Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB

TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence

(2013) Ilana Chefetz et al.   CELL CYCLE

The noninflammatory role of high mobility group box 1/toll-like receptor 2 axis in the self-renewal of mammary cancer stem cells

(2013) Laura Conti et al.   FASEB JOURNAL

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

(2013) Niko P. Bretz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites

(2012) Jiehui Deng et al.   CANCER CELL

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice

(2010) Zhipeng Meng et al.   HEPATOLOGY

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation

(2009) Diana C. Hargreaves et al.   CELL

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Role of macrophages in tumour progression

(2009) K.S. Siveen et al.   IMMUNOLOGY LETTERS

Gene Expression Analysis of Macrophages That Facilitate Tumor Invasion Supports a Role for Wnt-Signaling in Mediating Their Activity in Primary Mammary Tumors

(2009) L. S. Ojalvo et al.   JOURNAL OF IMMUNOLOGY

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles

(2009) Alex Yuan et al.   PLoS One

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

(2009) K. Al-Nedawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer related inflammation: The macrophage connection

(2008) Antonio Sica et al.   CANCER LETTERS

TLR2 – promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity

(2008) Ulrich Zähringer et al.   IMMUNOBIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY