New Insights Into the Cancer–Microbiome–Immune Axis: Decrypting a Decade of Discoveries

Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials

(2020) M. Chalabi et al.   ANNALS OF ONCOLOGY

Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents

(2020) Jens Walter et al.   CELL

Therapeutics Targeting the Gut Microbiome: Rigorous Pipelines for Drug Development

(2020) Kate A. Markey et al.   Cell Host & Microbe

Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice

(2020) Giuseppina D'Alessandro et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling

(2020) Yaoyao Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

(2020) Cayetano Pleguezuelos-Manzano et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis

(2020) Wenting Zhang et al.   Frontiers in Immunology

MAIT Cells Come to the Rescue in Cancer Immunotherapy?

(2020) Zuzanna Lukasik et al.   Cancers

Biostimulating Gut Microbiome with Bilberry Anthocyanin Combo to Enhance Anti-PD-L1 Efficiency against Murine Colon Cancer

(2020) Xuerun Liu et al.   Microorganisms

439 CIGARETTE SMOKE EXPOSURE PROMOTES CANCER PROGRESSION THROUGH GUT MICROBIAL DYSBIOSIS

(2020) Prateek Sharma et al.   GASTROENTEROLOGY

Association of antibiotic exposure with survival and toxicity in patients with melanoma receiving immunotherapy

(2020) Jahan J Mohiuddin et al.   JNCI-Journal of the National Cancer Institute

Microbiome analyses of blood and tissues suggest cancer diagnostic approach

(2020) Gregory D. Poore et al.   NATURE

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

(2020) Maria Paula Roberti et al.   NATURE MEDICINE

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

(2020) Deborah Nejman et al.   SCIENCE

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

(2020) Clélia Coutzac et al.   Nature Communications

Gut Microbiota Modulate CD8 T Cell Responses to Influence Colitis-Associated Tumorigenesis

(2020) Amy I. Yu et al.   Cell Reports

Gut Microbiome Influences the Efficacy of PD-1 Antibody Immunotherapy on MSS-Type Colorectal Cancer via Metabolic Pathway

(2020) Xinjian Xu et al.   Frontiers in Microbiology

Survival of Patients Treated with Antibiotics and Immunotherapy for Cancer: A Systematic Review and Meta-Analysis

(2020) Fausto Petrelli et al.   Journal of Clinical Medicine

Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity

(2020) Rafael Ribeiro Almeida et al.   BRITISH JOURNAL OF CANCER

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

(2020) Yuanyuan Zhang et al.   Cellular & Molecular Immunology

Concomitant Antibiotic Use and Survival in Urothelial Carcinoma Treated with Atezolizumab

(2020) Ashley M. Hopkins et al.   EUROPEAN UROLOGY

Mucosal or systemic microbiota exposures shape the B cell repertoire

(2020) Hai Li et al.   NATURE

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

(2020) Eliran Kadosh et al.   NATURE

Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy

(2020) Lukas F. Mager et al.   SCIENCE

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

(2020) Lishay Parhi et al.   Nature Communications

Bacteriome and mycobiome and bacteriome-mycobiome interactions in head and neck squamous cell carcinoma

(2020) Elizabeth Shay et al.   Oncotarget

Taxonomic diversity of sputum microbiome in lung cancer patients and its relationship with chromosomal aberrations in blood lymphocytes

(2020) V. G. Druzhinin et al.   Scientific Reports

Symphony in chaos: Immune orchestra during pancreatic cancer progression

(2020) Prateek Sharma et al.   EBioMedicine

Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma

(2020) Yelena Lapidot et al.   mSystems

Association of Short-Chain Fatty Acids in the Gut Microbiome With Clinical Response to Treatment With Nivolumab or Pembrolizumab in Patients With Solid Cancer Tumors

(2020) Motoo Nomura et al.   JAMA Network Open

Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection

(2020) Braedon McDonald et al.   Cell Host & Microbe

Stool Microbiome Profiling of Patients with Metastatic Renal Cell Carcinoma Receiving Anti–PD-1 Immune Checkpoint Inhibitors

(2020) Nicholas J. Salgia et al.   EUROPEAN UROLOGY

Modulation of the Gut Microbiota Alters the Tumour-Suppressive Efficacy of Tim-3 Pathway Blockade in a Bacterial Species- and Host Factor-Dependent Manner

(2020) Bokyoung Lee et al.   Microorganisms

Fecal Microbiota Transplantation is Superior to Fidaxomicin for Treatment of Recurrent Clostridium difficile Infection

(2019) Christian Lodberg Hvas et al.   GASTROENTEROLOGY

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

(2019) Vasiliki Koliaraki et al.   Cell Reports

The IL-1/IL-1 receptor axis and tumor cell released inflammasome adaptor ASC are key regulators of TSLP secretion by cancer associated fibroblasts in pancreatic cancer

(2019) Emanuela Brunetto et al.   Journal for ImmunoTherapy of Cancer

Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development

(2019) Jawara Allen et al.   Genome Medicine

The human gut bacterial genotoxin colibactin alkylates DNA

(2019) Matthew R. Wilson et al.   SCIENCE

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

(2019) Takeshi Tanoue et al.   NATURE

Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer

(2019) Rogier Aäron Gaiser et al.   GUT

The role of the microbiome in immunologic development and its implication for pancreatic cancer immunotherapy

(2019) Vrishketan Sethi et al.   GASTROENTEROLOGY

Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer

(2019) Rui Li et al.   CELL DEATH AND DIFFERENTIATION

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

(2019) Chengcheng Jin et al.   CELL

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment

(2019) Ji Lv et al.   Cell Death & Disease

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice

(2019) Yan Li et al.   Nature Communications

Exploring the emerging role of the microbiome in cancer immunotherapy

(2019) Jessica Fessler et al.   Journal for ImmunoTherapy of Cancer

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

(2019) Annabell Bachem et al.   IMMUNITY

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Smoking and microbiome in oral, airway, gut and some systemic diseases

(2019) Chunrong Huang et al.   Journal of Translational Medicine

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

(2019) Sreyan Chowdhury et al.   NATURE MEDICINE

Circulating Microbiota-Based Metagenomic Signature for Detection of Hepatocellular Carcinoma

(2019) Eun Ju Cho et al.   Scientific Reports

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

(2019) Selena Vigano et al.   Frontiers in Immunology

Role of antibiotic use, plasma citrulline and blood microbiome in advanced non-small cell lung cancer patients treated with nivolumab

(2019) Julia Ouaknine Krief et al.   Journal for ImmunoTherapy of Cancer

Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma

(2019) Yi Zheng et al.   Journal for ImmunoTherapy of Cancer

Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy

(2019) Di-Wei Zheng et al.   Nature Biomedical Engineering

Induction of CD8 T cell cytotoxicity by fecal bacteria from healthy individuals and colorectal cancer patients

(2019) Yanli Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

(2019) Erick Riquelme et al.   CELL

Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy

(2019) Tongyan Liu et al.   Journal of Hematology & Oncology

Tumor neoantigens: from basic research to clinical applications

(2019) Tao Jiang et al.   Journal of Hematology & Oncology

Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer

(2019) David J. Pinato et al.   JAMA Oncology

The effect of antibiotics on the clinical outcomes of patients with solid cancers undergoing immune checkpoint inhibitor treatment: a retrospective study

(2019) Hyunho Kim et al.   BMC CANCER

Development of a colorectal cancer diagnostic model and dietary risk assessment through gut microbiome analysis

(2019) Jinho Yang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Immunity to commensal papillomaviruses protects against skin cancer

(2019) John D. Strickley et al.   NATURE

The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL

(2019) Berk Aykut et al.   NATURE

Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures

(2019) Iradj Sobhani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Author Correction: Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

(2019) Marta Reyman et al.   Nature Communications

NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis

(2019) Nour Ershaid et al.   Nature Communications

Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer

(2019) Lawrence Fong et al.   Cancer Discovery

Depletion of Foxp3 + regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome

(2019) Jan Kehrmann et al.   IMMUNOLOGY

Host- and Microbiota-Derived Extracellular Vesicles, Immune Function, and Disease Development

(2019) Laurence Macia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

(2019) Mireia Uribe-Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Phylogenomics — principles, opportunities and pitfalls of big‐data phylogenetics

(2019) Andrew D. Young et al.   SYSTEMATIC ENTOMOLOGY

Role of the intestinal microbiome in colorectal cancer surgery outcomes

(2019) Lelde Lauka et al.   World Journal of Surgical Oncology

Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer

(2018) L Derosa et al.   ANNALS OF ONCOLOGY

Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness

(2018) Edit Mikó et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Th9 Cells Represent a Unique Subset of CD4 + T Cells Endowed with the Ability to Eradicate Advanced Tumors

(2018) Yong Lu et al.   CANCER CELL

Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models

(2018) Ryan M Thomas et al.   CARCINOGENESIS

Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response

(2018) Vrishketan Sethi et al.   GASTROENTEROLOGY

Gut microbiota modulate T cell trafficking into human colorectal cancer

(2018) Eleonora Cremonesi et al.   GUT

Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape

(2018) Max D. Wellenstein et al.   IMMUNITY

Current understanding of the human microbiome

(2018) Jack A Gilbert et al.   NATURE MEDICINE

Extracellular vesicles in cancer — implications for future improvements in cancer care

(2018) Rong Xu et al.   Nature Reviews Clinical Oncology

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

(2018) Christine M. Dejea et al.   SCIENCE

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

CAR T cell immunotherapy for human cancer

(2018) Carl H. June et al.   SCIENCE

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

The revival of CpG oligonucleotide-based cancer immunotherapies

(2018) Tomasz Adamus et al.   Wspolczesna Onkologia-Contemporary Oncology

Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy

(2018) Jonathan F. Anker et al.   Nature Communications

The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression

(2018) Smruti Pushalkar et al.   Cancer Discovery

Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

(2018) Paula Díaz et al.   Frontiers in Microbiology

Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma

(2018) Zhigang Ren et al.   GUT

The use of faecal microbiota transplant as treatment for recurrent or refractoryClostridium difficileinfection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines

(2018) Benjamin H Mullish et al.   GUT

Cesarean Delivery May Affect the Early Biodiversity of Intestinal Bacteria

(2018) Giacomo Biasucci et al.   JOURNAL OF NUTRITION

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Regional variation limits applications of healthy gut microbiome reference ranges and disease models

(2018) Yan He et al.   NATURE MEDICINE

Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

(2018) Spencer C. Wei et al.   Cancer Discovery

Modulation of Pulmonary Microbiota by Antibiotic or Probiotic Aerosol Therapy: A Strategy to Promote Immunosurveillance against Lung Metastases

(2018) Valentino Le Noci et al.   Cell Reports

Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

(2018) Tsuyoshi Hamada et al.   Cancer Immunology Research

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

(2018) Vishal Singh et al.   CELL

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

(2018) Rodabe N. Amaria et al.   NATURE MEDICINE

Diagnostic Potential and Interactive Dynamics of the Colorectal Cancer Virome

(2018) Geoffrey D. Hannigan et al.   mBio

Long-term use of antibiotics and risk of colorectal adenoma

(2017) Yin Cao et al.   GUT

Secondary bile acid-induced dysbiosis promotes intestinal carcinogenesis

(2017) Hailong Cao et al.   INTERNATIONAL JOURNAL OF CANCER

The inhibitory impacts of Lactobacillus rhamnosus GG-derived extracellular vesicles on the growth of hepatic cancer cells

(2017) Elham Behzadi et al.   MICROBIAL PATHOGENESIS

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

(2017) Vinod P. Balachandran et al.   NATURE

Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells

(2017) Madhumathi Thirunavukkarasan et al.   PLoS One

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma

(2017) Hye Eun Park et al.   VIRCHOWS ARCHIV

Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE 2 -Mediated Suppression of Antitumor Immunity

(2017) Tze Mun Loo et al.   Cancer Discovery

Bacteriome and mycobiome associations in oral tongue cancer

(2017) Pranab K. Mukherjee et al.   Oncotarget

Natural Killer T Cells in Cancer Immunotherapy

(2017) Shiny Nair et al.   Frontiers in Immunology

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

(2017) Arthur E. Frankel et al.   NEOPLASIA

Distinct gut microbiome patterns associate with consensus molecular subtypes of colorectal cancer

(2017) Rachel V. Purcell et al.   Scientific Reports

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

(2017) Annelies Geirnaert et al.   Scientific Reports

Microbiome and Anticancer Immunosurveillance

(2016) Laurence Zitvogel et al.   CELL

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

(2016) Romain Daillère et al.   IMMUNITY

Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity

(2016) Andrew Hollands et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

Functional Redundancy-Induced Stability of Gut Microbiota Subjected to Disturbance

(2016) Andrés Moya et al.   TRENDS IN MICROBIOLOGY

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

(2016) Krista Dubin et al.   Nature Communications

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype

(2016) Leopoldo N. Segal et al.   Nature Microbiology

New horizons in tumor microenvironment biology: challenges and opportunities

(2015) Fei Chen et al.   BMC Medicine

Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation

(2015) Melanie R. Rutkowski et al.   CANCER CELL

Increased tumor infiltration by mucosal-associated invariant T cells correlates with poor survival in colorectal cancer patients

