From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
Authors
Keywords
Lipid nanoparticles, mRNA, Vaccines, COVID-19
Journal
Acta Biomaterialia
Volume 131, Issue -, Pages 16-40
Publisher
Elsevier BV
Online
2021-06-18
DOI
10.1016/j.actbio.2021.06.023
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Proof-of-concept of a low-dose unmodified mRNA-based rabies vaccine formulated with lipid nanoparticles in human volunteers: A phase 1 trial
- (2021) Cassandra Aldrich et al. VACCINE
- Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies
- (2021) Dami A. Collier et al. NATURE
- Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing
- (2021) Shuai Liu et al. NATURE MATERIALS
- Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera
- (2021) Xuping Xie et al. NATURE MEDICINE
- Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity
- (2021) Mai N. Vu et al. Advanced Healthcare Materials
- Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein
- (2021) Nigel Davies et al. Molecular Therapy-Nucleic Acids
- Transdermal Immunization of Elastic Liposome-Laden Recombinant Chimeric Fusion Protein of P. falciparum (PfMSP-Fu24) Mounts Protective Immune Response
- (2021) Ramesh Chaudhari et al. Nanomaterials
- SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera
- (2021) Alona Kuzmina et al. Cell Host & Microbe
- Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants
- (2021) Laith J. Abu-Raddad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines
- (2021) Thai Thanh Hoang Thi et al. Vaccines
- Tuning liposome composition to modulate the corona forming in human serum and uptake by cells
- (2020) Keni Yang et al. Acta Biomaterialia
- Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway
- (2020) Yusuke Sato et al. JOURNAL OF CONTROLLED RELEASE
- The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution
- (2020) Takashi Nakamura et al. MOLECULAR PHARMACEUTICS
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
- (2020) Siddharth Patel et al. Nature Communications
- Lipid‐Modified Aminoglycosides for mRNA Delivery to the Liver
- (2020) Xueliang Yu et al. Advanced Healthcare Materials
- The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation
- (2020) Thai Thanh Hoang Thi et al. Polymers
- Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives
- (2020) Itziar Gómez-Aguado et al. Nanomaterials
- Opportunities and Challenges in the Delivery of mRNA-Based Vaccines
- (2020) Abishek Wadhwa et al. Pharmaceutics
- Engineering Caveolae-Targeted Lipid Nanoparticles To Deliver mRNA to the Lungs
- (2020) Qing Li et al. ACS Chemical Biology
- Advancements in prophylactic and therapeutic nanovaccines
- (2020) Prateek Bhardwaj et al. Acta Biomaterialia
- Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery
- (2020) Yulia Eygeris et al. NANO LETTERS
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver
- (2020) Lei Miao et al. Nature Communications
- Immunogenicity of a DNA vaccine candidate for COVID-19
- (2020) Trevor R. F. Smith et al. Nature Communications
- Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
- (2020) Eun Kim et al. EBioMedicine
- mRNA Vaccines Encoding the HA Protein of Influenza A H1N1 Virus Delivered by Cationic Lipid Nanoparticles Induce Protective Immune Responses in Mice
- (2020) Xinyu Zhuang et al. Vaccines
- Dawn of lipid nanoparticles in lymph node targeting: Potential in cancer immunotherapy
- (2020) Takashi Nakamura et al. ADVANCED DRUG DELIVERY REVIEWS
- Controlling timing and location in vaccines
- (2020) Darrell J. Irvine et al. ADVANCED DRUG DELIVERY REVIEWS
- The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease
- (2020) Guillermo Oliver et al. CELL
- A Thermostable mRNA Vaccine against COVID-19
- (2020) Na-Na Zhang et al. CELL
- Recent advances in mRNA vaccine technology
- (2020) Norbert Pardi et al. CURRENT OPINION IN IMMUNOLOGY
- Targeting immune cells within lymph nodes
- (2020) Christopher J. H. Porter et al. Nature Nanotechnology
- Programmable multistage drug delivery to lymph nodes
- (2020) Alex Schudel et al. Nature Nanotechnology
- Biological functions of lymphatic vessels
- (2020) Tatiana V. Petrova et al. SCIENCE
- Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice
- (2020) Paul F. McKay et al. Nature Communications
- Self-amplifying RNA vaccines for infectious diseases
- (2020) Kristie Bloom et al. GENE THERAPY
- Structural analysis reveals TLR7 dynamics underlying antagonism
- (2020) Shingo Tojo et al. Nature Communications
- Preparation of cetyl palmitate-based PEGylated solid lipid nanoparticles by microfluidic technique
- (2020) Ilaria Arduino et al. Acta Biomaterialia
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- Manufacturing Considerations for the Development of Lipid Nanoparticles Using Microfluidics
- (2020) Carla B. Roces et al. Pharmaceutics
- Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life
- (2019) Zeljka Trepotec et al. RNA
- Combined vaccines for prophylaxis of infectious conditions
- (2019) Pravin Shende et al. Artificial Cells Nanomedicine and Biotechnology
- RNA-based adjuvant CV8102 enhances the immunogenicity of a licensed rabies vaccine in a first-in-human trial
- (2019) Fatma Doener et al. VACCINE
- mRNA: A Novel Avenue to Antibody Therapy?
- (2019) Thomas Schlake et al. MOLECULAR THERAPY
- mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases
- (2019) Giulietta Maruggi et al. MOLECULAR THERAPY
- How mRNA therapeutics are entering the monoclonal antibody field
- (2019) Lien Van Hoecke et al. Journal of Translational Medicine
- A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer
- (2019) Martin Sebastian et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Cancer DNA vaccines: current preclinical and clinical developments and future perspectives
- (2019) Alessandra Lopes et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials
- (2019) Robert A. Feldman et al. VACCINE
- Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
- (2019) Kimberly J. Hassett et al. Molecular Therapy-Nucleic Acids
- A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
- (2019) Markus Baiersdörfer et al. Molecular Therapy-Nucleic Acids
- Material design for lymph node drug delivery
- (2019) Alex Schudel et al. Nature Reviews Materials
- Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA
- (2019) Anna K. Blakney et al. GENE THERAPY
- A Comparison of Plasmid DNA and mRNA as Vaccine Technologies
- (2019) Liu Vaccines
- A trans-amplifying RNA vaccine strategy for induction of potent protective immunity
- (2019) Tim Beissert et al. MOLECULAR THERAPY
- Three decades of messenger RNA vaccine development
- (2019) Rein Verbeke et al. Nano Today
- Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles
- (2019) Yusuke Sato et al. Acta Biomaterialia
- Tailoring mRNA Vaccine to Balance Innate/Adaptive Immune Response
- (2019) Sergio Linares-Fernández et al. TRENDS IN MOLECULAR MEDICINE
- Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells
- (2019) Marco Maugeri et al. Nature Communications
- Comparison of DNA and mRNA vaccines against cancer
- (2019) Zohreh Jahanafrooz et al. DRUG DISCOVERY TODAY
- Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening
- (2019) Pedro P.G. Guimaraes et al. JOURNAL OF CONTROLLED RELEASE
- On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA
- (2018) Jayesh A. Kulkarni et al. ACS Nano
- Fluorescence Correlation Spectroscopy to find the critical balance between extracellular association and intracellular dissociation of mRNA complexes
- (2018) Heyang Zhang et al. Acta Biomaterialia
- Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles
- (2018) Jacob W. Myerson et al. ADVANCED MATERIALS
- P-Bodies: Composition, Properties, and Functions
- (2018) Yang Luo et al. BIOCHEMISTRY
- Estimation of clinical trial success rates and related parameters
- (2018) Chi Heem Wong et al. BIOSTATISTICS
- Lipid–polymer hybrid nanocarrier-mediated cancer therapeutics: current status and future directions
- (2018) Neeraj K. Garg et al. DRUG DISCOVERY TODAY
- Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids
- (2018) Sam Chen et al. JOURNAL OF CONTROLLED RELEASE
- Structure of Lipid Nanoparticles Containing siRNA or mRNA by Dynamic Nuclear Polarization-Enhanced NMR Spectroscopy
- (2018) Jasmine Viger-Gravel et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Monitoring translation activity of mRNA-loaded nanoparticles in mice
- (2018) Sebastian Rosigkeit et al. MOLECULAR PHARMACEUTICS
- Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses
- (2018) Annette B. Vogel et al. MOLECULAR THERAPY
- A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates
- (2018) Staci Sabnis et al. MOLECULAR THERAPY
- A modular platform for targeted RNAi therapeutics
- (2018) Ranit Kedmi et al. Nature Nanotechnology
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
- (2018) David Adams et al. NEW ENGLAND JOURNAL OF MEDICINE
- Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles
- (2018) Marianna Yanez Arteta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Personalized vaccines for cancer immunotherapy
- (2018) Ugur Sahin et al. SCIENCE
- Use of nanoparticle concentration as a tool to understand the structural properties of colloids
- (2018) Lígia Nunes de Morais Ribeiro et al. Scientific Reports
- Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification
- (2018) Sriram Vaidyanathan et al. Molecular Therapy-Nucleic Acids
- Size-Controlled Lipid Nanoparticle Production Using Turbulent Mixing to Enhance Oral DNA Delivery
- (2018) Zhiyu He et al. Acta Biomaterialia
- Soft- and hard-lipid nanoparticles: a novel approach to lymphatic drug delivery
- (2018) Seung-Hyun Jeong et al. ARCHIVES OF PHARMACAL RESEARCH
- An RNA toolbox for cancer immunotherapy
- (2018) Fernando Pastor et al. NATURE REVIEWS DRUG DISCOVERY
- Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
- (2018) Norbert Pardi et al. Nature Communications
- Optimization of the Linker Length of Mannose-Cholesterol Conjugates for Enhanced mRNA Delivery to Dendritic Cells by Liposomes
- (2018) Fazhan Wang et al. Frontiers in Pharmacology
- New Vaccine Technologies to Combat Outbreak Situations
- (2018) Susanne Rauch et al. Frontiers in Immunology
- Dendrimer-Based Lipid Nanoparticles Deliver Therapeutic FAH mRNA to Normalize Liver Function and Extend Survival in a Mouse Model of Hepatorenal Tyrosinemia Type I
- (2018) Qiang Cheng et al. ADVANCED MATERIALS
- Phase I clinical trial of an intranodally administered mRNA based therapeutic vaccine against HIV-1 infection
- (2018) Lorna Leal et al. AIDS
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
- (2018) Cory D. Sago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes
- (2018) Nuphar Veiga et al. Nature Communications
- Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design
- (2017) Timothy Pepini et al. JOURNAL OF IMMUNOLOGY
- A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects
- (2017) Annett Ziegler et al. JOURNAL OF IMMUNOLOGY
- Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial
- (2017) Martin Alberer et al. LANCET
- Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques
- (2017) Frank Liang et al. MOLECULAR THERAPY
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Codon optimality, bias and usage in translation and mRNA decay
- (2017) Gavin Hanson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
- (2017) Yazan M. Abbas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics—An innate immune system standpoint
- (2017) Yasmin Granot et al. SEMINARS IN IMMUNOLOGY
- Type I Interferons Modulate CD8 + T Cell Immunity to mRNA Vaccines
- (2017) Ans De Beuckelaer et al. TRENDS IN MOLECULAR MEDICINE
- Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells
- (2017) Gustaf Lindgren et al. Frontiers in Immunology
- 50 years of oral lipid-based formulations: Provenance, progress and future perspectives
- (2016) Orlagh M. Feeney et al. ADVANCED DRUG DELIVERY REVIEWS
- PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
- (2016) Jung Soo Suk et al. ADVANCED DRUG DELIVERY REVIEWS
- Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
- (2016) Owen S. Fenton et al. ADVANCED MATERIALS
- Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
- (2016) Jason B. Miller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy
- (2016) Susan N. Thomas et al. Annual Review of Biomedical Engineering
- Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
- (2016) Kevin J. Kauffman et al. BIOMATERIALS
- Nanostructured lipid carrier mediates effective delivery of methotrexate to induce apoptosis of rheumatoid arthritis via NF-κB and FOXO1
- (2016) Neeraj K. Garg et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
- (2016) Sam Chen et al. JOURNAL OF CONTROLLED RELEASE
- Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses
- (2016) Ans De Beuckelaer et al. MOLECULAR THERAPY
- Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses
- (2016) Joseph A Katakowski et al. MOLECULAR THERAPY
- Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
- (2016) Matthias A. Oberli et al. NANO LETTERS
- The ligand (s) anchored lipobrid nanoconstruct mediated delivery of methotrexate: an effective approach in breast cancer therapeutics
- (2016) Neeraj K. Garg et al. Nanomedicine-Nanotechnology Biology and Medicine
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- The delivery of therapeutic oligonucleotides
- (2016) Rudolph L. Juliano NUCLEIC ACIDS RESEARCH
- Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination
- (2016) Hok Hei Tam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel lipid nanoparticle adjuvant significantly enhances B cell and T cell responses to sub-unit vaccine antigens
- (2016) Gokul Swaminathan et al. VACCINE
- Vaccine impact: Benefits for human health
- (2016) Mark Doherty et al. VACCINE
- Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia
- (2016) Joseph F. Nabhan et al. Scientific Reports
- Type-I Interferon Responses: From Friend to Foe in the Battle against Chronic Viral Infection
- (2016) Armstrong Murira et al. Frontiers in Immunology
- Cholesterol Modified Self-Assemblies and Their Application to Nanomedicine
- (2015) Francesca Ercole et al. BIOMACROMOLECULES
- A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA
- (2015) Christine Schuberth-Wagner et al. IMMUNITY
- A novel RNA-based adjuvant combines strong immunostimulatory capacities with a favorable safety profile
- (2015) Regina Heidenreich et al. INTERNATIONAL JOURNAL OF CANCER
- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
- (2015) Norbert Pardi et al. JOURNAL OF CONTROLLED RELEASE
- Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems
- (2015) Alex K. K. Leung et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin
- (2015) Michela Brazzoli et al. JOURNAL OF VIROLOGY
- Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
- (2015) Andreas Thess et al. MOLECULAR THERAPY
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity
- (2015) Natalie L. Trevaskis et al. NATURE REVIEWS DRUG DISCOVERY
- Toll-like receptor 8 senses degradation products of single-stranded RNA
- (2015) Hiromi Tanji et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Toll-like receptor 8 senses degradation products of single-stranded RNA
- (2015) Hiromi Tanji et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells
- (2015) Zhenzhen Liu et al. Frontiers in Physiology
- Towards Targeted Delivery Systems: Ligand Conjugation Strategies for mRNA Nanoparticle Tumor Vaccines
- (2015) Kyle K. L. Phua Journal of Immunology Research
- mRNA-based dendritic cell vaccines
- (2014) Daphné Benteyn et al. Expert Review of Vaccines
- Structure-based programming of lymph-node targeting in molecular vaccines
- (2014) Haipeng Liu et al. NATURE
- mRNA-based therapeutics — developing a new class of drugs
- (2014) Ugur Sahin et al. NATURE REVIEWS DRUG DISCOVERY
- The contribution of vaccination to global health: past, present and future
- (2014) B. Greenwood PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5
- (2014) G. E. Katibah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A critical analysis of codon optimization in human therapeutics
- (2014) Vincent P. Mauro et al. TRENDS IN MOLECULAR MEDICINE
- RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure
- (2014) Simon J Allison et al. Molecular Therapy-Nucleic Acids
- Dendritic Cell-Based Approaches in the Fight Against Diseases
- (2014) Rafael Freitas-Silva et al. Frontiers in Immunology
- Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
- (2013) Nicolas Bertrand et al. ADVANCED DRUG DELIVERY REVIEWS
- The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage
- (2013) Amr S. Abu Lila et al. JOURNAL OF CONTROLLED RELEASE
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
- (2013) Martin A Maier et al. MOLECULAR THERAPY
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Risk in Vaccine Research and Development Quantified
- (2013) Esther S. Pronker et al. PLoS One
- RNA pulsed dendritic cells: An approach for cancer immunotherapy
- (2013) Neeraj Kumar Garg et al. VACCINE
- mRNA
- (2013) Sandra Van Lint et al. Human Vaccines & Immunotherapeutics
- Liposomal drug delivery systems: From concept to clinical applications
- (2012) Theresa M. Allen et al. ADVANCED DRUG DELIVERY REVIEWS
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Transfection efficiency boost of cholesterol-containing lipoplexes
- (2012) Daniela Pozzi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The mannose receptor
- (2012) Luisa Martinez-Pomares JOURNAL OF LEUKOCYTE BIOLOGY
- Silent Substitutions Predictably Alter Translation Elongation Rates and Protein Folding Efficiencies
- (2012) Paige S. Spencer et al. JOURNAL OF MOLECULAR BIOLOGY
- Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core
- (2012) Alex K. K. Leung et al. Journal of Physical Chemistry C
- The origins of inoculation
- (2012) Arthur Boylston JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
- Good Codons, Bad Transcript: Large Reductions in Gene Expression and Fitness Arising from Synonymous Mutations in a Key Enzyme
- (2012) Deepa Agashe et al. MOLECULAR BIOLOGY AND EVOLUTION
- Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin
- (2012) Katalin Karikó et al. MOLECULAR THERAPY
- Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
- (2012) Charlotte Pollard et al. MOLECULAR THERAPY
- Effect of PEGylation on Biodistribution and Gene Silencing of siRNA/Lipid Nanoparticle Complexes
- (2012) Yanjie Bao et al. PHARMACEUTICAL RESEARCH
- Nonviral delivery of self-amplifying RNA vaccines
- (2012) A. J. Geall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Developing mRNA-vaccine technologies
- (2012) Thomas Schlake et al. RNA Biology
- RNA-based vaccines
- (2012) Jeffrey B. Ulmer et al. VACCINE
- Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA
- (2012) Nathan M Belliveau et al. Molecular Therapy-Nucleic Acids
- Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective
- (2011) S.M. Moghimi et al. Annual Review of Pharmacology and Toxicology
- The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
- (2011) Kai Xiao et al. BIOMATERIALS
- Tumor vaccination using messenger RNA: prospects of a future therapy
- (2011) Sebastian Kreiter et al. CURRENT OPINION IN IMMUNOLOGY
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles
- (2011) Marco P. Monopoli et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery
- (2011) Kathryn A Whitehead et al. MOLECULAR THERAPY
- Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
- (2011) Federico Perche et al. Nanomedicine-Nanotechnology Biology and Medicine
- Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
- (2011) Katalin Karikó et al. NUCLEIC ACIDS RESEARCH
- Robust Vaccine-Elicited Cellular Immune Responses in Breast Milk following Systemic Simian Immunodeficiency Virus DNA Prime and Live Virus Vector Boost Vaccination of Lactating Rhesus Monkeys
- (2010) A. B. Wilks et al. JOURNAL OF IMMUNOLOGY
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
- (2010) Bart R. Anderson et al. NUCLEIC ACIDS RESEARCH
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery
- (2009) Deepa A. Rao et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Coding-Sequence Determinants of Gene Expression in Escherichia coli
- (2009) G. Kudla et al. SCIENCE
- Nanoparticles target distinct dendritic cell populations according to their size
- (2008) Vania Manolova et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA
- (2008) Benjamin Weide et al. JOURNAL OF IMMUNOTHERAPY
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- Drug delivery: Stealth particles give mucus the slip
- (2008) Yen Cu et al. NATURE MATERIALS
- Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner
- (2008) S. R. Nallagatla et al. RNA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started