Myricitrin Attenuates High Glucose-Induced Apoptosis through Activating Akt-Nrf2 Signaling in H9c2 Cardiomyocytes

β-Caryophyllene, a natural sesquiterpene lactone attenuates hyperglycemia mediated oxidative and inflammatory stress in experimental diabetic rats

(2016) Rafeek Hidhayath Basha et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibiting receptor for advanced glycation end product (AGE) and oxidative stress involved in the protective effect mediated by glucagon-like peptide-1 receptor on AGE induced neuronal apoptosis

(2016) Song Chen et al.   NEUROSCIENCE LETTERS

t-BHQ Provides Protection against Lead Neurotoxicity via Nrf2/HO-1 Pathway

(2016) Fang Ye et al.   Oxidative Medicine and Cellular Longevity

Chebulic acid prevents hepatic fibrosis induced by advanced glycation end-products in LX-2 cell by modulating Nrf2 translocation via ERK pathway

(2016) Yun-Chang Koo et al.   TOXICOLOGY IN VITRO

Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways

(2016) Yingli Yu et al.   Scientific Reports

Aralia taibaiensis Protects Cardiac Myocytes against High Glucose-Induced Oxidative Stress and Apoptosis

(2015) Jialin Duan et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Blockage of ROS and NF-κB-mediated inflammation by a new chalcone L6H9 protects cardiomyocytes from hyperglycemia-induced injuries

(2015) Peng Zhong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Calpain-1 induces endoplasmic reticulum stress in promoting cardiomyocyte apoptosis following hypoxia/reoxygenation

(2015) Dong Zheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Suppression of antioxidant Nrf-2 and downstream pathway in H9c2 cells by advanced glycation end products (AGEs) via ERK phosphorylation

(2015) Shun-Yao Ko et al.   BIOCHIMIE

Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

(2015) Zhongwei Liu et al.   Cardiovascular Diabetology

Inhibiting microRNA-144 abates oxidative stress and reduces apoptosis in hearts of streptozotocin-induced diabetic mice

(2015) Manli Yu et al.   CARDIOVASCULAR PATHOLOGY

Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice

(2015) Robert Domitrović et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis

(2015) Chenglong Dong et al.   EXPERIMENTAL CELL RESEARCH

Fisetin inhibits TNF-α-induced inflammatory action and hydrogen peroxide-induced oxidative damage in human keratinocyte HaCaT cells through PI3K/AKT/Nrf-2-mediated heme oxygenase-1 expression

(2015) Seung-Hee Seo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3

(2015) Pankaj K. Bagul et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Myricitrin attenuates endothelial cell apoptosis to prevent atherosclerosis: An insight into PI3K/Akt activation and STAT3 signaling pathways

(2015) Meng Qin et al.   VASCULAR PHARMACOLOGY

Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway

(2015) Jialin Duan et al.   Scientific Reports

Isorhamnetin Attenuates Atherosclerosis by Inhibiting Macrophage Apoptosis via PI3K/AKT Activation and HO-1 Induction

(2015) Yun Luo et al.   PLoS One

Advanced Glycation End-Products Induce Apoptosis in Pancreatic Islet Endothelial Cells via NF-κB-Activated Cyclooxygenase-2/Prostaglandin E2 Up-Regulation

(2015) Kuo-Cheng Lan et al.   PLoS One

Salidroside inhibits oxygen glucose deprivation (OGD)/re-oxygenation-induced H9c2 cell necrosis through activating of Akt–Nrf2 signaling

(2014) Koulong Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unconjugated Bilirubin Mediates Heme Oxygenase-1–Induced Vascular Benefits in Diabetic Mice

(2014) Jian Liu et al.   DIABETES

Levocarnitine Protects H9c2 Rat Cardiomyocytes from H2O2-induced Mitochondrial Dysfunction and Apoptosis

(2014) Cui-Ying Mao et al.   International Journal of Medical Sciences

Attenuation of Aβ25–35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways

(2014) Xiangbao Meng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Naringin Inhibits ROS-activated MAPK Pathway in High Glucose-induced Injuries in H9c2 Cardiac Cells

(2013) Jingfu Chen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Taxifolin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of oxidative stress and cell apoptosis

(2013) Xiao Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells

(2013) Kaipeng Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis

(2013) Praveen K. Sobhan et al.   PLoS One

Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro

(2013) Jing Sun et al.   PLoS One

Minocycline suppresses oxidative stress and attenuates fetal cardiac myocyte apoptosis triggered by in utero cocaine exposure

(2011) Indrani Sinha-Hikim et al.   APOPTOSIS

Up-regulation of p27kip1 contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy

(2011) Jinqing Li et al.   CARDIOVASCULAR RESEARCH

Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species

(2011) Leila Hosseinzadeh et al.   FOOD AND CHEMICAL TOXICOLOGY

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance

(2011) Rui-Hong Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models

(2011) M. Pereira et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells

(2010) Ying Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress: a key contributor to diabetic cardiomyopathyThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.

(2010) Madhu Khullar et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Cardiac-Specific IGF-1 Receptor Transgenic Expression Protects Against Cardiac Fibrosis and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy

(2010) K. Huynh et al.   DIABETES

Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress

(2009) Jinqing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY