Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

Small Interfering RNAs Induce Macrophage Migration Inhibitory Factor Production and Proliferation in Breast Cancer Cells via a Double-Stranded RNA-Dependent Protein Kinase-Dependent Mechanism

(2014) M. E. Armstrong et al.   JOURNAL OF IMMUNOLOGY

Modifications Incorporated in CpG Motifs of Oligodeoxynucleotides Lead to Antagonist Activity of Toll-like Receptors 7 and 9

(2009) Dong Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dynamic refolding of IFN-γ mRNA enables it to function as PKR activator and translation template

(2009) Smadar Cohen-Chalamish et al.   Nature Chemical Biology

Activity of siRNAs with 2-Thio-2′-O-Methyluridine Modification in Mammalian Cells

(2009) Thazha P. Prakash et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Influenza B Virus Ribonucleoprotein Is a Potent Activator of the Antiviral Kinase PKR

(2009) Bianca Dauber et al.   PLoS Pathogens

Astrocytes are very sensitive to develop innate immune responses to lipid-carried short interfering RNA

(2008) Roser Gorina et al.   GLIA

Oligodeoxyribonucleotide-Based Antagonists for Toll-Like Receptors 7 and 9

(2008) Daqing Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

(2008) Katalin Karikó et al.   MOLECULAR THERAPY

Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner

(2008) S. R. Nallagatla et al.   RNA