   POULTRY SCIENCE

Nutraceutical and Medicinal Potential of the Morus Species in Metabolic Dysfunctions

(2019) Elisana Rodrigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Purification, characterization and in vitro and in vivo immune enhancement of polysaccharides from mulberry leaves

(2019) Xiaolan Chen et al.   PLoS One

The Root Bark of Morus alba L. Suppressed the Migration of Human Non-Small-Cell Lung Cancer Cells through Inhibition of Epithelial–Mesenchymal Transition Mediated by STAT3 and Src

(2019) Tae-Rin Min et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds

(2019) Igor A. Schepetkin et al.   MOLECULES

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

Immunotherapeutic Approaches for the Treatment of Colorectal Cancer

(2019) E. V. Abakushina et al.   BIOCHEMISTRY-MOSCOW

Flavonoids from Morus alba L. Leaves: Optimization of Extraction by Response Surface Methodology and Comprehensive Evaluation of Their Antioxidant, Antimicrobial, and Inhibition of α-Amylase Activities through Analytical Hierarchy Process

(2019) Hao Cui et al.   MOLECULES

Polysaccharide from Mulberry Fruit (Morus alba L.) Protects against Palmitic-Acid-Induced Hepatocyte Lipotoxicity by Activating the Nrf2/ARE Signaling Pathway

(2019) Dongwen Hu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Comparative Study on the Phenolic Composition and Biological Activities of Morus alba L. Commercial Samples

(2019) Milena Polumackanycz et al.   MOLECULES

Morus alba (mulberry), a natural potent compound in management of obesity

(2019) Mohaddese Mahboubi   PHARMACOLOGICAL RESEARCH

Effects of astragalus and ginseng polysaccharides on growth performance, immune function and intestinal barrier in weaned piglets challenged with lipopolysaccharide

(2019) Kangli Wang et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Mulberry fruit improves memory in scopolamine-treated mice: role of cholinergic function, antioxidant system, and TrkB/Akt signaling

(2019) Suk Kyung Shin et al.   NUTRITIONAL NEUROSCIENCE

Natural products, extracts and formulations comprehensive therapy for the improvement of motor function in alcoholic liver disease

(2019) Shuang Hu et al.   PHARMACOLOGICAL RESEARCH

Protective effect of black mulberry (Morus nigra L.) fruit hydroalcoholic extract against testosterone-induced benign prostatic hyperplasia in rats

(2019) Mohammad Ali Farshid et al.   Revista Internacional de Andrologia

Effects of an ethanolic extract of mulberry fruit on blood pressure and vascular remodeling in spontaneous hypertensive rats

(2018) Sang Woong Park et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay

(2018) Ming Hong et al.   Evidence-based Complementary and Alternative Medicine

Comparison of the protective effect of black and white mulberry against ethyl carbamate-induced cytotoxicity and oxidative damage

(2018) Yuting Li et al.   FOOD CHEMISTRY

Structures, bioactivities and future prospective of polysaccharides from Morus alba (white mulberry): A review

(2018) Xirui He et al.   FOOD CHEMISTRY

Systematic fractionation and immunoenhancement of water-soluble polysaccharides isolated from fruit of Morus alba L.

(2018) DongXue Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Beneficial Effects of Bioactive Compounds in Mulberry Fruits against Cisplatin-Induced Nephrotoxicity

(2018) Dahae Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical scavenging profiling combined with high-performance liquid chromatography–high-resolution mass spectrometry–solid-phase extraction–nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude root bark of Morus alba L.

(2018) Yong Zhao et al.   JOURNAL OF CHROMATOGRAPHY A

Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress

(2018) Chiung-Huei Peng et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Effective Combination Adjuvants Engage Both TLR and Inflammasome Pathways To Promote Potent Adaptive Immune Responses

(2018) Emilie Seydoux et al.   JOURNAL OF IMMUNOLOGY

A Chemical Investigation of the Leaves of Morus alba L.

(2018) Xiao-yan Chen et al.   MOLECULES

Survey of the effect of doxorubicin and flavonoid extract of white Morus alba leaf on apoptosis induction in a-172 GBM cell line

(2018) Sheyda Dabili et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Vascular Protection by Ethanol Extract of Morus alba Root Bark: Endothelium-Dependent Relaxation of Rat Aorta and Decrease of Smooth Muscle Cell Migration and Proliferation

(2018) Nisha Panth et al.   Evidence-based Complementary and Alternative Medicine

Monocytes in rheumatoid arthritis: Circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis

(2018) Amit Kumar Rana et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metabolism Plays a Key Role during Macrophage Activation

(2018) Marion I. Stunault et al.   MEDIATORS OF INFLAMMATION

Morus alba leaf extract mediates neuroprotection against glyphosate-induced toxicity and biochemical alterations in the brain

(2017) Olfa Rebai et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

In Vitro Anti-Inflammatory Activity of Morus alba L. Stem Extract in LPS-Stimulated RAW 264.7 Cells

(2017) Nattaporn Soonthornsit et al.   Evidence-based Complementary and Alternative Medicine

Chemical Constituents with Proprotein Convertase Subtilisin/Kexin Type 9 mRNA Expression Inhibitory Activity from Dried Immature Morus alba Fruits

(2017) Pisey Pel et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Mulberry (Morus alba L.) Fruit—A Review of Characteristic Components and Health Benefits

(2017) Qingxia Yuan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats

(2017) Yukun Jiao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Thermal and Antioxidant Properties of Polysaccharides Sequentially Extracted from Mulberry Leaves (Morus alba L.)

(2017) Bu-Yan Liao et al.   MOLECULES

Mulberry Fruit Extract Affords Protection against Ethyl Carbamate-Induced Cytotoxicity and Oxidative Stress

(2017) Wei Chen et al.   Oxidative Medicine and Cellular Longevity

Phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity in vitro

(2017) Xiao-Ke Zheng et al.   PHYTOCHEMISTRY

Characterization of Phenolic Constituents from Ephedra Herb Extract

(2017) Yoshiaki Amakura   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

The involvement of ginseng berry extract in blood flow via regulation of blood coagulation in rats fed a high-fat diet

(2017) Min Hee Kim et al.   Journal of Ginseng Research

Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect

(2017) Thomas Sithara et al.   Frontiers in Pharmacology

Extraction, separation and characterization of endotoxins in water samples using solid phase extraction and capillary electrophoresis-laser induced fluorescence

(2017) Fun Man Fung et al.   Scientific Reports

The Effects of Supplementary Mulberry Leaf (Morus alba) Extracts on the Trace Element Status (Fe, Zn and Cu) in Relation to Diabetes Management and Antioxidant Indices in Diabetic Rats

(2016) Ewelina Król et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

New potential phytotherapeutics obtained from white mulberry ( Morus alba L.) leaves

(2016) Anna Gryn-Rynko et al.   BIOMEDICINE & PHARMACOTHERAPY

Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.)

(2016) Ji Won Choi et al.   CARBOHYDRATE POLYMERS

Consumption of polyphenol-rich Morus alba leaves extract attenuates early diabetic retinopathy: the underlying mechanism

(2016) Ayman M. Mahmoud et al.   EUROPEAN JOURNAL OF NUTRITION

Protective Effect of Morus alba Leaf Extract on N-Nitrosodiethylamine-induced Hepatocarcinogenesis in Rats

(2016) MAŁGORZATA KUJAWSKA et al.   IN VIVO

A 28-Day Repeated Dose Toxicological Study of an Aqueous Extract of Morus Alba L.

(2016) Tennille K. Marx et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Odisolane, a Novel Oxolane Derivative, and Antiangiogenic Constituents from the Fruits of Mulberry (Morus alba L.)

(2016) Seoung Rak Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Evaluation of acute toxicity, genotoxicity and inhibitory effect on acute inflammation of an ethanol extract of Morus alba L. (Moraceae) in mice

(2016) Alisson Macário de Oliveira et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nonclinical Safety Assessment ofMorus alba L. Fruits: Study of 90-D Toxicity in Sprague Dawley Rats and Genotoxicity inSalmonella

(2016) Bo Yoon Chang et al.   JOURNAL OF FOOD SCIENCE

Combined Mulberry Leaf and Fruit Extract Improved Early Stage of Cutaneous Wound Healing in High-Fat Diet-Induced Obese Mice

(2016) Hyeyoon Eo et al.   JOURNAL OF MEDICINAL FOOD

Mulberry (Morus alba L.) Fruit Extract Containing Anthocyanins Improves Glycemic Control and Insulin Sensitivity via Activation of AMP-Activated Protein Kinase in Diabetic C57BL/Ksj-db/db Mice

(2016) Kyung Ha Choi et al.   JOURNAL OF MEDICINAL FOOD

In vitro and In vivo antioxidant activity of flavonoid extracted from mulberry fruit (Morus alba L.)

(2016) Zhongzheng Gui et al.   Pharmacognosy Magazine

Morus alba L. Stem Extract Attenuates Pain and Articular Cartilage Damage in the Anterior Cruciate Ligament Transection-Induced Rat Model of Osteoarthritis

(2016) Arada Khunakornvichaya et al.   PHARMACOLOGY

Purinergic Signaling to Terminate TLR Responses in Macrophages

(2016) Kajal Hamidzadeh et al.   Frontiers in Immunology

Chemical properties in fruits of mulberry species from the Xinjiang province of China

(2015) Yan Jiang et al.   FOOD CHEMISTRY

Analysis and characterisation of phytochemicals in mulberry (Morus alba L.) fruits grown in Vojvodina, North Serbia

(2015) Maja M. Natić et al.   FOOD CHEMISTRY

Extraction characteristics of subcritical water depending on the number of hydroxyl group in flavonols

(2015) Chan-Ick Cheigh et al.   FOOD CHEMISTRY

Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

(2015) Ji-Young Ann et al.   Genes and Nutrition

Improved Chemotherapeutic Activity by Morus alba Fruits through Immune Response of Toll-Like Receptor 4

(2015) Bo Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective Effect of Prenylated Arylbenzofuran and Flavonoids fromMorus albaFruits on Glutamate-Induced Oxidative Injury in HT22 Hippocampal Cells

(2015) Kyeong-Hwa Seo et al.   JOURNAL OF MEDICINAL FOOD

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

(2015) Ji-Young Ann et al.   Genes and Nutrition

Ecdysteroids Regulate the Levels of Molt-Inhibiting Hormone (MIH) Expression in the Blue Crab, Callinectes sapidus

(2015) Sirinart Techa et al.   PLoS One

Pyrrole alkaloids from the fruits of Morus alba

(2014) Seon Beom Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark

(2014) Hyun Ji Eo et al.   BMC Complementary and Alternative Medicine

The Potential Role of Morus Alba Leaves Extract on the Brain of Mice Infected with Schistosoma Mansoni

(2014) Amira Bauomy   CNS & Neurological Disorders-Drug Targets

Antiplatelet Activity ofMorus albaLeaves Extract, Mediated via Inhibiting Granule Secretion and Blocking the Phosphorylation of Extracellular-Signal-Regulated Kinase and Akt

(2014) Dong-Seon Kim et al.   Evidence-based Complementary and Alternative Medicine

Polyphenols from the stems of Morus alba and their inhibitory activity against nitric oxide production by lipopolysaccharide-activated microglia

(2014) Céline Rivière et al.   FITOTERAPIA

Reduction of adenovirus 36-induced obesity and inflammation by mulberry extract

(2014) Ha-Na Na et al.   MICROBIOLOGY AND IMMUNOLOGY

Effect of Kuwanon G Isolated from the Root Bark ofMorus albaon Ovalbumin-induced Allergic Response in a Mouse Model of Asthma

(2014) Hyo Won Jung et al.   PHYTOTHERAPY RESEARCH

White Mulberry (Morus alba) Foliage Methanolic Extract Can AlleviateAeromonas hydrophilaInfection in African Catfish (Clarias gariepinus)

(2014) Atefeh Sheikhlar et al.   TheScientificWorldJOURNAL

Dual inhibition of arachidonic acid pathway by mulberry leaf extract

(2014) Seema Chauhan et al.   INFLAMMOPHARMACOLOGY

Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK/ERK signaling

(2013) Yi-Ching Chen et al.   BMC Complementary and Alternative Medicine

Metabolic Effects of Mulberry Leaves: Exploring Potential Benefits in Type 2 Diabetes and Hyperuricemia

(2013) A. Hunyadi et al.   Evidence-based Complementary and Alternative Medicine

Purification, characterization and immunomodulating activity of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.)

(2013) Ji Sun Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antidiabetic and Antioxidant Effects and Phytochemicals of Mulberry Fruit (Morus alba L.) Polyphenol Enhanced Extract

(2013) Yihai Wang et al.   PLoS One

Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats

(2013) ARIYA SARIKAPHUTI et al.   Experimental and Therapeutic Medicine

In Vitro Antioxidant and Antimicrobial Activity of Extracts from Morus alba L. Leaves, Stems and Fruits

(2012) Wei Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Promoting effect of polysaccharide isolated from Mori fructus on dendritic cell maturation

(2012) Bo Ram Shin et al.   FOOD AND CHEMICAL TOXICOLOGY

Effect of Maturity on Phenolics (Phenolic Acids and Flavonoids) Profile of Strawberry Cultivars and Mulberry Species from Pakistan

(2012) Tahir Mahmood et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant Activity of Mulberry Fruit Extracts

(2012) Muhammad Arfan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Morusinol Extracted from Morus Alba Inhibits Arterial Thrombosis and Modulates Platelet Activation for the Treatment of Cardiovascular Disease

(2012) Jung-Jin Lee et al.   Journal of Atherosclerosis and Thrombosis

Macrophage activating activity of pyrrole alkaloids from Morus alba fruits

(2012) Seon Beom Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

New triterpenoids fromMorus albaL. stem bark

(2012) Abuzer Ali et al.   NATURAL PRODUCT RESEARCH

In vitroAnti-diabetic Activity and Chemical Characterization of an Apolar Fraction ofMorus albaLeaf Water Extract

(2012) Attila Hunyadi et al.   PHYTOTHERAPY RESEARCH

Chlorogenic Acid and Rutin Play a Major Role in the In Vivo Anti-Diabetic Activity of Morus alba Leaf Extract on Type II Diabetic Rats

(2012) Attila Hunyadi et al.   PLoS One

Mulberry Water Extracts Possess an Anti-obesity Effect and Ability To Inhibit Hepatic Lipogenesis and Promote Lipolysis

(2011) Chiung-Huei Peng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Determination of iminosugars in mulberry leaves and silkworms using hydrophilic interaction chromatography–tandem mass spectrometry

(2010) Kiyotaka Nakagawa et al.   ANALYTICAL BIOCHEMISTRY

Albanol A from the Root Bark of Morus alba L. Induces Apoptotic Cell Death in HL60 Human Leukemia Cell Line

(2010) Takashi Kikuchi et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Chemical composition and antioxidant activity of certain Morus species

(2010) Mohammad Imran et al.   Journal of Zhejiang University-SCIENCE B

Postprandial hypoglycemic effect of mulberry leaf in Goto-Kakizaki rats and counterpart control Wistar rats

(2010) Ji Min Park et al.   Nutrition Research and Practice

Anti-dopaminergic effect of the methanolic extract of Morus alba L. leaves

(2009) VandanaS Nade et al.   INDIAN JOURNAL OF PHARMACOLOGY

Phytochemical Profiles of Different Mulberry (Morussp.) Species from China

(2009) Wei Song et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antimicrobial activity of the methanolic extract and compounds from Morus mesozygia stem bark

(2009) V. Kuete et al.   JOURNAL OF ETHNOPHARMACOLOGY

Toll-like receptor 4-mediated immunoregulation by the aqueous extract ofMori Fructus

(2009) Xin-Ying Yang et al.   PHYTOTHERAPY RESEARCH

Assessment of herbal medicinal products: Challenges, and opportunities to increase the knowledge base for safety assessment

(2009) Scott A. Jordan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Novel anti-adherence activity of mulberry leaves: inhibition of Streptococcus mutans biofilm by 1-deoxynojirimycin isolated from Morus alba

(2008) B. Islam et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Endothelium-independent relaxation and contraction of rat aorta induced by ethyl acetate extract from leaves of Morus alba (L.)

(2008) Manli Xia et al.   JOURNAL OF ETHNOPHARMACOLOGY