Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage

Methotrexate preferentially affects Tc1 and Tc17 subset of CD8 T lymphocytes

(2018) Amit Sandhu et al.   CLINICAL RHEUMATOLOGY

Evolution of Host Target Cell Specificity During HIV-1 Infection

(2018) Olivia D. Council et al.   CURRENT HIV RESEARCH

Impact of cellular restriction gene (TRIM5α, BST-2) polymorphisms on the acquisition of HIV-1 and disease progression

(2018) HariOm Singh et al.   JOURNAL OF GENE MEDICINE

Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations

(2018) Chitra Upadhyay et al.   PLoS Pathogens

Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane

(2018) Toshana L. Foster et al.   Frontiers in Immunology

Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications

(2017) Maria Paz Gonzalez-Perez et al.   JOURNAL OF VIROLOGY

A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques

(2017) Andrew T. Jones et al.   JOURNAL OF VIROLOGY

HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded

(2017) Briana Quitadamo et al.   JOURNAL OF VIROLOGY

Effects of Amprenavir on HIV-1 Maturation, Production and Infectivity Following Drug Withdrawal in Chronically-Infected Monocytes/Macrophages

(2017) Ana Borrajo et al.   Viruses-Basel

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir

(2017) Claudia R. Avalos et al.   mBio

CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo

(2017) Nadia T. Sebastian et al.   PLoS Pathogens

RNA flow cytometric FISH for investigations into HIV immunology, vaccination and cure strategies

(2017) Amy E. Baxter et al.   AIDS Research and Therapy

Evolutionary Analysis of HIV-1 Pol Proteins Reveals Representative Residues for Viral Subtype Differentiation

(2017) Shohei Nagata et al.   Frontiers in Microbiology

Role of Monocyte/Macrophages during HIV/SIV Infection in Adult and Pediatric Acquired Immune Deficiency Syndrome

(2017) Kristen M. Merino et al.   Frontiers in Immunology

Modulation of apoptosis and viral latency – an axis to be well understood for successful cure of human immunodeficiency virus

(2016) Uddhav Timilsina et al.   JOURNAL OF GENERAL VIROLOGY

Toll-Like Receptor 2 Ligation Enhances HIV-1 Replication in Activated CCR6 + CD4 + T Cells by Increasing Virus Entry and Establishing a More Permissive Environment to Infection

(2016) Jean-François Bolduc et al.   JOURNAL OF VIROLOGY

Humoral Immune Pressure Selects for HIV-1 CXC-chemokine Receptor 4-using Variants

(2016) Nina Lin et al.   EBioMedicine

Eradication of HIV-1 from the Macrophage Reservoir: An Uncertain Goal?

(2015) Wasim Abbas et al.   Viruses-Basel

Changes in HIV reservoirs during long-term antiretroviral therapy

(2015) Feiyu F. Hong et al.   Current Opinion in HIV and AIDS

Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury

(2014) Yedidya Saiman et al.   HEPATOLOGY RESEARCH

RETRACTED ARTICLE: An infectious molecular clone in early infection with HIV-1 subtype CRF01_AE strains: construction and biological properties

(2014) Hong-Wei Wang et al.   MOLECULAR BIOLOGY REPORTS

Early treatment may not be early enough

(2014) Kai Deng et al.   NATURE

Opening Fronts in HIV Vaccine Development: Targeting reservoirs to clear and cure

(2014) Robert F Siliciano   NATURE MEDICINE

HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-κB pathway

(2013) Ryusho Kariya et al.   CANCER LETTERS

Human β defensin-3 induces chemokines from monocytes and macrophages: diminished activity in cells from HIV-infected persons

(2013) Velizar Petrov et al.   IMMUNOLOGY

The p38 MAPK NF-κB pathway, not the ERK pathway, is involved in exogenous HIV-1 Tat-induced apoptotic cell death in retinal pigment epithelial cells

(2013) Ling Bai et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Some mechanisms of FLIP expression in inhibition of HIV-1 replication in Jurkat cells, CD4+ T cells and PBMCs

(2013) Jiying Tan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TNF and TNF Receptor Superfamily Members in HIV infection: New Cellular Targets for Therapy?

(2013) Amit Kumar et al.   MEDIATORS OF INFLAMMATION

HIV-1 transcription and latency: an update

(2013) Carine Van Lint et al.   Retrovirology

Altering cell death pathways as an approach to cure HIV infection

(2013) A D Badley et al.   Cell Death & Disease

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors

(2012) Paul J Peters et al.   Retrovirology

Molecules from apoptotic pathways modulate HIV-1 replication in Jurkat cells

(2011) Xue Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation of a Fluorescent Derivative of AMD3100 and its Interaction with the CXCR4 Chemokine Receptor

(2011) James C. Knight et al.   CHEMBIOCHEM

HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation

(2011) Mary Ann Checkley et al.   JOURNAL OF MOLECULAR BIOLOGY

Alternative Coreceptor Requirements for Efficient CCR5- and CXCR4-Mediated HIV-1 Entry into Macrophages

(2011) K. Cashin et al.   JOURNAL OF VIROLOGY

Human immunodeficiency virus type 1 long-term non-progressors: the viral, genetic and immunological basis for disease non-progression

(2010) K. Poropatich et al.   JOURNAL OF GENERAL VIROLOGY

Impact of γ-chain cytokines on T cell homeostasis in HIV-1 infection: therapeutic implications

(2010) M.-L. Gougeon et al.   JOURNAL OF INTERNAL MEDICINE

Macrophage signaling in HIV-1 infection

(2010) Georges Herbein et al.   Retrovirology

Coreceptors and HIV-1 Pathogenesis

(2010) Paul R. Gorry et al.   Current HIV/AIDS Reports

Heterosexual Transmission of Human Immunodeficiency Virus Type 1 Subtype C: Macrophage Tropism, Alternative Coreceptor Use, and the Molecular Anatomy of CCR5 Utilization

(2009) J. Isaacman-Beck et al.   JOURNAL OF VIROLOGY

The Challenge of Finding a Cure for HIV Infection

(2009) D. D. Richman et al.   SCIENCE