Potential of extracellular vesicles in the Parkinson's disease – Pathological mediators and biomarkers
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Title
Potential of extracellular vesicles in the Parkinson's disease – Pathological mediators and biomarkers
Authors
Keywords
Extracellular vesicles, Biomarker, Parkinson's disease, α-synuclein, Omics, PD-Related genes
Journal
NEUROCHEMISTRY INTERNATIONAL
Volume 144, Issue -, Pages 104974
Publisher
Elsevier BV
Online
2021-01-22
DOI
10.1016/j.neuint.2021.104974
References
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Note: Only part of the references are listed.- A longitudinal study on α‐synuclein in plasma neuronal exosomes as a biomarker for Parkinson’s disease development and progression
- (2020) M. Niu et al. EUROPEAN JOURNAL OF NEUROLOGY
- Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism
- (2020) Cheng Jiang et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Plasma exosomal prion protein levels are correlated with cognitive decline in PD patients
- (2020) Bing Leng et al. NEUROSCIENCE LETTERS
- Long Noncoding RNA POU3F3 and α-Synuclein in Plasma L1CAM Exosomes Combined with β-Glucocerebrosidase Activity: Potential Predictors of Parkinson’s Disease
- (2020) Jing Zou et al. Neurotherapeutics
- Molecular and Cellular Impact of Inflammatory Extracellular Vesicles (EVs) Derived from M1 and M2 Macrophages on Neural Action Potentials
- (2020) Sarah Vakili et al. Brain Sciences
- Paper-based ITP technology: An application to specific cancer-derived exosome detection and analysis
- (2020) Shuang Guo et al. BIOSENSORS & BIOELECTRONICS
- Extracellular Vesicles Secreted by Astroglial Cells Transport Apolipoprotein D to Neurons and Mediate Neuronal Survival Upon Oxidative Stress
- (2019) Raquel Pascua-Maestro et al. Frontiers in Cellular Neuroscience
- Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson’s Disease
- (2019) Zhen-Hua Zhao et al. Frontiers in Aging Neuroscience
- Microglia as modulators of exosomal alpha-synuclein transmission
- (2019) Yun Xia et al. Cell Death & Disease
- New windows into the brain: Central nervous system-derived extracellular vesicles in blood
- (2019) Min Shi et al. PROGRESS IN NEUROBIOLOGY
- Exosomes
- (2019) D. Michiel Pegtel et al. Annual Review of Biochemistry
- The multiple roles of exosomes in Parkinson's disease: an overview
- (2019) Chiara Porro et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Extracellular microvesicles-derived from microglia treated with unaggregated α-synuclein attenuate mitochondrial fission and toxicity-induced by Parkinsonian toxin MPP+
- (2019) Na Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Neuronal exosomes in saliva of Parkinson's disease patients: A pilot study
- (2019) Komal Rani et al. PARKINSONISM & RELATED DISORDERS
- Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity
- (2019) Charisse N. Winston et al. Frontiers in Neuroscience
- Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21–5p and miR-331–5p
- (2019) Heng-Sheng Zhang et al. LIFE SCIENCES
- Real-time imaging of multivesicular body–plasma membrane fusion to quantify exosome release from single cells
- (2019) Maarten P. Bebelman et al. Nature Protocols
- miR-19b-3p inhibits breast cancer cell proliferation and reverses saracatinib-resistance by regulating PI3K/Akt pathway
- (2018) Juan Jin et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Inhibition of microRNA-505 suppressed MPP+-induced cytotoxicity of SHSY5Y cells in an in vitro Parkinson's disease model
- (2018) Jianzhong Zhu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Shedding light on the cell biology of extracellular vesicles
- (2018) Guillaume van Niel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study
- (2018) Hua Wang et al. NEUROBIOLOGY OF DISEASE
- Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy
- (2018) Natascha Fussi et al. Cell Death & Disease
- Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's Disease
- (2018) Yuki Kitamura et al. NEUROSCIENCE
- Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells
- (2018) Gabriel Gustafsson et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases
- (2018) Takuma Ohmichi et al. PARKINSONISM & RELATED DISORDERS
- The Methods of Choice for Extracellular Vesicles (EVs) Characterization
- (2017) Rafal Szatanek et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury
- (2017) Alok Kumar et al. Journal of Neuroinflammation
- Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury
- (2017) Rachna Manek et al. MOLECULAR NEUROBIOLOGY
- High-purity capture and release of circulating exosomes using an exosome-specific dual-patterned immunofiltration (ExoDIF) device
- (2017) Yoon-Tae Kang et al. Nanoscale
- MicroRNA biomarkers of Parkinson’s disease in serum exosome-like microvesicles
- (2017) Xiang-Yang Cao et al. NEUROSCIENCE LETTERS
- Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes
- (2017) Maja Mustapic et al. Frontiers in Neuroscience
- Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers
- (2017) Shijie Wang et al. Acta Neuropathologica Communications
- Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
- (2017) Jennifer Ngolab et al. Acta Neuropathologica Communications
- CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease
- (2016) Min Shi et al. Alzheimers & Dementia
- Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices
- (2016) Jina Ko et al. ANALYST
- Schwann Cell Exosomes Mediate Neuron–Glia Communication and Enhance Axonal Regeneration
- (2016) Rodrigo Lopez-Leal et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Chromatography and its hyphenation to mass spectrometry for extracellular vesicle analysis
- (2016) Gabriella Pocsfalvi et al. JOURNAL OF CHROMATOGRAPHY A
- Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway
- (2016) Pingping Song et al. JOURNAL OF NEUROSCIENCE
- Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease
- (2016) Kyle B. Fraser et al. MOVEMENT DISORDERS
- Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019SLRRK2carriers
- (2016) Kyle B. Fraser et al. NEUROLOGY
- Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
- (2016) Joanna Kowal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extracellular Vesicles in Physiology, Pathology, and Therapy of the Immune and Central Nervous System, with Focus on Extracellular Vesicles Derived from Mesenchymal Stem Cells as Therapeutic Tools
- (2016) Sylwia Koniusz et al. Frontiers in Cellular Neuroscience
- Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
- (2015) Anne Stuendl et al. BRAIN
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Directional cell movement through tissues is controlled by exosome secretion
- (2015) Bong Hwan Sung et al. Nature Communications
- Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease
- (2015) YaXing Gui et al. Oncotarget
- Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia
- (2015) Insaf Bahrini et al. Scientific Reports
- Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease
- (2014) Min Shi et al. ACTA NEUROPATHOLOGICA
- Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
- (2014) Marina Colombo et al. Annual Review of Cell and Developmental Biology
- Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment
- (2014) Anne-Maria Poehler et al. Autophagy
- Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration
- (2014) Liang Ma et al. CELL RESEARCH
- Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes
- (2014) Stephanie M.Y. Kong et al. HUMAN MOLECULAR GENETICS
- LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity
- (2014) Patricia Gómez-Suaga et al. HUMAN MOLECULAR GENETICS
- ATP13A2/PARK9 Regulates Secretion of Exosomes and -Synuclein
- (2014) T. Tsunemi et al. JOURNAL OF NEUROSCIENCE
- Regulation of Postsynaptic Retrograde Signaling by Presynaptic Exosome Release
- (2013) Ceren Korkut et al. NEURON
- Exosomes of BV-2 cells induced by alpha-synuclein: Important mediator of neurodegeneration in PD
- (2013) Chongwang Chang et al. NEUROSCIENCE LETTERS
- Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma
- (2013) Hina Kalra et al. PROTEOMICS
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication
- (2013) Carsten Frühbeis et al. PLOS BIOLOGY
- RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis
- (2013) Sabrina M. Heman-Ackah et al. Frontiers in Molecular Neuroscience
- Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing
- (2013) Piroon Jenjaroenpun et al. PeerJ
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
- (2012) Sabrina M Lehmann et al. NATURE NEUROSCIENCE
- Activation of the unfolded protein response enhances motor recovery after spinal cord injury
- (2012) V Valenzuela et al. Cell Death & Disease
- Microglial microvesicle secretion and intercellular signaling
- (2012) Elena Turola Frontiers in Physiology
- Identification of blood microRNAs associated to Parkinsońs disease
- (2011) Regina Margis et al. JOURNAL OF BIOTECHNOLOGY
- Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
- (2011) D. Fitzner et al. JOURNAL OF CELL SCIENCE
- α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
- (2011) Brit Mollenhauer et al. LANCET NEUROLOGY
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease
- (2011) Ruenn Chai Lai et al. Regenerative Medicine
- Clinical progression in Parkinson disease and the neurobiology of axons
- (2010) Hsiao-Chun Cheng et al. ANNALS OF NEUROLOGY
- Cell-Produced -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
- (2010) E. Emmanouilidou et al. JOURNAL OF NEUROSCIENCE
- Microglia in the aging brain: relevance to neurodegeneration
- (2010) Xiao-Guang Luo et al. Molecular Neurodegeneration
- Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease
- (2010) Min Shi et al. NEUROSCIENCE LETTERS
- Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants
- (2010) Cintia Roodveldt et al. PLoS One
- let-7Overexpression Leads to an Increased Fraction of Cells in G2/M, Direct Down-regulation of Cdc34, and Stabilization of Wee1 Kinase in Primary Fibroblasts
- (2009) Aster Legesse-Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microfluidic isolation and transcriptome analysis of serum microvesicles
- (2009) Chihchen Chen et al. LAB ON A CHIP
- Differential DJ-1 gene expression in Parkinson's disease
- (2009) Ravindran Kumaran et al. NEUROBIOLOGY OF DISEASE
- Debris clearance by microglia: an essential link between degeneration and regeneration
- (2008) H. Neumann et al. BRAIN
- LRRK2 regulates synaptic vesicle endocytosis
- (2008) Narae Shin et al. EXPERIMENTAL CELL RESEARCH
- Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells
- (2008) Tereza Vogiatzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
- (2008) Shaji Theodore et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
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