Immunotherapeutic Approaches for the Treatment of Colorectal Cancer

Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer

(2019) Hadar Reichman et al.   Cancer Immunology Research

The capability and potential of new forms of personalized colon cancer treatment: Immunotherapy and Photodynamic Therapy

(2019) Marta Kaleta-Richter et al.   Photodiagnosis and Photodynamic Therapy

Mechanisms of Resistance to PD-1 and PD-L1 Blockade

(2018) Theodore S. Nowicki et al.   CANCER JOURNAL

PD-1/ PD-L1 blockade as a novel treatment for colorectal cancer

(2018) Neda Yaghoubi et al.   BIOMEDICINE & PHARMACOTHERAPY

Primary and acquired resistance to PD-1/PD-L1 blockade in cancer treatment

(2017) Qiaohong Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

(2017) Michael J Overman et al.   LANCET ONCOLOGY

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

(2017) Alice O. Kamphorst et al.   SCIENCE

Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes

(2017) Lucas A. Horn et al.   Cancer Immunology Research

PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?

(2017) Zijun Y. Xu-Monette et al.   Frontiers in Immunology

Xenogeneic cell-based vaccine therapy for colorectal cancer: Safety, association of clinical effects with vaccine-induced immune responses

(2016) G.V. Seledtsova et al.   BIOMEDICINE & PHARMACOTHERAPY

Advances in targeted and immunobased therapies for colorectal cancer in the genomic era

(2016) Heng Seow et al.   OncoTargets and Therapy

Phase I/II study of adjuvant immunotherapy with sentinel lymph node T lymphocytes in patients with colorectal cancer

(2015) Yun-Huan Zhen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

In vitro immunomodulatory properties of gemcitabine alone and in combination with interferon-alpha

(2015) Jasmin Fritz et al.   IMMUNOLOGY LETTERS

Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses

(2015) Norman Woller et al.   MOLECULAR THERAPY

Colorectal carcinogenesis-update and perspectives

(2015) Hans Raskov   WORLD JOURNAL OF GASTROENTEROLOGY

Bevacizumab exposure beyond first disease progression in patients with metastatic colorectal cancer: analyses of the ARIES observational cohort study

(2014) Axel Grothey et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Recent insights into the role of the PD-1/PD-L1 pathway in immunological tolerance and autoimmunity

(2013) Elena Gianchecchi et al.   AUTOIMMUNITY REVIEWS

Phase I trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma

(2013) Marijo Bilusic et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Gemcitabine, Oxaliplatin, Levofolinate, 5-Fluorouracil, Granulocyte-Macrophage Colony-Stimulating Factor, and Interleukin-2 (GOLFIG) Versus FOLFOX Chemotherapy in Metastatic Colorectal Cancer Patients

(2013) Pierpaolo Correale et al.   JOURNAL OF IMMUNOTHERAPY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Simultaneous Blockade of Multiple Immune System Inhibitory Checkpoints Enhances Antitumor Activity Mediated by Interleukin-15 in a Murine Metastatic Colon Carcinoma Model

(2010) P. Yu et al.   CLINICAL CANCER RESEARCH

Phase I/II Study of Oncolytic Herpes Simplex Virus NV1020 in Patients with Extensively Pretreated Refractory Colorectal Cancer Metastatic to the Liver

(2010) Sunil K. Geevarghese et al.   HUMAN GENE THERAPY

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

(2010) Richard A Morgan et al.   MOLECULAR THERAPY

T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis

(2010) Maria R Parkhurst et al.   MOLECULAR THERAPY

Development of Ipilimumab: Contribution to a New Paradigm for Cancer Immunotherapy

(2010) Axel Hoos et al.   SEMINARS IN ONCOLOGY