(2015) Luciane Zabijak et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Inhibition of squamous cancer growth in a mouse model by Staphylococcal enterotoxin B-triggered Th9 cell expansion

(2015) Bei-Ping Miao et al.   Cellular & Molecular Immunology

Influence of high-fat diet on gut microbiota

(2015) E. Angela Murphy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-κB

(2015) J.N. Rashida Gnanaprakasam et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-γ

(2015) Patrik Sundström et al.   JOURNAL OF IMMUNOLOGY

Neutrophil ageing is regulated by the microbiome

(2015) Dachuan Zhang et al.   NATURE

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Gut microbiome development along the colorectal adenoma–carcinoma sequence

(2015) Qiang Feng et al.   Nature Communications

Dysbiosis of Fungal Microbiota in the Intestinal Mucosa of Patients with Colorectal Adenomas

(2015) Chunguang Luan et al.   Scientific Reports

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade

(2015) D. M. Woods et al.   Cancer Immunology Research

Microbiota Modulate Tumoral Immune Surveillance in Lung through a   T17 Immune Cell-Dependent Mechanism

(2014) M. Cheng et al.   CANCER RESEARCH

The biology of bacterial peptidoglycans and their impact on host immunity and physiology

(2014) Richard Wheeler et al.   CELLULAR MICROBIOLOGY

Potential of fecal microbiota for early-stage detection of colorectal cancer

(2014) G. Zeller et al.   Molecular Systems Biology

High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity

(2014) Manon D. Schulz et al.   NATURE

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

(2014) Eva S Gollwitzer et al.   NATURE MEDICINE

Cesarean Section and Chronic Immune Disorders

(2014) A. Sevelsted et al.   PEDIATRICS

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viruses and the Microbiota

(2014) Christopher M. Robinson et al.   Annual Review of Virology

Role of Toll-Like Receptors in Immune Activation and Tolerance in the Liver

(2014) Nobuhiro Nakamoto et al.   Frontiers in Immunology

Intestinal Bacteria Modify Lymphoma Incidence and Latency by Affecting Systemic Inflammatory State, Oxidative Stress, and Leukocyte Genotoxicity

(2013) M. L. Yamamoto et al.   CANCER RESEARCH

Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer

(2013) L Bracci et al.   CELL DEATH AND DIFFERENTIATION

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Altered profile of human gut microbiome is associated with cirrhosis and its complications

(2013) Jasmohan S. Bajaj et al.   JOURNAL OF HEPATOLOGY

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Gut Bacteria Drive Kupffer Cell Expansion via MAMP-Mediated ICAM-1 Induction on Sinusoidal Endothelium and Influence Preservation-Reperfusion Injury after Orthotopic Liver Transplantation

(2012) Natasha Corbitt et al.   AMERICAN JOURNAL OF PATHOLOGY

Probiotics prevent necrotizing enterocolitis by modulating enterocyte genes that regulate innate immune-mediated inflammation

(2012) Kriston Ganguli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

Infant antibiotic exposures and early-life body mass

(2012) L Trasande et al.   INTERNATIONAL JOURNAL OF OBESITY

Role of theHelicobacter pylori-Induced inflammatory response in the development of gastric cancer

(2012) Acacia Lamb et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study

(2012) Roberto Flores et al.   Journal of Translational Medicine

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

(2012) Sergei I. Grivennikov et al.   NATURE

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation

(2012) Peera Hemarajata et al.   Therapeutic Advances in Gastroenterology

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

(2011) Tina Herbst et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Emerging Roles of Anacardic Acid and Its Derivatives: A Pharmacological Overview

(2011) Mahadevappa Hemshekhar et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Association Between the Use of Antibiotics in the First Year of Life and Pediatric Inflammatory Bowel Disease

(2010) Souradet Y Shaw et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma

(2010) Mark P. Chao et al.   CELL

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

Fusobacterium nucleatum Outer Membrane Proteins Fap2 and RadD Induce Cell Death in Human Lymphocytes

(2010) C. W. Kaplan et al.   INFECTION AND IMMUNITY

Breast-feeding in relation to asthma, lung function, and sensitization in young schoolchildren

(2010) Inger Kull et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens

(2009) J G Fox et al.   GUT

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Urothelial dysplasia and inflammation induced by Schistosoma haematobium total antigen instillation in mice normal urothelium

(2009) Mónica C. Botelho et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

The complete genome of an individual by massively parallel DNA sequencing

(2008) David A. Wheeler et al.   NATURE

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

The influence of sex, handedness, and washing on the diversity of hand surface bacteria

(2008) N. Fierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA