Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis
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Title
Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis
Authors
Keywords
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Journal
Cells
Volume 9, Issue 4, Pages 964
Publisher
MDPI AG
Online
2020-04-15
DOI
10.3390/cells9040964
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Note: Only part of the references are listed.- Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview
- (2019) Simona Marchisello et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2019) Sebastian Prill et al. Scientific Reports
- Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease
- (2018) Juan Pablo Arab et al. Annual Review of Pathology-Mechanisms of Disease
- Cytochrome P450S and Alcoholic Liver Disease
- (2018) Yongke Lu et al. CURRENT PHARMACEUTICAL DESIGN
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- (2018) Stephen A. Harrison et al. GASTROENTEROLOGY
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- (2018) Benaïssa Boubia et al. JOURNAL OF MEDICINAL CHEMISTRY
- Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions
- (2018) Sabine U Vorrink et al. TOXICOLOGICAL SCIENCES
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- (2018) Andrey Poloznikov ALTEX-Alternatives to Animal Experimentation
- Three-Dimensional Spheroid Primary Human Hepatocytes in Monoculture and Coculture with Nonparenchymal Cells
- (2018) Audrey Baze et al. TISSUE ENGINEERING PART C-METHODS
- Human hepatic 3D spheroids as a model for steatosis and insulin resistance
- (2018) Mikael Kozyra et al. Scientific Reports
- AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis
- (2018) Isabel Cordero-Herrera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-alcoholic fatty liver disease (NAFLD) models in drug discovery
- (2017) Banumathi K. Cole et al. Expert Opinion on Drug Discovery
- Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics
- (2017) Sabine U. Vorrink et al. FASEB JOURNAL
- Current and future pharmacological therapies for NAFLD/NASH
- (2017) Yoshio Sumida et al. JOURNAL OF GASTROENTEROLOGY
- Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System
- (2017) Kazuhiro Tetsuka et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
- (2017) Kelly L. Walton et al. Frontiers in Pharmacology
- Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis
- (2017) Vincenzo Prestigiacomo et al. PLoS One
- Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates
- (2016) Volker M. Lauschke et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances
- (2016) Jennie Ka Ching Lau et al. JOURNAL OF PATHOLOGY
- Editor’s Highlight: Modeling Compound-Induced FibrogenesisIn VitroUsing Three-Dimensional Bioprinted Human Liver Tissues
- (2016) Leah M. Norona et al. TOXICOLOGICAL SCIENCES
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- (2016) Deborah G. Nguyen et al. PLoS One
- Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response
- (2016) Shyam Sundhar Bale et al. Scientific Reports
- Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
- (2016) Catherine C. Bell et al. Scientific Reports
- Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability
- (2016) Delilah F. G. Hendriks et al. Scientific Reports
- The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation
- (2015) Pablo J. Giraudi et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Cytochrome P450–dependent metabolism of ω-6 and ω-3 long-chain polyunsaturated fatty acids
- (2014) Cosima Arnold et al. Pharmacological Reports
- The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts
- (2014) Kirsten Linhart et al. Redox Biology
- The global NAFLD epidemic
- (2013) Rohit Loomba et al. Nature Reviews Gastroenterology & Hepatology
- Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology
- (2013) Ingmar Mederacke et al. Nature Communications
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- (2012) H. Qin et al. JOURNAL OF HEPATOLOGY
- Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
- (2012) Mohamed A. Abdelmegeed et al. JOURNAL OF HEPATOLOGY
- TGF-β in progression of liver disease
- (2011) Steven Dooley et al. CELL AND TISSUE RESEARCH
- Introducing intermediate filaments: from discovery to disease
- (2009) John E. Eriksson et al. JOURNAL OF CLINICAL INVESTIGATION
- Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance
- (2009) S. Kidambi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of CD68 in Non-Myeloid Cell Types
- (2008) E. Gottfried et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
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