Doxorubicin‐induces NFAT/Fas/FasL cardiac apoptosis in rats through activation of calcineurin and P38 MAPK and inhibition of mTOR signalling pathways

Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling

(2018) Refaat A. Eid et al.   BASIC RESEARCH IN CARDIOLOGY

Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation

(2018) Muhammad S. Alam et al.   PLOS BIOLOGY

Calcineurin/NFAT Signaling Modulates Pulmonary Artery Smooth Muscle Cell Proliferation, Migration and Apoptosis in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats

(2018) Rui-Lan He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

mTORC1 Inhibits NF-κB/NFATc1 Signaling and Prevents Osteoclast Precursor Differentiation, In Vitro and In Mice

(2017) Yue Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of cell death in the progression of heart failure

(2016) Gordon W. Moe et al.   HEART FAILURE REVIEWS

Protective Effect of Dietary Ghrelin-Containing Salmon Stomach Extract on Mortality and Cardiotoxicity in Doxorubicin-Induced Mouse Model of Heart Failure

(2016) Minoru Kihara et al.   JOURNAL OF FOOD SCIENCE

Nuclear factor of activated T cells in cancer development and treatment

(2015) Jiawei Shou et al.   CANCER LETTERS

Relaxin protects cardiac muscle cells from hypoxia/reoxygenation injury: involvement of the Notch-1 pathway

(2015) Giulia Boccalini et al.   FASEB JOURNAL

Serum Biomarkers for the Detection of Cardiac Toxicity after Chemotherapy and Radiation Therapy in Breast Cancer Patients

(2014) Sibo Tian et al.   Frontiers in Oncology

Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

(2013) RUN-MIN GUO et al.   Molecular Medicine Reports

Increased Beta2-Adrenoceptors in Doxorubicin-Induced Cardiomyopathy in Rat

(2013) Nolwenn Merlet et al.   PLoS One

Mechanisms of Cell Death in Heart Disease

(2012) Klitos Konstantinidis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model

(2012) Varsha G. Desai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK

(2011) Joydeep Das et al.   BIOCHEMICAL PHARMACOLOGY

General oxidative stress during doxorubicin-induced cardiotoxicity in rats: Absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid

(2011) Steliana Ghibu et al.   BIOCHIMIE

NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy

(2010) Raquel Gómez-Sintes et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of Anthracycline Cardiac Injury: Can We Identify Strategies for Cardioprotection?

(2010) Douglas B. Sawyer et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Anti-Fas Gene Therapy Prevents Doxorubicin-Induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis

(2009) Shusaku Miyata et al.   AMERICAN JOURNAL OF PATHOLOGY

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Doxorubicin Cardiomyopathy

(2009) Kanu Chatterjee et al.   CARDIOLOGY

JNK1/c-Jun and p38α MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells upon exposure to Taiwan cobra phospholipase A2

(2009) Ku-Chung Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Leptin protects H9c2 rat cardiomyocytes from H2O2-induced apoptosis

(2008) Megumi Eguchi et al.   FEBS Journal

Integration of Protein Kinases mTOR and Extracellular Signal-Regulated Kinase 5 in Regulating Nucleocytoplasmic Localization of NFATc4

(2008) T. T. C. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY