Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

Increased risk of stroke among patients with Crohn’s disease: a population-based matched cohort study

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Endothelial CD36 Contributes to Postischemic Brain Injury by Promoting Neutrophil Activation via CSF3

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(2015) Antoine Louveau et al.   NATURE

Functional Role of Regulatory Lymphocytes in Stroke: Facts and Controversies

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Neutrophil recruitment to the brain in mouse and human ischemic stroke

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(2014) Charlie G. Buffie et al.   NATURE

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The gut microbiota influences blood-brain barrier permeability in mice

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Functional development of γδ T cells

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Progranulin Deficiency Promotes Post-Ischemic Blood-Brain Barrier Disruption

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Transcranial amelioration of inflammation and cell death after brain injury

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PRO: Regulatory T Cells Are Protective in Ischemic Stroke

(2013) X. Hu et al.   STROKE

CON: Regulatory T Cells Are Protective in Ischemic Stroke

(2013) C. Kleinschnitz et al.   STROKE

Adoptive regulatory T-cell therapy protects against cerebral ischemia

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Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

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Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

(2012) C. Kleinschnitz et al.   BLOOD

Immunoregulation by the gut microbiota

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Regulatory T Cells Accumulate and Proliferate in the Ischemic Hemisphere for up to 30 Days after MCAO

(2012) Tobias Stubbe et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice

(2012) Carles Ubeda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

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Animal Research: Reporting in vivo Experiments—The ARRIVE Guidelines

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Stroke and the immune system: from pathophysiology to new therapeutic strategies

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The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Intestinal CD103+ dendritic cells: master regulators of tolerance?

(2011) Charlotte L. Scott et al.   TRENDS IN IMMUNOLOGY

Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice

(2011) Andréa M. Caricilli et al.   PLOS BIOLOGY

Grafting the Olfactory Epithelium to the Olfactory Bulb

(2010) Sayaka Yagi et al.   American Journal of Rhinology & Allergy

Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability

(2010) Christian Erbel et al.   BASIC RESEARCH IN CARDIOLOGY

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

(2010) C. Kleinschnitz et al.   BLOOD

T Regulatory Cells Maintain Intestinal Homeostasis by Suppressing γδ T Cells

(2010) Sung-Gyoo Park et al.   IMMUNITY

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities

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Use of KikGR a photoconvertible green-to-red fluorescent protein for cell labeling and lineage analysis in ES cells and mouse embryos

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Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Interleukin-23/Th17 pathways and inflammatory bowel disease

(2009) Clara Abraham et al.   INFLAMMATORY BOWEL DISEASES

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Neutrophil elastase and neurovascular injury following focal stroke and reperfusion

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CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

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Regulatory T Cells: Mechanisms of Differentiation and Function

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