The Interplay of HIV and Autophagy in Early Infection

A conserved ATG2‐GABARAP family interaction is critical for phagophore formation

(2020) Mihaela Bozic et al.   EMBO REPORTS

Permanent control of HIV-1 pathogenesis in exceptional elite controllers: a model of spontaneous cure

(2020) Concepcion Casado et al.   Scientific Reports

Life, death, and autophagy in cancer: NF-κB turns up everywhere

(2020) Daniela Verzella et al.   Cell Death & Disease

Modulation of mTORC1 Signaling Pathway by HIV-1

(2020) Burkitkan Akbay et al.   Cells

Functional Characterisation of the Autophagy ATG12~5/16 Complex in Dictyostelium discoideum

(2020) Malte Karow et al.   Cells

Endoplasmic Reticulum Membrane and Contact Site Dynamics in Autophagy Regulation and Stress Response

(2020) Etienne Morel   Frontiers in Cell and Developmental Biology

Trehalose Inhibits Human Immunodeficiency Virus type-1 Infection in Primary Human Macrophages and CD4+ T lymphocytes through Two Distinct Mechanisms

(2020) Pratima Rawat et al.   JOURNAL OF VIROLOGY

Haemopoietic cell transplantation in patients living with HIV

(2020) Richard F Ambinder et al.   Lancet HIV

Resistance Profile of Human Immunodeficiency Virus 1 (HIV-1) Quasispecies in Patients Under Treatment Failure Using Single Molecule, Real-Time (SMRT) Sequencing

(2020) Daniela C. Monaco et al.   AIDS

HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death

(2020) Coralie F Daussy et al.   Autophagy

Endoplasmic reticulum stress and autophagy in HIV-1-associated neurocognitive disorders

(2020) Xue Chen et al.   JOURNAL OF NEUROVIROLOGY

Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

(2020) Kazuaki Matoba et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation

(2020) Justyna Sawa-Makarska et al.   SCIENCE

A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α

(2020) Bhaskar Saha et al.   PLoS Pathogens

Sorting nexin 5 mediates virus-induced autophagy and immunity

(2020) Xiaonan Dong et al.   NATURE

Editing of the TRIM5 Gene Decreases the Permissiveness of Human T Lymphocytic Cells to HIV-1

(2020) Kevin Désaulniers et al.   Viruses-Basel

Author Correction: Clearance of HIV infection by selective elimination of host cells capable of producing HIV

(2020) Min Li et al.   Nature Communications

Viral reservoirs in elite controllers of HIV-1 infection: Implications for HIV cure strategies

(2020) Bezawit A. Woldemeskel et al.   EBioMedicine

Atg2 mediates direct lipid transfer between membranes for autophagosome formation

(2019) Takuo Osawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

(2019) Ravindra K. Gupta et al.   NATURE

Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells

(2019) Dong Sun Oh et al.   Autophagy

HIV long-term non-progressors elite controllers: an interplay between host, immune and viral factors

(2019) Cecilio López-Galíndez   Future Virology

The Dual Role of HIV-1 gp120 V3 Loop-Induced Autophagy in the Survival and Apoptosis of the Primary Rat Hippocampal Neurons

(2019) Sisi Liu et al.   NEUROCHEMICAL RESEARCH

Dual Role of Autophagy in Diseases of the Central Nervous System

(2019) Tamara Bar-Yosef et al.   Frontiers in Cellular Neuroscience

Two distinct mechanisms target the autophagy-related E3 complex to the pre-autophagosomal structure

(2019) Kumi Harada et al.   eLife

Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage

(2019) Borrajo et al.   Medicina-Lithuania

The autophagy protein ATG9A promotes HIV-1 infectivity

(2019) Elodie Mailler et al.   Retrovirology

Molecular Mechanism of HIV-1 Entry

(2019) Bing Chen   TRENDS IN MICROBIOLOGY

HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic

(2019) Romina Cabrera-Rodríguez et al.   Scientific Reports

ATG2 regulation of phagophore expansion at mitochondria-associated ER membranes

(2019) Zhenyuan Tang et al.   Autophagy

HIV‐1 Vpr inhibits autophagy during the early steps of infection of CD4 T cells

(2019) Jamal Alfaisal et al.   BIOLOGY OF THE CELL

Phylogenies in ART: HIV reservoirs, HIV latency and drug resistance

(2019) Alessandra Bandera et al.   CURRENT OPINION IN PHARMACOLOGY

Elite controllers and lessons learned for HIV-1 cure

(2019) Cecilio Lopez-Galindez et al.   Current Opinion in Virology

The potential of engineered antibodies for HIV-1 therapy and cure

(2019) Marloes Grobben et al.   Current Opinion in Virology

HIV-1 Nef Targets HDAC6 to Assure Viral Production and Virus Infection

(2019) Sara Marrero-Hernández et al.   Frontiers in Microbiology

New Challenges of HIV-1 Infection: How HIV-1 Attacks and Resides in the Central Nervous System

(2019) Victoria Rojas-Celis et al.   Cells

Combating the HIV reservoirs

(2018) Guido van Marle et al.   Biotechnology & Genetic Engineering Reviews

The Biology of CRISPR-Cas: Backward and Forward

(2018) Frank Hille et al.   CELL

HIV-1 entry inhibitors: A review of experimental and computational studies

(2018) Tahere Mostashari Rad et al.   CHEMISTRY & BIODIVERSITY

Atg9 establishes Atg2-dependent contact sites between the endoplasmic reticulum and phagophores

(2018) Rubén Gómez-Sánchez et al.   JOURNAL OF CELL BIOLOGY

Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1

(2018) Ayub Ali et al.   JOURNAL OF INFECTIOUS DISEASES

Autophagy during Early Virus–Host Cell Interactions

(2018) Christophe Viret et al.   JOURNAL OF MOLECULAR BIOLOGY

Autophagy and MHC-restricted antigen presentation

(2018) Jan Valečka et al.   MOLECULAR IMMUNOLOGY

Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection

(2018) Donn J. Colby et al.   NATURE MEDICINE

Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1

(2018) Caroline Dufour et al.   PLoS One

Viral Characteristics Associated with the Clinical Nonprogressor Phenotype Are Inherited by Viruses from a Cluster of HIV-1 Elite Controllers

(2018) Concepción Casado et al.   mBio

Molecular Signatures of HIV-1 Envelope Associated with HIV-Associated Neurocognitive Disorders

(2018) Teresa H. Evering   Current HIV/AIDS Reports

HIV Persistence in Adipose Tissue Reservoirs

(2018) Jacob Couturier et al.   Current HIV/AIDS Reports

A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction

(2018) Maro Iliopoulou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of coreceptor recognition by HIV-1 envelope spike

(2018) Md Munan Shaik et al.   NATURE

HIV control: Is getting there the same as staying there?

(2018) Philip Goulder et al.   PLoS Pathogens

CCR5 structural plasticity shapes HIV-1 phenotypic properties

(2018) Philippe Colin et al.   PLoS Pathogens

Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1

(2018) Marta Colomer-Lluch et al.   Frontiers in Immunology

Antibodies and Antibody Derivatives: New Partners in HIV Eradication Strategies

(2018) Jorge Carrillo et al.   Frontiers in Immunology

The HIV-1 envelope glycoprotein structure: nailing down a moving target

(2017) Andrew B Ward et al.   IMMUNOLOGICAL REVIEWS

HIV-1 strains belonging to large phylogenetic clusters show accelerated escape from integrase inhibitors in cell culture compared with viral isolates from singleton/small clusters

(2017) Bluma G. Brenner et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins

(2017) Chetan Sood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of autophagy in HIV infection and pathogenesis

(2017) R. Nardacci et al.   JOURNAL OF INTERNAL MEDICINE

Imaging HIV-1 Genomic DNA from Entry through Productive Infection

(2017) Ryan D. Stultz et al.   JOURNAL OF VIROLOGY

CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo

(2017) Lei Xu et al.   MOLECULAR THERAPY

Re-evaluating evolution in the HIV reservoir

(2017) Daniel I. S. Rosenbloom et al.   NATURE

PLA2G16 represents a switch between entry and clearance of Picornaviridae

(2017) Jacqueline Staring et al.   NATURE

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Canonical and Non-Canonical Autophagy in HIV-1 Replication Cycle

(2017) Olivier Leymarie et al.   Viruses-Basel

Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors

(2017) Isabelle Malet et al.   mBio

Is trehalose an autophagic inducer? Unraveling the roles of non-reducing disaccharides on autophagic flux and alpha-synuclein aggregation

(2017) Ye-Seul Yoon et al.   Cell Death & Disease

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study

(2017) Timothy J. Henrich et al.   PLOS MEDICINE

Mechanisms of HIV-1 Control

(2017) Mary Soliman et al.   Current HIV/AIDS Reports

Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era

(2017) Daryl Anne Victoria Weatherley et al.   Frontiers in Immunology

The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation

(2017) Ahmed M. Fahmy et al.   Scientific Reports

Autophagy plays an essential role in cigarette smoke-induced expression of MUC5AC in airway epithelium

(2016) Jie-Sen Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Dissecting How CD4 T Cells Are Lost During HIV Infection

(2016) Gilad Doitsh et al.   Cell Host & Microbe

Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study

(2016) R Kaminski et al.   GENE THERAPY

Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus

(2016) Ming-Ming Hu et al.   IMMUNITY

Autophagy and proteasome interconnect to coordinate cross-presentation through MHC class I pathway in B cells

(2016) Vijayendra Dasari et al.   IMMUNOLOGY AND CELL BIOLOGY

Hematopoietic stem cell transplantation for HIV cure

(2016) Daniel R. Kuritzkes   JOURNAL OF CLINICAL INVESTIGATION

HIV-1 Env Glycoprotein Phenotype along with Immune Activation Determines CD4 T Cell Loss in HIV Patients

(2016) Anjali Joshi et al.   JOURNAL OF IMMUNOLOGY

Long-Term Spontaneous Control of HIV-1 Is Related to Low Frequency of Infected Cells and Inefficient Viral Reactivation

(2016) Nicolas Noel et al.   JOURNAL OF VIROLOGY

Toll-Like Receptor 2 Ligation Enhances HIV-1 Replication in Activated CCR6 + CD4 + T Cells by Increasing Virus Entry and Establishing a More Permissive Environment to Infection

(2016) Jean-François Bolduc et al.   JOURNAL OF VIROLOGY

Role of Autophagy in HIV Pathogenesis and Drug Abuse

(2016) Lu Cao et al.   MOLECULAR NEUROBIOLOGY

CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape

(2016) Gang Wang et al.   MOLECULAR THERAPY

Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets

(2016) Carla M. S. Ribeiro et al.   NATURE

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

(2016) Johannes F. Scheid et al.   NATURE

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

(2016) Katharine J. Bar et al.   NEW ENGLAND JOURNAL OF MEDICINE

CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo

(2016) Li-Chung Tsao et al.   Retrovirology

Membrane dynamics associated with viral infection

(2016) Laura de Armas-Rillo et al.   REVIEWS IN MEDICAL VIROLOGY

Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport

(2016) Pablo Mardones et al.   Science Signaling

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

(2016) Brian J. DeBosch et al.   Science Signaling

The Life-Cycle of the HIV-1 Gag–RNA Complex

(2016) Elodie Mailler et al.   Viruses-Basel

Methamphetamine potentiates HIV-1 gp120-mediated autophagy via Beclin-1 and Atg5/7 as a pro-survival response in astrocytes

(2016) Lu Cao et al.   Cell Death & Disease

Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport

(2016) Pablo Mardones et al.   Science Signaling

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

(2016) Brian J. DeBosch et al.   Science Signaling

Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity

(2016) Aram Nikolai Andersen et al.   Frontiers in Immunology

HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART

(2016) Jintanat Ananworanich et al.   EBioMedicine

HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy

(2015) Sophie Borel et al.   AIDS

WHAMM links actin assembly via the Arp2/3 complex to autophagy

(2015) David J Kast et al.   Autophagy

Atg1 family kinases in autophagy initiation

(2015) Nobuo N. Noda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism

(2015) David J. Kast et al.   CURRENT BIOLOGY

HIV-1 gp120: A Target for Therapeutics and Vaccine Design

(2015) Claudia Cicala et al.   CURRENT DRUG TARGETS

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Pharmacologic agents targeting autophagy

(2015) Helin Vakifahmetoglu-Norberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism

(2015) Rushika M. Perera et al.   NATURE

CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation membrane

(2015) Na Mi et al.   NATURE CELL BIOLOGY

Innate immunity against HIV-1 infection

(2015) Marcus Altfeld et al.   NATURE IMMUNOLOGY

HIV-1 assembly, release and maturation

(2015) Eric O. Freed   NATURE REVIEWS MICROBIOLOGY

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

Viremic Relapse after HIV-1 Remission in a Perinatally Infected Child

(2015) Katherine Luzuriaga et al.   NEW ENGLAND JOURNAL OF MEDICINE

Beclin 1 regulates growth factor receptor signaling in breast cancer

(2015) R A Rohatgi et al.   ONCOGENE

Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice

(2015) Alonso Heredia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif autophagic degradation

(2015) María-Soledad Valera et al.   Retrovirology

The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA

(2015) Weijun Zhu et al.   Retrovirology

Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex

(2015) Shiqian Qi et al.   STRUCTURE

Viruses and the autophagy pathway

(2015) William T. Jackson   VIROLOGY

Actin nucleation by WH2 domains at the autophagosome

(2015) Amanda S. Coutts et al.   Nature Communications

CCR5Δ32 mutation and HIV infection: basis for curative HIV therapy

(2015) Kristina Allers et al.   Current Opinion in Virology

Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration

(2015) Grant R. Campbell et al.   PLoS Pathogens

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

(2015) Ole S. Søgaard et al.   PLoS Pathogens

Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure

(2015) Seth M. Dever et al.   Frontiers in Microbiology

HIV infection

(2015) Steven G. Deeks et al.   Nature Reviews Disease Primers

Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

(2015) Hao Tang et al.   EBioMedicine

WIPI-Mediated Autophagy and Longevity

(2015) Mona Grimmel et al.   Cells

TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction

(2015) Michael A Mandell et al.   Autophagy

Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation

(2014) Timothy J. Henrich et al.   ANNALS OF INTERNAL MEDICINE

What is the role of autophagy in HIV-1 infection?

(2014) Lucile Espert et al.   Autophagy

HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells

(2014) Mélanie Denizot et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Autophagy activation by NFκB is essential for cell survival after heat shock

(2014) Mathieu Nivon et al.   Autophagy

Combined autophagy and proteasome inhibition

(2014) Dan T Vogl et al.   Autophagy

Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients

(2014) Roberta Nardacci et al.   Autophagy

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses

(2014) Qiming Liang et al.   Cell Host & Microbe

Self and Nonself: How Autophagy Targets Mitochondria and Bacteria

(2014) Felix Randow et al.   Cell Host & Microbe

TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition

(2014) Michael A. Mandell et al.   DEVELOPMENTAL CELL

Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics

(2014) Anna-Liisa Levonen et al.   FREE RADICAL BIOLOGY AND MEDICINE

p62/SQSTM1 synergizes with autophagy for tumor growth in vivo

(2014) H. Wei et al.   GENES & DEVELOPMENT

CRISPR/Cas9 for genome editing: progress, implications and challenges

(2014) F. Zhang et al.   HUMAN MOLECULAR GENETICS

Evolution of HIV-1 quasispecies and coreceptor use in cell reservoirs of patients on suppressive antiretroviral therapy

(2014) S. Raymond et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

PI4P5-Kinase I  Is Required for Efficient HIV-1 Entry and Infection of T Cells

(2014) M. Barrero-Villar et al.   JOURNAL OF IMMUNOLOGY

Tat-Induced FOXO3a Is a Key Mediator of Apoptosis in HIV-1-Infected Human CD4+ T Lymphocytes

(2014) A. Dabrowska et al.   JOURNAL OF IMMUNOLOGY

Autophagy Restricts HIV-1 Infection by Selectively Degrading Tat in CD4+T Lymphocytes

(2014) Sophie Sagnier et al.   JOURNAL OF VIROLOGY

HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse

(2014) Nazira El-Hage et al.   JOURNAL OF VIROLOGY

RETRACTED ARTICLE: An infectious molecular clone in early infection with HIV-1 subtype CRF01_AE strains: construction and biological properties

(2014) Hong-Wei Wang et al.   MOLECULAR BIOLOGY REPORTS

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

(2014) Hannah C. Dooley et al.   MOLECULAR CELL

Stabilized Human TRIM5α Protects Human T Cells From HIV-1 Infection

(2014) Max W Richardson et al.   MOLECULAR THERAPY

HIV-1 persistence in CD4+ T cells with stem cell–like properties

(2014) Maria J Buzon et al.   NATURE MEDICINE

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

(2014) C Korin Bullen et al.   NATURE MEDICINE

Shift of HIV Tropism in Stem-Cell Transplantation with CCR5 Delta32 Mutation

(2014) Lambros Kordelas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

(2014) Nancy PY Chung et al.   Retrovirology

Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors

(2014) J. M. M. Levy et al.   Cancer Discovery

Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations

(2014) A. Yang et al.   Cancer Discovery

Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy

(2014) Julian H. Elliott et al.   PLoS Pathogens

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

(2014) Thomas A Rasmussen et al.   Lancet HIV

A systematic review of definitions of extreme phenotypes of HIV control and progression

(2013) Deepti Gurdasani et al.   AIDS

Dissecting the role of the Atg12–Atg5-Atg16 complex during autophagosome formation

(2013) Marta Walczak et al.   Autophagy

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons

(2013) Karen Castillo et al.   Autophagy

Proteomics analysis of autophagy-deficient Atg7−/− MEFs reveals a close relationship between F-actin and autophagy

(2013) Cuiqin Zhuo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diverse Autophagosome Membrane Sources Coalesce in Recycling Endosomes

(2013) Claudia Puri et al.   CELL

Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria

(2013) Jamaal L. Benjamin et al.   Cell Host & Microbe

Inhibition of human immunodeficiency virus type-1 through autophagy

(2013) Grant R Campbell et al.   CURRENT OPINION IN MICROBIOLOGY

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

(2013) J. Y. Guo et al.   GENES & DEVELOPMENT

Human β defensin-3 induces chemokines from monocytes and macrophages: diminished activity in cells from HIV-infected persons

(2013) Velizar Petrov et al.   IMMUNOLOGY

Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation

(2013) Helene Knævelsrud et al.   JOURNAL OF CELL BIOLOGY

Kaposi's Sarcoma-Associated Herpesvirus K7 Modulates Rubicon-Mediated Inhibition of Autophagosome Maturation

(2013) Q. Liang et al.   JOURNAL OF VIROLOGY

Quantitative Proteomics Reveals the Induction of Mitophagy in Tumor Necrosis Factor-α-activated (TNFα) Macrophages

(2013) Christina Bell et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Identification of a Cluster of HIV-1 Controllers Infected with Low Replicating Viruses

(2013) Concepción Casado et al.   PLoS One

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

(2013) Philippe Colin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gelsolin activity controls efficient early HIV-1 infection

(2013) Laura García-Expósito et al.   Retrovirology

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism

(2013) Hironori Suzuki et al.   STRUCTURE

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

HIV: Cell Binding and Entry

(2013) C. B. Wilen et al.   Cold Spring Harbor Perspectives in Medicine

HIV entry: a game of hide-and-fuse?

(2013) Gregory B Melikyan   Current Opinion in Virology

24 Hours in the Life of HIV-1 in a T Cell Line

(2013) Pejman Mohammadi et al.   PLoS Pathogens

Sustained Autophagy Contributes to Measles Virus Infectivity

(2013) Clémence Richetta et al.   PLoS Pathogens

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

Autophagy and RNA virus interactomes reveal IRGM as a common target

(2012) Isabel Pombo Grégoire et al.   Autophagy

The actin cytoskeleton participates in the early events of autophagosome formation upon starvation induced autophagy

(2012) Milton Osmar Aguilera et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Recycling endosomes contribute to autophagosome formation

(2012) Andrea Longatti et al.   Autophagy

Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway

(2012) S.-K. Tey et al.   BLOOD

Virus Recognition by Toll-7 Activates Antiviral Autophagy in Drosophila

(2012) Margaret Nakamoto et al.   IMMUNITY

ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex

(2012) Endalkachew Ashenafi Alemu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D

(2012) Kevin Moreau et al.   JOURNAL OF CELL BIOLOGY

Atg9 vesicles are an important membrane source during early steps of autophagosome formation

(2012) Hayashi Yamamoto et al.   JOURNAL OF CELL BIOLOGY

NF- B regulates protein quality control after heat stress through modulation of the BAG3-HspB8 complex

(2012) M. Nivon et al.   JOURNAL OF CELL SCIENCE

Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors

(2012) Julia JM Eekels et al.   Virology Journal

Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs

(2012) Robert W. Buckheit et al.   Nature Communications

Reaping the prevention benefits of highly active antiretroviral treatment

(2012) Andrew D. Forsyth et al.   Current Opinion in HIV and AIDS

Toll-Like Receptor 8 Ligands Activate a Vitamin D Mediated Autophagic Response that Inhibits Human Immunodeficiency Virus Type 1

(2012) Grant R. Campbell et al.   PLoS Pathogens

Vitamin D Inhibits Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis Infection in Macrophages through the Induction of Autophagy

(2012) Grant R. Campbell et al.   PLoS Pathogens

Dual role of autophagy in HIV-1 replication and pathogenesis

(2012) M Killian   AIDS Research and Therapy

Macroautophagy Regulation during HIV-1 Infection of CD4+ T Cells and Macrophages

(2012) Sophie Borel et al.   Frontiers in Immunology

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Regulation and Function of Uncoordinated-51 Like Kinase Proteins

(2011) Edmond Y. Chan   ANTIOXIDANTS & REDOX SIGNALING

Dissecting the involvement of LC3B and GATE-16 in p62 recruitment into autophagosomes

(2011) Elena Shvets et al.   Autophagy

Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation

(2011) Mario Mauthe et al.   Autophagy

Immunogenic and tolerogenic signatures in human immunodeficiency virus (HIV)-infected controllers compared with progressors and a conversion strategy of virus control

(2011) T. Whittall et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

LC3 and GATE-16 N Termini Mediate Membrane Fusion Processes Required for Autophagosome Biogenesis

(2011) Hilla Weidberg et al.   DEVELOPMENTAL CELL

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

(2011) Qingyuan Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LIM Kinase 1 Modulates Cortical Actin and CXCR4 Cycling and Is Activated by HIV-1 to Initiate Viral Infection

(2011) Paul J. Vorster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hormonally Active Vitamin D3 (1α,25-Dihydroxycholecalciferol) Triggers Autophagy in Human Macrophages That Inhibits HIV-1 Infection

(2011) Grant R. Campbell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases

(2011) Shephali Bhatnagar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

(2011) Margalida Rotger et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis

(2011) Dejiang Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation

(2011) Mary Ann Checkley et al.   JOURNAL OF MOLECULAR BIOLOGY

HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA

(2011) Ankit Shah et al.   Journal of Neuroinflammation

HIV-1 co-receptor usage:influence on mother-to-child transmission and pediatric infection

(2011) Mariangela Cavarelli et al.   Journal of Translational Medicine

The Human Cytomegalovirus Protein TRS1 Inhibits Autophagy via Its Interaction with Beclin 1

(2011) M. Chaumorcel et al.   JOURNAL OF VIROLOGY

Programmed neuronal cell death induced by HIV-1 tat and methamphetamine

(2011) Li Qi et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Heat shock protein 90–mediated inactivation of nuclear factor-κB switches autophagy to apoptosis through becn1 transcriptional inhibition in selenite-induced NB4 cells

(2011) Qian Jiang et al.   MOLECULAR BIOLOGY OF THE CELL

HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes

(2011) Laura García-Expósito et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

HIV-1 gp120 Induces Expression of IL-6 through a Nuclear Factor-Kappa B-Dependent Mechanism: Suppression by gp120 Specific Small Interfering RNA

(2011) Ankit Shah et al.   PLoS One

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

How HIV Takes Advantage of the Cytoskeleton in Entry and Replication

(2011) Bettina Stolp et al.   Viruses-Basel

The Sydney Blood Bank Cohort: implications for viral fitness as a cause of elite control

(2011) John Zaunders et al.   Current Opinion in HIV and AIDS

HIV/AIDS, chronic diseases and globalisation

(2011) Christopher J Colvin   Globalization and Health

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

(2011) Isabel Pombo Grégoire et al.   PLoS Pathogens

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

(2010) Hannah E.J. Polson et al.   Autophagy

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

(2010) F. Liu et al.   BLOOD

Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation

(2010) K. Allers et al.   BLOOD

The effects of the 32-bp CCR-5 deletion on HIV transmission and HIV disease progression in individuals with haemophilia

(2010) K. J. Pasi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

(2010) Anthony Orvedahl et al.   Cell Host & Microbe

Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4+T Cells in HIV Elite Controllers

(2010) B. Julg et al.   CLINICAL INFECTIOUS DISEASES

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Fighting disease by selective autophagy of aggregate-prone proteins

(2010) Helene Knaevelsrud et al.   FEBS LETTERS

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses

(2010) Fabien P. Blanchet et al.   IMMUNITY

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

(2010) Marisa Ponpuak et al.   IMMUNITY

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

(2010) Sabrina Di Bartolomeo et al.   JOURNAL OF CELL BIOLOGY

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

(2010) Muriel Mari et al.   JOURNAL OF CELL BIOLOGY

Human immunodeficiency virus type 1 long-term non-progressors: the viral, genetic and immunological basis for disease non-progression

(2010) K. Poropatich et al.   JOURNAL OF GENERAL VIROLOGY

HIV-1 Continues To Replicate and Evolve in Patients with Natural Control of HIV Infection

(2010) H. Mens et al.   JOURNAL OF VIROLOGY

Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus

(2010) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

ADP-Ribosylation Factor 6 Regulates Mammalian Myoblast Fusion through Phospholipase D1 and Phosphatidylinositol 4,5-Bisphosphate Signaling Pathways

(2010) Anne-Sophie Bach et al.   MOLECULAR BIOLOGY OF THE CELL

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea

(2010) Luciano A. Marraffini et al.   NATURE REVIEWS GENETICS

Host and Viral Genetic Correlates of Clinical Definitions of HIV-1 Disease Progression

(2010) Concepción Casado et al.   PLoS One

HIV-1 Inhibits Autophagy in Bystander Macrophage/Monocytic Cells through Src-Akt and STAT3

(2010) Jennifer Van Grol et al.   PLoS One

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

(2010) Maria Salgado et al.   Retrovirology

Revisiting HIV-1 uncoating

(2010) Nathalie Arhel   Retrovirology

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

CRISPR/Cas, the Immune System of Bacteria and Archaea

(2010) P. Horvath et al.   SCIENCE

MHC presentation via autophagy and how viruses escape from it

(2010) Monique Gannage et al.   Seminars in Immunopathology

Genome-Wide mRNA Expression Correlates of Viral Control in CD4+ T-Cells from HIV-1-Infected Individuals

(2010) Margalida Rotger et al.   PLoS Pathogens

Coreceptors and HIV-1 Pathogenesis

(2010) Paul R. Gorry et al.   Current HIV/AIDS Reports

Human immunodeficiency virus type-1 infection inhibits autophagy

(2009) Dejiang Zhou et al.   AIDS

Persistence of high levels of blood soluble human leukocyte antigen-G is associated with rapid progression of HIV infection

(2009) Julie Lajoie et al.   AIDS

Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV

(2009) Sophie Grabar et al.   AIDS

Altered Bystander Apoptosis Induction and Pathogenesis of Enfuvirtide-Resistant HIV Type 1 Env Mutants

(2009) Himanshu Garg et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

NF-κb facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway

(2009) Yahong Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans

(2009) Yuxia Zhang et al.   CELL

Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells

(2009) S Romano et al.   CELL DEATH AND DIFFERENTIATION

Vesicular trafficking and autophagosome formation

(2009) A Longatti et al.   CELL DEATH AND DIFFERENTIATION

Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy

(2009) Nicolas Dupont et al.   Cell Host & Microbe

Autophagy Induction by the Pathogen Receptor CD46

(2009) Pierre-Emmanuel Joubert et al.   Cell Host & Microbe

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Autophagy in disease: a double-edged sword with therapeutic potential

(2009) Wim Martinet et al.   CLINICAL SCIENCE

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

(2009) Jesus F. Salazar-Gonzalez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Persistent Low‐Level Viremia in HIV‐1 Elite Controllers and Relationship to Immunologic Parameters

(2009) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Outcomes of Elite Controllers, Viremic Controllers, and Long‐Term Nonprogressors in the US Department of Defense HIV Natural History Study

(2009) Jason F. Okulicz et al.   JOURNAL OF INFECTIOUS DISEASES

The Heptad Repeat 2 Domain Is a Major Determinant for Enhanced Human Immunodeficiency Virus Type 1 (HIV-1) Fusion and Pathogenicity of a Highly Pathogenic HIV-1 Env

(2009) V. Sivaraman et al.   JOURNAL OF VIROLOGY

p65/RelA Modulates BECN1 Transcription and Autophagy

(2009) T. Copetti et al.   MOLECULAR AND CELLULAR BIOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection

(2009) Lucile Espert et al.   PLoS One

Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects

(2009) Filippo Canducci et al.   Retrovirology

On the steps of cell-to-cell HIV transmission between CD4 T cells

(2009) Isabel Puigdomènech et al.   Retrovirology

HIV Infection of T Cells: Actin-in and Actin-out

(2009) Y. Liu et al.   Science Signaling

mTORC1 Phosphorylates the ULK1-mAtg13-FIP200 Autophagy Regulatory Complex

(2009) E. Y. Chan   Science Signaling

Genetic and antigenic features of the transmitted virus

(2009) Brandon F Keele et al.   Current Opinion in HIV and AIDS

An Initial Step of GAS-Containing Autophagosome-Like Vacuoles Formation Requires Rab7

(2009) Hitomi Yamaguchi et al.   PLoS Pathogens

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

(2008) Masato Koike et al.   AMERICAN JOURNAL OF PATHOLOGY

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

(2008) M. Kundu et al.   BLOOD

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

(2008) Y. Li et al.   CANCER RESEARCH

HIV Envelope-CXCR4 Signaling Activates Cofilin to Overcome Cortical Actin Restriction in Resting CD4 T Cells

(2008) Alyson Yoder et al.   CELL

Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis

(2008) H. Garg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Comparison of Viral Loads between HIV‐1–Infected Elite Suppressors and Individuals Who Receive Suppressive Highly Active Antiretroviral Therapy

(2008) Jason B. Dinoso et al.   CLINICAL INFECTIOUS DISEASES

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

The Atg18-Atg2 Complex Is Recruited to Autophagic Membranes via Phosphatidylinositol 3-Phosphate and Exerts an Essential Function

(2008) Keisuke Obara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages

(2008) Chong-Shan Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes

(2008) M. Barrero-Villar et al.   JOURNAL OF CELL SCIENCE

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Genomewide Association Study of an AIDS‐Nonprogression Cohort Emphasizes the Role Played byHLAGenes (ANRS Genomewide Association Study 02)

(2008) Sophie Limou et al.   JOURNAL OF INFECTIOUS DISEASES

Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy

(2008) H. Hatano et al.   JOURNAL OF VIROLOGY

Monitoring Early Fusion Dynamics of Human Immunodeficiency Virus Type 1 at Single-Molecule Resolution

(2008) T. M. Dobrowsky et al.   JOURNAL OF VIROLOGY

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

(2008) Jelena Nedjic et al.   NATURE

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY

Transcription factor FOXO3a controls the persistence of memory CD4+ T cells during HIV infection

(2008) Julien van Grevenynghe et al.   NATURE MEDICINE

HIV-1 with Multiple CCR5/CXCR4 Chimeric Receptor Use Is Predictive of Immunological Failure in Infected Children

(2008) Mariangela Cavarelli et al.   PLoS One

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions

(2008) Agustín Valenzuela-Fernández et al.   TRENDS IN CELL BIOLOGY