Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design

Recent innovations in mRNA vaccines

(2016) Jeffrey B Ulmer et al.   CURRENT OPINION IN IMMUNOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

(2014) A. Forsbach et al.   JOURNAL OF IMMUNOLOGY

Master sensors of pathogenic RNA – RIG-I like receptors

(2013) Martin Schlee   IMMUNOBIOLOGY

RNA: The new revolution in nucleic acid vaccines

(2013) Andrew J. Geall et al.   SEMINARS IN IMMUNOLOGY

Interferon-induced ISG15 pathway: an ongoing virus–host battle

(2013) Chen Zhao et al.   TRENDS IN MICROBIOLOGY

Engineered alphavirus replicon vaccines based on known attenuated viral mutants show limited effects on immunogenicity

(2013) Giulietta Maruggi et al.   VIROLOGY

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

TLR8: the forgotten relative revindicated

(2012) Jorge L Cervantes et al.   Cellular & Molecular Immunology

Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines

(2012) Charlotte Pollard et al.   MOLECULAR THERAPY

Nonviral delivery of self-amplifying RNA vaccines

(2012) A. J. Geall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of delivery systems on siRNA immune activation and RNA interference

(2011) Alexandra Forsbach et al.   IMMUNOLOGY LETTERS

A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding

(2011) Carlo Iavarone et al.   JOURNAL OF IMMUNOLOGY

Viperin, a key player in the antiviral response

(2011) Sandy Mattijssen et al.   MICROBES AND INFECTION

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

(2011) K. A. Swanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT1 and pathogens, not a friendly relationship

(2010) Imen Najjar et al.   BIOCHIMIE

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Messenger RNA-based Vaccines With Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity

(2010) Mariola Fotin-Mleczek et al.   JOURNAL OF IMMUNOTHERAPY

Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein

(2010) Catherine C. Cruz et al.   VIROLOGY

Alternating 2′-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist

(2009) Svetlana Hamm et al.   IMMUNOBIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Forward genetic analysis of TLR-signaling pathways: An evaluation☆

(2008) K HOEBE et al.   ADVANCED DRUG DELIVERY REVIEWS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH