Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo

RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes

(2018) Jing Wu et al.   BMC MUSCULOSKELETAL DISORDERS

Diagnosis and Management of Rheumatoid Arthritis

(2018) Daniel Aletaha et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Piperlongumine inhibits the proliferation, migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis

(2017) Siqi Xu et al.   INFLAMMATION RESEARCH

Halofuginone inhibits TNF-α-induced the migration and proliferation of fibroblast-like synoviocytes from rheumatoid arthritis patients

(2017) Shan Zeng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Negative Regulators of JAK/STAT Signaling in Rheumatoid Arthritis and Osteoarthritis

(2017) Charles Malemud   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective Effects of Standardized Siegesbeckia glabrescens Extract and Its Active Compound Kirenol against UVB-Induced Photoaging through Inhibition of MAPK/NF-��B Pathways

(2017) Jongwook Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Pathogenetic insights from the treatment of rheumatoid arthritis

(2017) Iain B McInnes et al.   LANCET

Kirenol Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Differentiation of Th1 and Th17 Cells and Inducing Apoptosis of Effector T Cells

(2015) Juan Xiao et al.   Scientific Reports

Kirenol inhibits adipogenesis through activation of the Wnt/β-catenin signaling pathway in 3T3-L1 adipocytes

(2014) Mi-Bo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors

(2014) C. Sekine et al.   JOURNAL OF IMMUNOLOGY

Tumor Necrosis Factor α Induces Sustained Signaling and a Prolonged and Unremitting Inflammatory Response in Rheumatoid Arthritis Synovial Fibroblasts

(2013) Angela Lee et al.   ARTHRITIS AND RHEUMATISM

Simultaneous quantification of Kirenol and ent-16β,17-dihydroxy-kauran-19-oic acid from Herba Siegesbeckiae in rat plasma by liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies

(2013) Linan Huo et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway

(2012) Guoqing Li et al.   MOLECULAR IMMUNOLOGY

Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance

(2012) Yue Lu et al.   PHYTOMEDICINE

Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes

(2011) A. Hot et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-17 Contributes to Angiogenesis in Rheumatoid Arthritis

(2010) S. R. Pickens et al.   JOURNAL OF IMMUNOLOGY

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

CXCL 9 and CXCL 10 as Sensitive Markers of Disease Activity in Patients with Rheumatoid Arthritis

(2009) W. P. KUAN et al.   JOURNAL OF RHEUMATOLOGY

Remission and rheumatoid arthritis: Data on patients receiving usual care in twenty-four countries

(2008) Tuulikki Sokka et al.   ARTHRITIS AND RHEUMATISM