Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways

Effect of kirenol on the interaction between the WNT/β-Catenin and RUNX2/TCF/LEF1 pathways in fracture healing in vivo

(2020) Ibrahim Karaman et al.   Acta Orthopaedica et Traumatologica Turcica

Natural compounds against doxorubicin‐induced cardiotoxicity: A review on the involvement of Nrf2/ ARE signaling pathway

(2020) Fatemeh Yarmohammadi et al.   PHYTOTHERAPY RESEARCH

Orosomucoid 1 Attenuates Doxorubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes via Nrf2 Signaling

(2020) Xiaoli Cheng et al.   Biomed Research International

Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies

(2020) Peramaiyan Rajendran et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Detection of BPDE-DNA adducts in human umbilical cord blood by LC-MS/MS analysis

(2019) Ling Guo et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Chitosan oligosaccharides prevent doxorubicin-induced oxidative stress and cardiac apoptosis through activating p38 and JNK MAPK mediated Nrf2/ARE pathway

(2019) Yongtian Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia–Reoxygenation

(2019) Ping Yang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Anti-EMT properties of CoQ0 attributed to PI3K/AKT/NFKB/MMP-9 signaling pathway through ROS-mediated apoptosis

(2019) Hsin-Ling Yang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT

(2019) Xin Zhang et al.   CELL DEATH AND DIFFERENTIATION

Oxidative stress injury in doxorubicin-induced cardiotoxicity

(2019) Mei Songbo et al.   TOXICOLOGY LETTERS

Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo

(2019) Jing Wu et al.   Frontiers in Immunology

Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model

(2019) Bin Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates d-Galactose-Induced Brain Aging in Mice

(2019) Peng Chen et al.   Neurotherapeutics

Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway

(2019) Hailiang Yu et al.   Artificial Cells Nanomedicine and Biotechnology

Anti-inflammatory activities of Sigesbeckia glabrescens Makino: combined in vitro and in silico investigations

(2019) Zhangfeng Zhong et al.   Chinese Medicine

Impact of Arterial Hypertension on Doxorubicin-Based Chemotherapy-Induced Subclinical Cardiac Damage in Breast Cancer Patients

(2019) Domas Vaitiekus et al.   Cardiovascular Toxicology

Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP

(2019) Shawn H. Reginauld et al.   JACC-Heart Failure

Doxorubicin‐induces NFAT/Fas/FasL cardiac apoptosis in rats through activation of calcineurin and P38 MAPK and inhibition of mTOR signalling pathways

(2019) Ali A. Shati   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

p -Coumaric acid mediated protection of H9c2 cells from Doxorubicin-induced cardiotoxicity: Involvement of augmented Nrf2 and autophagy

(2018) Mary Chacko Sunitha et al.   BIOMEDICINE & PHARMACOTHERAPY

Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways

(2018) Faisal Imam et al.   Pharmacological Reports

Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR

(2018) Christopher Manzella et al.   Scientific Reports

Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway

(2018) Ying Xin et al.   Redox Biology

Protective Effect of Fisetin Against angiotensin II-induced Apoptosis by Activation of IGF-IR-PI3K-Akt Signaling in H9c2 cells and Spontaneous hypertension rats

(2018) Bih-Cheng Chen et al.   PHYTOMEDICINE

Role of the Cytoskeleton in the Development of a Hypofibrotic Cardiac Fibroblast Phenotype in Volume Overload Heart Failure

(2018) Rachel C Childers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats

(2018) Kuan-Ho Lin et al.   Journal of Functional Foods

Doxorubicin-induced heart failure in cancer patients: A cohort study based on the Korean National Health Insurance Database

(2018) Young Ae Kim et al.   Cancer Medicine

Tanshinone IIA Inhibits β-Catenin Nuclear Translocation and IGF-2R Activation via Estrogen Receptors to Suppress Angiotensin II-Induced H9c2 Cardiomyoblast Cell Apoptosis

(2017) Ya-Fang Chen et al.   International Journal of Medical Sciences

Thioredoxin 2 Offers Protection against Mitochondrial Oxidative Stress in H9c2 Cells and against Myocardial Hypertrophy Induced by Hyperglycemia

(2017) Hong Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neferine modulates IGF-1R/Nrf2 signaling in doxorubicin treated H9c2 cardiomyoblasts

(2017) Lohanathan Bharathi Priya et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protective effect of Co-enzyme Q10 On doxorubicin-induced cardiomyopathy of rat hearts

(2016) Pei-Yu Chen et al.   ENVIRONMENTAL TOXICOLOGY

Regulation of cardiac hypertrophy and remodeling through the dual-specificity MAPK phosphatases (DUSPs)

(2016) Ruijie Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myricitrin Attenuates High Glucose-Induced Apoptosis through Activating Akt-Nrf2 Signaling in H9c2 Cardiomyocytes

(2016) Bin Zhang et al.   MOLECULES

Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death

(2016) Chih-Yang Huang et al.   Cell Death & Disease

Naringin protects against anoxia/reoxygenation-induced apoptosis in H9c2 cells via the Nrf2 signaling pathway

(2015) R. C. Chen et al.   Food & Function

Kirenol inhibits adipogenesis through activation of the Wnt/β-catenin signaling pathway in 3T3-L1 adipocytes

(2014) Mi-Bo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pre-existing arterial hypertension as a risk factor for early left ventricular systolic dysfunction following (R)-CHOP chemotherapy in patients with lymphoma

(2014) Sebastian Szmit et al.   Journal of the American Society of Hypertension

The Role of Nrf2-Mediated Pathway in Cardiac Remodeling and Heart Failure

(2014) Shanshan Zhou et al.   Oxidative Medicine and Cellular Longevity

AstragalusPolysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways

(2014) Yuan Cao et al.   Oxidative Medicine and Cellular Longevity

Radical Roles for RAGE in the Pathogenesis of Oxidative Stress in Cardiovascular Diseases and Beyond

(2013) Gurdip Daffu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulation of cardiac autophagy by insulin-like growth factor 1

(2013) Rodrigo Troncoso et al.   IUBMB LIFE

Cardiomyocyte autophagy and cancer chemotherapy

(2013) Dan L. Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Diet-relevant phytochemical intake affects the cardiac AhR and nrf2 transcriptome and reduces heart failure in hypertensive rats

(2013) E. Mitchell Seymour et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways

(2012) Jian Ma et al.   CARDIOVASCULAR RESEARCH

Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance

(2012) Yue Lu et al.   PHYTOMEDICINE

Oxidative stress and heart failure

(2011) Hiroyuki Tsutsui et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK

(2011) Joydeep Das et al.   BIOCHEMICAL PHARMACOLOGY

Simultaneous quantification of eight major constituents in Herba Siegesbeckiae by liquid chromatography coupled with electrospray ionization time-of-flight tandem mass spectrometry

(2011) Zhen Jiang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Constitutive Activation of Caspase-3 and Poly ADP Ribose Polymerase Cleavage in Fanconi Anemia Cells

(2010) A. Lyakhovich et al.   MOLECULAR CANCER RESEARCH

p38 MAPK and JNK Antagonistically Control Senescence and Cytoplasmic p16INK4A Expression in Doxorubicin-Treated Endothelial Progenitor Cells

(2010) Paolo Spallarossa et al.   PLoS One

Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure

(2008) Lihe Lu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY