Exosomes and Cell Communication: From Tumour-Derived Exosomes and Their Role in Tumour Progression to the Use of Exosomal Cargo for Cancer Treatment

Exosomes are the Driving Force in Preparing the Soil for the Metastatic Seeds: Lessons from the Prostate Cancer

(2020) Saber H. Saber et al.   Cells

Exosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression

(2020) Xueyan Zang et al.   Cell Death & Disease

Exosomes in head and neck cancer: Roles, mechanisms and applications

(2020) Jun Cao et al.   CANCER LETTERS

Editorial On “Exosomes, Their Biogenesis and Role in Inter-Cellular Communication, Tumor Microenvironment and Cancer Immunotherapy”

(2020) Vita Golubovskaya et al.   Vaccines

Translational Boron Neutron Capture Therapy (BNCT) studies for the treatment of tumors in lung

(2019) V.A. Trivillin et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Intercellular Vesicular Transfer by Exosomes, Microparticles and Oncosomes - Implications for Cancer Biology and Treatments

(2019) Ritu Jaiswal et al.   Frontiers in Oncology

The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression

(2019) Peter Vaupel et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Targeting Tumor Microenvironment for Cancer Therapy

(2019) Catarina Roma-Rodrigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Active Fraction from Embryo Fish Extracts Induces Reversion of the Malignant Invasive Phenotype in Breast Cancer through Down-regulation of TCTP and Modulation of E-cadherin/β-catenin Pathway

(2019) Proietti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance

(2019) Ladan Mashouri et al.   Molecular Cancer

Differential tissue expression of extracellular vesicle‐derived proteins in prostate cancer

(2019) Diederick Duijvesz et al.   PROSTATE

Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era

(2019) Minoru Suzuki   International Journal of Clinical Oncology

The pleiotropic role of proteoglycans in extracellular vesicle mediated communication in the tumor microenvironment

(2019) M. Cerezo-Magaña et al.   SEMINARS IN CANCER BIOLOGY

FZD10 Carried by Exosomes Sustains Cancer Cell Proliferation

(2019) Scavo et al.   Cells

Tumor-derived exosomes, myeloid-derived suppressor cells, and tumor microenvironment

(2019) Xinyu Tian et al.   Journal of Hematology & Oncology

CircRNAs in cancer metabolism: a review

(2019) Tao Yu et al.   Journal of Hematology & Oncology

Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients

(2019) Robin Mjelle et al.   BMC CANCER

Cancer-derived exosomes trigger endothelial to mesenchymal transition followed by the induction of cancer-associated fibroblasts

(2018) Ju Hun Yeon et al.   Acta Biomaterialia

Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

(2018) Yi Yang et al.   CELL RESEARCH

Exosomes and Ectosomes in Intercellular Communication

(2018) Jacopo Meldolesi   CURRENT BIOLOGY

Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation

(2018) Fatima Qadir et al.   Molecular Cancer

Exosomes as a Drug Delivery System in Cancer Therapy: Potential and Challenges

(2018) Golam Kibria et al.   MOLECULAR PHARMACEUTICS

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

(2018) Haiying Zhang et al.   NATURE CELL BIOLOGY

Molecular mechanism to recruit galectin-3 into multivesicular bodies for polarized exosomal secretion

(2018) Sebastian Bänfer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes in cancer: Use them or target them?

(2018) Nuno Bastos et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tumor-derived exosomes, microRNAs, and cancer immune suppression

(2018) Michael W. Graner et al.   Seminars in Immunopathology

Metabolic Kinases Moonlighting as Protein Kinases

(2018) Zhimin Lu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

(2018) Franz L. Ricklefs et al.   Science Advances

The Origin and Functions of Exosomes in Cancer

(2018) Chitra Rajagopal et al.   Frontiers in Oncology

A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission

(2018) Melissa J. Hoyer et al.   CELL

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Exosomes-mediated transfer of long noncoding RNA ZFAS1 promotes gastric cancer progression

(2017) Lei Pan et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells

(2017) Peiming Zheng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Immune Modulatory microRNAs Involved in Tumor Attack and Tumor Immune Escape

(2017) Stefan B. Eichmüller et al.   JNCI-Journal of the National Cancer Institute

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

Syntenin mediates SRC function in exosomal cell-to-cell communication

(2017) Naga Sailaja Imjeti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of exosomes in cancer metastasis

(2017) Teresa Bernadette Steinbichler et al.   SEMINARS IN CANCER BIOLOGY

Out of Warburg effect: An effective cancer treatment targeting the tumor specific metabolism and dysregulated pH

(2017) Laurent Schwartz et al.   SEMINARS IN CANCER BIOLOGY

Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis

(2017) Robert J. Eddy et al.   TRENDS IN CELL BIOLOGY

Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

(2017) Masaki Takasugi et al.   Nature Communications

Immune Modulatory microRNAs Involved in Tumor Attack and Tumor Immune Escape

(2017) Stefan B. Eichmüller et al.   JNCI-Journal of the National Cancer Institute

Functional Roles for Exosomal MicroRNAs in the Tumour Microenvironment

(2017) Emma Bell et al.   Computational and Structural Biotechnology Journal

SCAMP 3 is a novel regulator of endosomal morphology and composition

(2016) Priscilla Thomas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Warburg effect and drug resistance

(2016) Bhaskar Bhattacharya et al.   BRITISH JOURNAL OF PHARMACOLOGY

Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype

(2016) Ling Li et al.   CANCER RESEARCH

How cancer cells dictate their microenvironment: present roles of extracellular vesicles

(2016) Yutaka Naito et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site

(2016) L. Rivoltini et al.   CLINICAL CANCER RESEARCH

Cancer: A Problem of Developmental Biology; Scientific Evidence for Reprogramming and Differentiation Therapy

(2016) Stewart Sell et al.   CURRENT DRUG TARGETS

Exosomes and tumor-mediated immune suppression

(2016) Theresa L. Whiteside   JOURNAL OF CLINICAL INVESTIGATION

Exosome-mediated Transfer of  v 3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype

(2016) A. Singh et al.   MOLECULAR CANCER RESEARCH

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

(2016) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells

(2016) K E Richards et al.   ONCOGENE

Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts

(2016) S Baroni et al.   Cell Death & Disease

Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages

(2016) Xiang Ying et al.   Oncotarget

Curcumin increases exosomal TCF21 thus suppressing exosome-induced lung cancer

(2016) Hao Wu et al.   Oncotarget

Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

(2016) Anna Gutkin et al.   Oncotarget

Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles

(2016) Morad-Rémy Muhsin-Sharafaldine et al.   Oncotarget

YKT6 expression, exosome release, and survival in non-small cell lung cancer

(2016) Marc Ruiz-Martinez et al.   Oncotarget

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

(2016) Hongyun Zhao et al.   eLife

Cells release subpopulations of exosomes with distinct molecular and biological properties

(2016) Eduard Willms et al.   Scientific Reports

Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism

(2015) Stefania Raimondo et al.   Cell Communication and Signaling

Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells

(2015) Pier Biava et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Exosome mediated communication within the tumor microenvironment

(2015) Lara Milane et al.   JOURNAL OF CONTROLLED RELEASE

Nanoscaled boron-containing delivery systems and therapeutic agents for cancer treatment

(2015) Jing Wang et al.   Nanomedicine

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells – Evidence of unique microRNA cargos

(2015) Taral R Lunavat et al.   RNA Biology

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

(2015) Naoomi Tominaga et al.   Nature Communications

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

(2015) Ridwana Chowdhury et al.   Oncotarget

Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

(2015) Valentina R. Minciacchi et al.   Oncotarget

Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p

(2015) Guoping Ding et al.   Oncotarget

Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species

(2015) Serena Rubina Baglio et al.   Stem Cell Research & Therapy

Warburg Effect or Reverse Warburg Effect? A Review of Cancer Metabolism

(2015) Xiao Dong Xu et al.   Oncology Research and Treatment

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC

(2015) Benjamin Besse et al.   OncoImmunology

Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma

(2015) Shu-biao Ye et al.   Oncotarget

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203

(2014) Min Zhou et al.   CELLULAR IMMUNOLOGY

The Role of Neuroendocrine Cells in Prostate Cancer: A Comprehensive Review of Current Literature and Subsequent Rationale to Broaden and Integrate Current Treatment Modalities

(2014) F. Lugnani et al.   CURRENT MEDICINAL CHEMISTRY

A Systemic Approach to Cancer Treatment: Tumor Cell Reprogramming Focused on Endocrine-Related Cancers

(2014) P.M. Biava et al.   CURRENT MEDICINAL CHEMISTRY

miR-200–containing extracellular vesicles promote breast cancer cell metastasis

(2014) Minh T.N. Le et al.   JOURNAL OF CLINICAL INVESTIGATION

Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8+ T Cells: Mechanism of Immune Evasion

(2014) Marie Lundholm et al.   PLoS One

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

(2014) T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB

(2014) Amy Chow et al.   Scientific Reports

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

Functions and Therapeutic Roles of Exosomes in Cancer

(2014) Jacob A. Tickner et al.   Frontiers in Oncology

Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)

(2013) Theresa L. Whiteside   BIOCHEMICAL SOCIETY TRANSACTIONS

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

(2013) Asfar S. Azmi et al.   CANCER AND METASTASIS REVIEWS

Viral Infection Controlled by a Calcium-Dependent Lipid-Binding Module in ALIX

(2013) Christin Bissig et al.   DEVELOPMENTAL CELL

miR-142-3p Prevents Macrophage Differentiation during Cancer-Induced Myelopoiesis

(2013) Nada Sonda et al.   IMMUNITY

Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules

(2013) Anand Ramteke et al.   MOLECULAR CARCINOGENESIS

Exosomes derived from Rab27a-overexpressing tumor cells elicit efficient induction of antitumor immunity

(2013) WENHAI LI et al.   Molecular Medicine Reports

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

Exosomes and immune surveillance of neoplastic lesions: a review

(2012) H-G Zhang et al.   BIOTECHNIC & HISTOCHEMISTRY

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro

(2012) Annamaria Marton et al.   IMMUNOLOGY LETTERS

Exosomes: New players in cell–cell communication

(2012) Claudia Bang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Human umbilical cord wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro

(2012) Kalamegam Gauthaman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of ROCK Activity in Cancer

(2012) Marie Morgan-Fisher et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins Derived from a Panel of Prostate Cell Lines with Distinct AR Phenotypes

(2012) Elham Hosseini-Beheshti et al.   MOLECULAR & CELLULAR PROTEOMICS

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Leukemia cell to endothelial cell communication via exosomal miRNAs

(2012) T Umezu et al.   ONCOGENE

Recent advances on the role of tumor exosomes in immunosuppression and disease progression

(2012) Paola Filipazzi et al.   SEMINARS IN CANCER BIOLOGY

Microvesicles Derived from Human Bone Marrow Mesenchymal Stem Cells Inhibit Tumor Growth

(2012) Stefania Bruno et al.   STEM CELLS AND DEVELOPMENT

Oncogenic extracellular vesicles in brain tumor progression

(2012) Esterina D’Asti et al.   Frontiers in Physiology

Exosomes and Cancer: A Newly Described Pathway of Immune Suppression

(2011) H.-G. Zhang et al.   CLINICAL CANCER RESEARCH

Complete Response in 5 Out of 38 Patients with Advanced Hepatocellular Carcinoma Treated with Stem Cell Differentiation Stage Factors: Case Reports from a Single Centre

(2011) T. Livraghi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Zebrafish Stem Cell Differentiation Stage Factors Suppress Bcl-xL Release and Enhance 5-Fu-Mediated Apoptosis in Colon Cancer Cells

(2011) F. D'Anselmi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Analysis of exosome release and its prognostic value in human colorectal cancer

(2011) J. Silva et al.   GENES CHROMOSOMES & CANCER

Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis

(2011) Simona Taverna et al.   INTERNATIONAL JOURNAL OF CANCER

Protein Targeting to Exosomes/Microvesicles by Plasma Membrane Anchors

(2011) Beiyi Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

(2011) Cecilia Lässer et al.   Journal of Translational Medicine

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Galectin-3 (Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia

(2011) M. Yamamoto-Sugitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

(2010) H. Sheldon et al.   BLOOD

Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

(2010) I. Nazarenko et al.   CANCER RESEARCH

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Human Wharton’s Jelly Stem Cells Have Unique Transcriptome Profiles Compared to Human Embryonic Stem Cells and Other Mesenchymal Stem Cells

(2010) Chui-Yee Fong et al.   Stem Cell Reviews and Reports

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Naïve human umbilical cord matrix derived stem cells significantly attenuate growth of human breast cancer cells in vitro and in vivo

(2009) Rie Ayuzawa et al.   CANCER LETTERS

Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease

(2009) Dolores Di Vizio et al.   CANCER RESEARCH

Doxorubicin: The Good, the Bad and the Ugly Effect

(2009) Cristina Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paracrine induction of endothelium by tumor exosomes

(2009) Joshua L Hood et al.   LABORATORY INVESTIGATION

Exosomal Secretion of Cytoplasmic Prostate Cancer Xenograft-derived Proteins

(2009) Flip H. Jansen et al.   MOLECULAR & CELLULAR PROTEOMICS

Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer

(2008) Shengming Dai et al.   MOLECULAR THERAPY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE