From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity
Authors
Keywords
-
Journal
NATURE REVIEWS DRUG DISCOVERY
Volume 14, Issue 11, Pages 781-803
Publisher
Springer Nature
Online
2015-10-16
DOI
10.1038/nrd4608
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations
- (2015) Pavan Puligujja et al. BIOMATERIALS
- Biomimetic reassembled chylomicrons as novel association model for the prediction of lymphatic transportation of highly lipophilic drugs via the oral route
- (2015) Yi Lu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses
- (2015) Qin Zeng et al. JOURNAL OF CONTROLLED RELEASE
- A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
- (2015) Aleksanteri Aspelund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Methotrexate-Conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumor-Burdened Lymph Nodes after Intravenous and Subcutaneous Administration in Rats
- (2015) Lisa M. Kaminskas et al. MOLECULAR PHARMACEUTICS
- Structural and functional features of central nervous system lymphatic vessels
- (2015) Antoine Louveau et al. NATURE
- Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery
- (2015) Susan N Thomas et al. Current Opinion in Chemical Engineering
- Harnessing Biomaterials to Engineer the Lymph Node Microenvironment for Immunity or Tolerance
- (2014) James I. Andorko et al. AAPS Journal
- Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood
- (2014) Jennifer P. Freeling et al. AIDS
- Obesity increases inflammation and impairs lymphatic function in a mouse model of lymphedema
- (2014) Ira L. Savetsky et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Lipid–calcium phosphate nanoparticles for delivery to the lymphatic system and SPECT/CT imaging of lymph node metastases
- (2014) Yu-Cheng Tseng et al. BIOMATERIALS
- Development of HIV Reservoir Targeted Long Acting Nanoformulated Antiretroviral Therapies
- (2014) Benson Edagwa et al. CURRENT MEDICINAL CHEMISTRY
- Lipid nanoparticles for oral delivery of raloxifene: Optimization, stability, in vivo evaluation and uptake mechanism
- (2014) Punna Rao Ravi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- VEGF-C–dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease
- (2014) Silvia D’Alessio et al. JOURNAL OF CLINICAL INVESTIGATION
- New developments in clinical aspects of lymphatic disease
- (2014) Peter S. Mortimer et al. JOURNAL OF CLINICAL INVESTIGATION
- Emerging roles of lymphatic endothelium in regulating adaptive immunity
- (2014) Catherine M. Card et al. JOURNAL OF CLINICAL INVESTIGATION
- Lymphatic transport of high-density lipoproteins and chylomicrons
- (2014) Gwendalyn J. Randolph et al. JOURNAL OF CLINICAL INVESTIGATION
- Novel self assembling nanoparticles for the oral administration of fondaparinux: Synthesis, characterization and in vivo evaluation
- (2014) Bettina Ralay-Ranaivo et al. JOURNAL OF CONTROLLED RELEASE
- Nano-chemotherapeutics: Maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers
- (2014) Gemma M. Ryan et al. JOURNAL OF CONTROLLED RELEASE
- Targeted delivery of a model immunomodulator to the lymphatic system: Comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies
- (2014) Sifei Han et al. JOURNAL OF CONTROLLED RELEASE
- Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine
- (2014) Matthew C. Woodruff et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structure-based programming of lymph-node targeting in molecular vaccines
- (2014) Haipeng Liu et al. NATURE
- The role of ligand efficiency metrics in drug discovery
- (2014) Andrew L. Hopkins et al. NATURE REVIEWS DRUG DISCOVERY
- Exploring the Impact of Drug Properties on the Extent of Intestinal Lymphatic Transport - In Vitro and In Vivo Studies
- (2014) Emma Lawless et al. PHARMACEUTICAL RESEARCH
- Chronic High-Fat Diet Impairs Collecting Lymphatic Vessel Function in Mice
- (2014) Katrin S. Blum et al. PLoS One
- Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
- (2014) Courtney V. Fletcher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance
- (2014) Roberto A. Maldonado et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence
- (2014) J. P. Freeling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lymphatic-targeted cationic liposomes: A robust vaccine adjuvant for promoting long-term immunological memory
- (2014) Ce Wang et al. VACCINE
- Single, escalating dose pharmacokinetics, safety and food effects of a new oral androgen dimethandrolone undecanoate in man: a prototype oral male hormonal contraceptive
- (2014) P. Surampudi et al. Andrology
- Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes
- (2014) L. Jeanbart et al. Cancer Immunology Research
- Oral delivery of proteins by biodegradable nanoparticles
- (2013) Sasha H. Bakhru et al. ADVANCED DRUG DELIVERY REVIEWS
- Lymphatic vessels: new targets for the treatment of inflammatory diseases
- (2013) Lothar C. Dieterich et al. ANGIOGENESIS
- The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes
- (2013) Changhui Fu et al. BIOMATERIALS
- Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response
- (2013) Susan N. Thomas et al. BIOMATERIALS
- Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL
- (2013) Hwee Ying Lim et al. Cell Metabolism
- Apelin Inhibits Diet-Induced Obesity by Enhancing Lymphatic and Blood Vessel Integrity
- (2013) M. Sawane et al. DIABETES
- Bile salts enhance the intestinal absorption of lipophilic drug loaded lipid nanocarriers: Mechanism and effect in rats
- (2013) Zhiwen Zhang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice
- (2013) Catherine Martel et al. JOURNAL OF CLINICAL INVESTIGATION
- Brain-wide pathway for waste clearance captured by contrast-enhanced MRI
- (2013) Jeffrey J. Iliff et al. JOURNAL OF CLINICAL INVESTIGATION
- PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin
- (2013) Gemma M. Ryan et al. JOURNAL OF CONTROLLED RELEASE
- Polymeric micelles for enhanced lymphatic drug delivery to treat metastatic tumors
- (2013) Lei Qin et al. JOURNAL OF CONTROLLED RELEASE
- PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases
- (2013) Lisa M. Kaminskas et al. JOURNAL OF CONTROLLED RELEASE
- Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis
- (2013) Zhenghong Xu et al. JOURNAL OF CONTROLLED RELEASE
- Expansion of the lymphatic vasculature in cancer and inflammation: New opportunities for in vivo imaging and drug delivery
- (2013) Steven T. Proulx et al. JOURNAL OF CONTROLLED RELEASE
- Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain
- (2013) J. J. Iliff et al. JOURNAL OF NEUROSCIENCE
- The Impact of Lymphatic Transport on the Systemic Disposition of Lipophilic Drugs
- (2013) Suzanne M. Caliph et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer
- (2013) Lijun Yang et al. Journal of Translational Medicine
- Pulmonary Administration of PEGylated Polylysine Dendrimers: Absorption from the Lung versus Retention within the Lung Is Highly Size-Dependent
- (2013) Gemma M. Ryan et al. MOLECULAR PHARMACEUTICS
- The Lymphatic System Plays a Major Role in the Intravenous and Subcutaneous Pharmacokinetics of Trastuzumab in Rats
- (2013) Annette M. Dahlberg et al. MOLECULAR PHARMACEUTICS
- Engineering synthetic vaccines using cues from natural immunity
- (2013) Darrell J. Irvine et al. NATURE MATERIALS
- A Mouse Model to Evaluate the Impact of Species, Sex, and Lipid Load on Lymphatic Drug Transport
- (2013) Natalie L. Trevaskis et al. PHARMACEUTICAL RESEARCH
- Demonstration of ATP-Dependent, Transcellular Transport of Lipid Across the Lymphatic Endothelium Using an In Vitro Model of the Lacteal
- (2013) Alana L. Reed et al. PHARMACEUTICAL RESEARCH
- Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice
- (2013) Iraklis C. Kourtis et al. PLoS One
- Local Targeted Therapy of Liver Metastasis from Colon Cancer by Galactosylated Liposome Encapsulated with Doxorubicin
- (2013) Chen Zhao et al. PLoS One
- Obesity Impairs Lymphatic Fluid Transport and Dendritic Cell Migration to Lymph Nodes
- (2013) Evan S. Weitman et al. PLoS One
- Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption
- (2013) S. Attili-Qadri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unique insights into the intestinal absorption, transit, and subsequent biodistribution of polymer-derived microspheres
- (2013) Joshua J. Reineke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose
- (2013) A. de Titta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sleep Facilitates Clearance of Metabolites from the Brain: Glymphatic Function in Aging and Neurodegenerative Diseases
- (2013) Andrew R. Mendelsohn et al. REJUVENATION RESEARCH
- Sleep Drives Metabolite Clearance from the Adult Brain
- (2013) L. Xie et al. SCIENCE
- Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery
- (2013) E. M. Pridgen et al. Science Translational Medicine
- Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain
- (2013) Vinita Rangroo Thrane et al. Scientific Reports
- Mechanism of oral tolerance induction to therapeutic proteins
- (2012) Xiaomei Wang et al. ADVANCED DRUG DELIVERY REVIEWS
- Nanoparticles for oral delivery: Targeted nanoparticles with peptidic ligands for oral protein delivery
- (2012) Yeonhee Yun et al. ADVANCED DRUG DELIVERY REVIEWS
- Efficacy of Topical Blockade of Interleukin-1 in Experimental Dry Eye Disease
- (2012) Andre Okanobo et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles
- (2012) Rong Liu et al. BIOMATERIALS
- Lymphatic trafficking kinetics and near-infrared imaging using star polymer architectures with controlled anionic character
- (2012) Taryn R. Bagby et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats
- (2012) Jordi Ribera et al. GUT
- Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?
- (2012) N Arngrim et al. INTERNATIONAL JOURNAL OF OBESITY
- Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis
- (2012) Md. Rafi et al. JOURNAL OF CONTROLLED RELEASE
- A self-assembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor
- (2012) Zhiwen Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Nanoparticle Migration and Delivery of Paclitaxel to Regional Lymph Nodes in a Large Animal Model
- (2012) Onkar V. Khullar et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- Feasibility of Eradication of Breast Cancer Cells Remaining in Postlumpectomy Cavity and Draining Lymph Nodes following Intracavitary Injection of Radioactive Immunoliposomes
- (2012) Shihong Li et al. MOLECULAR PHARMACEUTICS
- Oral tolerance to food protein
- (2012) O Pabst et al. Mucosal Immunology
- Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective
- (2012) A. Christy Hunter et al. Nanomedicine-Nanotechnology Biology and Medicine
- Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
- (2012) Daniel R Getts et al. NATURE BIOTECHNOLOGY
- Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes
- (2012) Ashley L. St. John et al. NATURE MATERIALS
- Large intestine–targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection
- (2012) Qing Zhu et al. NATURE MEDICINE
- Rapid Lymph Accumulation of Polystyrene Nanoparticles Following Pulmonary Administration
- (2012) Abdul Khader Mohammad et al. PHARMACEUTICAL RESEARCH
- Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer
- (2012) Helge Wiig et al. PHYSIOLOGICAL REVIEWS
- Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
- (2012) J. J. Moon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineering Approaches to Immunotherapy
- (2012) M. A. Swartz et al. Science Translational Medicine
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Attenuation of transplant arteriosclerosis by oral feeding of major histocompatibility complex encoding chitosan-DNA nanoparticles
- (2012) Katja Goldmann et al. TRANSPLANT IMMUNOLOGY
- Nanoparticle size influences the magnitude and quality of mucosal immune responses after intranasal immunization
- (2012) Armando Stano et al. VACCINE
- Lymphatic vessels in health and disease
- (2012) Cristina T. Kesler et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Mucosal Immune System and M Cell-targeting Strategies for Oral Mucosal Vaccination
- (2012) Sae-Hae Kim et al. Immune Network
- The role of the lymphatic system in vaccine trafficking and immune response
- (2011) Ivy Pal et al. ADVANCED DRUG DELIVERY REVIEWS
- Advances in lymphatic imaging and drug delivery
- (2011) Satish K. Nune et al. ADVANCED DRUG DELIVERY REVIEWS
- Intestinal lymphatic transport for drug delivery
- (2011) Jaime A. Yáñez et al. ADVANCED DRUG DELIVERY REVIEWS
- Gut-associated lymphoid tissues for the development of oral vaccines
- (2011) Jun Kunisawa et al. ADVANCED DRUG DELIVERY REVIEWS
- Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport
- (2011) Norman E. Miller et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Nanoparticle Delivery of Mycophenolic Acid Upregulates PD-L1 on Dendritic Cells to Prolong Murine Allograft Survival
- (2011) A. C. Shirali et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
- (2011) Yun Jin et al. BIOMATERIALS
- An important role of lymphatic vessel activation in limiting acute inflammation
- (2011) R. Huggenberger et al. BLOOD
- Role of the lymphatic system in the pathogenesis of Crohnʼs disease
- (2011) Pierre-Yves von der Weid et al. CURRENT OPINION IN GASTROENTEROLOGY
- Magnetic functionalised carbon nanotubes as drug vehicles for cancer lymph node metastasis treatment
- (2011) Feng Yang et al. EUROPEAN JOURNAL OF CANCER
- Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: Linear correlation with oral bioavailabilities in rats
- (2011) Minghui Sun et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Oral tolerance
- (2011) Howard L. Weiner et al. IMMUNOLOGICAL REVIEWS
- A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary
- (2011) Rym Skanji et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival
- (2011) Karen Y. Dane et al. JOURNAL OF CONTROLLED RELEASE
- LyP-1-conjugated PEGylated liposomes: A carrier system for targeted therapy of lymphatic metastatic tumor
- (2011) Zhiqiang Yan et al. JOURNAL OF CONTROLLED RELEASE
- Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma
- (2011) Satoru Shinriki et al. JOURNAL OF PATHOLOGY
- Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration
- (2011) Asolina Braun et al. NATURE IMMUNOLOGY
- Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
- (2011) James J. Moon et al. NATURE MATERIALS
- The lymphatic vasculature in disease
- (2011) Kari Alitalo NATURE MEDICINE
- Induced Immune Tolerance for Kidney Transplantation
- (2011) John D. Scandling et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interaction of tumor cells and lymphatic vessels in cancer progression
- (2011) A Alitalo et al. ONCOGENE
- In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles
- (2011) C. M. Jewell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination
- (2011) C. Nembrini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired lymphatic contraction associated with immunosuppression
- (2011) S. Liao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Visualização da Rede Linfática Pulmonar Profunda usando Radioliposomas
- (2011) M.F. Botelho et al. Revista Portuguesa de Pneumologia
- Exploiting mucosal surfaces for the development of mucosal vaccines
- (2011) Els N. Meeusen VACCINE
- Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis
- (2011) Marie Ballester et al. VACCINE
- Bronchus-Associated Lymphoid Tissue
- (2010) Reinhard Pabst et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Gut lymph and lymphatics: a source of factors leading to organ injury and dysfunction
- (2010) Edwin A. Deitch Annals of the New York Academy of Sciences
- Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions
- (2010) Triantafyllos Stylianopoulos et al. BIOPHYSICAL JOURNAL
- Microvascular fluid exchange and the revised Starling principle
- (2010) J. Rodney Levick et al. CARDIOVASCULAR RESEARCH
- Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages
- (2010) Laeticia Lichtenstein et al. Cell Metabolism
- Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium
- (2010) Dimana O. Miteva et al. CIRCULATION RESEARCH
- Current views on the function of the lymphatic vasculature in health and disease
- (2010) Y. Wang et al. GENES & DEVELOPMENT
- Immunology of gut mucosal vaccines
- (2010) Marcela F. Pasetti et al. IMMUNOLOGICAL REVIEWS
- Update on Macrophage Clearance of Inhaled Micro- and Nanoparticles
- (2010) Marianne Geiser Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Ebola haemorrhagic fever
- (2010) Heinz Feldmann et al. LANCET
- Targeted Drug Delivery to Lymphocytes: A Route to Site-Specific Immunomodulation?
- (2010) Natalie L. Trevaskis et al. MOLECULAR PHARMACEUTICS
- Multiple facets of intestinal permeability and epithelial handling of dietary antigens
- (2010) S Ménard et al. Mucosal Immunology
- Rapid translocation of nanoparticles from the lung airspaces to the body
- (2010) Hak Soo Choi et al. NATURE BIOTECHNOLOGY
- The Mechanism of Lymphatic Access of Two Cholesteryl Ester Transfer Protein Inhibitors (CP524,515 and CP532,623) and Evaluation of Their Impact on Lymph Lipoprotein Profiles
- (2010) Natalie L. Trevaskis et al. PHARMACEUTICAL RESEARCH
- Microneedle-Based Intradermal Delivery Enables Rapid Lymphatic Uptake and Distribution of Protein Drugs
- (2010) Alfred J. Harvey et al. PHARMACEUTICAL RESEARCH
- Lymphatic lipid transport: sewer or subway?
- (2010) J. Brandon Dixon TRENDS IN ENDOCRINOLOGY AND METABOLISM
- PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration
- (2010) Armando Stano et al. VACCINE
- Nanotechnology-based systems for the treatment and prevention of HIV/AIDS
- (2009) José das Neves et al. ADVANCED DRUG DELIVERY REVIEWS
- Hypercholesterolemic Mice Exhibit Lymphatic Vessel Dysfunction and Degeneration
- (2009) Hwee Ying Lim et al. AMERICAN JOURNAL OF PATHOLOGY
- A tissue-engineered model of the intestinal lacteal for evaluating lipid transport by lymphatics
- (2009) J. Brandon Dixon et al. BIOTECHNOLOGY AND BIOENGINEERING
- Intralymphatic immunotherapy
- (2009) Gabriela Senti et al. Current Opinion in Allergy and Clinical Immunology
- Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination
- (2009) Virginie Fievez et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Aerosol Delivery of Liposomal Formulated Paclitaxel and Vitamin E Analog Reduces Murine Mammary Tumor Burden and Metastases
- (2009) Paul Latimer et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors
- (2009) Guopei Luo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats
- (2009) Lisa M. Kaminskas et al. JOURNAL OF CONTROLLED RELEASE
- Drug delivery systems in HIV pharmacotherapy: What has been done and the challenges standing ahead
- (2009) Alejandro Sosnik et al. JOURNAL OF CONTROLLED RELEASE
- Roles of dextrans on improving lymphatic drainage for liposomal drug delivery system
- (2009) Linglin Feng et al. JOURNAL OF DRUG TARGETING
- Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
- (2009) Olga Schulz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Intralobular Pulmonary Lymphatic Distribution in Normal Human Lung Using D2-40 Antipodoplanin Immunostaining
- (2009) Marianne Kambouchner et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Antigen-Specific Suppression of Inflammatory Arthritis Using Liposomes
- (2009) C. Capini et al. JOURNAL OF IMMUNOLOGY
- Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery
- (2009) Deepa A. Rao et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Lymphatic Transport of Methylnortestosterone Undecanoate (MU) and the Bioavailability of Methylnortestosterone Are Highly Sensitive to the Mass of Coadministered Lipid after Oral Administration of MU
- (2009) K. L. White et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The role of molecular physicochemical properties and apolipoproteins in association of drugs with triglyceride-rich lipoproteins: in-silico prediction of uptake by chylomicrons
- (2009) Pavel Gershkovich et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism
- (2009) Agnes Machnik et al. NATURE MEDICINE
- Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism
- (2009) Natalie L. Trevaskis et al. PHARMACEUTICAL RESEARCH
- Chylomicrons Promote Intestinal Absorption and Systemic Dissemination of Dietary Antigen (Ovalbumin) in Mice
- (2009) Yuehui Wang et al. PLoS One
- Lymphangiogenesis and Lymphatic Remodeling Induced by Filarial Parasites: Implications for Pathogenesis
- (2009) Sasisekhar Bennuru et al. PLoS Pathogens
- The Link between Lymphatic Function and Adipose Biology
- (2008) Natasha L. Harvey Annals of the New York Academy of Sciences
- Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints
- (2008) K Polzer et al. ANNALS OF THE RHEUMATIC DISEASES
- Hyaluronic acid–polyethyleneimine conjugate for target specific intracellular delivery of siRNA
- (2008) Ge Jiang et al. BIOPOLYMERS
- Association between persistent lymphatic infection by hepatitis C virus after antiviral treatment and mixed cryoglobulinemia
- (2008) C. Giannini et al. BLOOD
- Synthetic CD4+ T Cell-Targeted Antigen-Presenting Cells Elicit Protective Antitumor Responses
- (2008) S. Caserta et al. CANCER RESEARCH
- Mitochondrial/Cell-Surface Protein p32/gC1qR as a Molecular Target in Tumor Cells and Tumor Stroma
- (2008) V. Fogal et al. CANCER RESEARCH
- Nanoparticles target distinct dendritic cell populations according to their size
- (2008) Vania Manolova et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Biodegradable polymeric nanocarriers for pulmonary drug delivery
- (2008) Erik Rytting et al. Expert Opinion on Drug Delivery
- Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice
- (2008) Jean-François Nicolas et al. Expert Review of Vaccines
- Ovalbumin-Protein σ1 M-Cell Targeting Facilitates Oral Tolerance With Reduction of Antigen-Specific CD4+ T Cells
- (2008) Hideaki Suzuki et al. GASTROENTEROLOGY
- Oral tolerance, food allergy, and immunotherapy: Implications for future treatment
- (2008) A. Wesley Burks et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Accumulation of Fingolimod (FTY720) in Lymphoid Tissues Contributes to Prolonged Efficacy
- (2008) S.-C. Sensken et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Intralymphatic Chemotherapy Using a Hyaluronan–Cisplatin Conjugate
- (2008) Shuang Cai et al. JOURNAL OF SURGICAL RESEARCH
- Targeting of albumin-embedded paclitaxel nanoparticles to tumors
- (2008) Priya Prakash Karmali et al. Nanomedicine-Nanotechnology Biology and Medicine
- Ultrasound Imaging of the Thoracic Duct
- (2008) Marcus Seeger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Visceral Fat Accumulation Induced by a High-fat Diet Causes the Atrophy of Mesenteric Lymph Nodes in Obese Mice
- (2008) C.S. Kim et al. Obesity
- Intralymphatic allergen administration renders specific immunotherapy faster and safer: A randomized controlled trial
- (2008) G. Senti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intradermal vaccine delivery: Will new delivery systems transform vaccine administration?
- (2008) Paul Henri Lambert et al. VACCINE
- Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update
- (2007) Natalie L. Trevaskis et al. ADVANCED DRUG DELIVERY REVIEWS
- The oral absorption of phospholipid prodrugs: In vivo and in vitro mechanistic investigation of trafficking of a lecithin-valproic acid conjugate following oral administration
- (2007) Arik Dahan et al. JOURNAL OF CONTROLLED RELEASE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started