Coreceptors and HIV-1 Pathogenesis

Dual-tropic HIV type 1 isolates vary dramatically in their utilization of CCR5 and CXCR4 coreceptors

(2010) Jonathan Toma et al.   AIDS

HIV Type 1 from a Patient with Baseline Resistance to CCR5 Antagonists Uses Drug-Bound Receptor for Entry

(2010) John C. Tilton et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Viral tropism, fitness and pathogenicity of HIV-1 subtype C

(2010) Martin R Jakobsen et al.   Future Virology

Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses

(2010) Fabien P. Blanchet et al.   IMMUNITY

Editorial: Monocyte subpopulations and lentiviral infection

(2010) Suzanne M. Crowe et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV-1 Resistance to CCR5 Antagonists Associated with Highly Efficient Use of CCR5 and Altered Tropism on Primary CD4+ T Cells

(2010) J. M. Pfaff et al.   JOURNAL OF VIROLOGY

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

Host hindrance to HIV-1 replication in monocytes and macrophages

(2010) Anna Bergamaschi et al.   Retrovirology

Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection

(2010) Gabriel Gras et al.   Retrovirology

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Constrained use of CCR5 on CD4+ lymphocytes by R5X4 HIV-1: Efficiency of Env–CCR5 interactions and low CCR5 expression determine a range of restricted CCR5-mediated entry

(2010) Lamorris M. Loftin et al.   VIROLOGY

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

(2010) Jasminka Sterjovski et al.   VIROLOGY

Th17 lineage commitment and HIV-1 pathogenesis

(2010) Petronela Ancuta et al.   Current Opinion in HIV and AIDS

IFN-α-Induced Upregulation of CCR5 Leads to Expanded HIV Tropism In Vivo

(2010) Cheryl A. Stoddart et al.   PLoS Pathogens

A Novel CCR5 Mutation Common in Sooty Mangabeys Reveals SIVsmm Infection of CCR5-Null Natural Hosts and Efficient Alternative Coreceptor Use In Vivo

(2010) Nadeene E. Riddick et al.   PLoS Pathogens

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

(2009) A. Gosselin et al.   JOURNAL OF IMMUNOLOGY

Tissue-Specific Sequence Alterations in the Human Immunodeficiency Virus Type 1 Envelope Favoring CCR5 Usage Contribute to Persistence of Dual-Tropic Virus in the Brain

(2009) L. Gray et al.   JOURNAL OF VIROLOGY

Determinants Flanking the CD4 Binding Loop Modulate Macrophage Tropism of Human Immunodeficiency Virus Type 1 R5 Envelopes

(2009) M. J. Duenas-Decamp et al.   JOURNAL OF VIROLOGY

Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection

(2009) R. Shen et al.   JOURNAL OF VIROLOGY

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41

(2009) C. G. Anastassopoulou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1

(2009) A. Benlahrech et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The integrin  4 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

(2009) C. Cicala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative 3D Video Microscopy of HIV Transfer Across T Cell Virological Synapses

(2009) W. Hubner et al.   SCIENCE

Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities

(2009) Pavel Pugach et al.   VIROLOGY

Enhanced CD4+ cellular apoptosis by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with progressive HIV-1 infection

(2009) Jessica Wade et al.   VIROLOGY

Two HIV-1 Variants Resistant to Small Molecule CCR5 Inhibitors Differ in How They Use CCR5 for Entry

(2009) Reem Berro et al.   PLoS Pathogens

Autocrine Production of β-Chemokines Protects CMV-Specific CD4+ T Cells from HIV Infection

(2009) Joseph P. Casazza et al.   PLoS Pathogens

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Evolution of CCR5 Use before and during Coreceptor Switching

(2008) M. Coetzer et al.   JOURNAL OF VIROLOGY

Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients

(2008) Petronela Ancuta et al.   PLoS One