Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity

Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer cells by the regulation of p53, MAPK and NFκβ pathways

(2016) M. Harsha Raj et al.   APOPTOSIS

Lysophospholipid receptors in drug discovery

(2015) Yasuyuki Kihara et al.   EXPERIMENTAL CELL RESEARCH

Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide

(2015) Ross Corriden et al.   Nature Communications

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Efficient synthesis of anacardic acid analogues and their antibacterial activities

(2013) Sreeman K. Mamidyala et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antibacterial and anti-inflammatory effects of Syzygium jambos L. (Alston) and isolated compounds on acne vulgaris

(2013) Richa Sharma et al.   BMC Complementary and Alternative Medicine

Induction of the Endoplasmic Reticulum Stress and Autophagy in Human Lung Carcinoma A549 Cells by Anacardic Acid

(2013) Yeong-Ae Seong et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Pyocyanin-Enhanced Neutrophil Extracellular Trap Formation Requires the NADPH Oxidase

(2013) Balázs Rada et al.   PLoS One

SUMO1 Negatively Regulates Reactive Oxygen Species Production From NADPH Oxidases

(2011) Deepesh Pandey et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Emerging Roles of Anacardic Acid and Its Derivatives: A Pharmacological Overview

(2011) Mahadevappa Hemshekhar et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists

(2011) Miguel Guerrero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Sphingosine-1-phosphate Lyase Deficiency Produces a Pro-inflammatory Response While Impairing Neutrophil Trafficking

(2010) Maria L. Allende et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G protein-coupled receptors: novel targets for drug discovery in cancer

(2010) Rosamaria Lappano et al.   NATURE REVIEWS DRUG DISCOVERY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps

(2009) Maren von Köckritz-Blickwede et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor- B-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor- B  kinase, leading to potentiation of apoptosis

(2008) B. Sung et al.   BLOOD

ETosis: A Novel Cell Death Pathway

(2008) F. Wartha et al.   Science Signaling