Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices

Early Detection of Pancreatic Cancer: Why, who, and how to Screen

(2017) Jason Klapman et al.   Cancer Control

High-Throughput and Label-Free Single Nanoparticle Sizing Based on Time-Resolved On-Chip Microscopy

(2015) Euan McLeod et al.   ACS Nano

Acoustic Purification of Extracellular Microvesicles

(2015) Kyungheon Lee et al.   ACS Nano

Rapid inertial solution exchange for enrichment and flow cytometric detection of microvesicles

(2015) Jaideep S. Dudani et al.   Biomicrofluidics

Why have ovarian cancer mortality rates declined? Part III. Prospects for the future

(2015) Victoria Sopik et al.   GYNECOLOGIC ONCOLOGY

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

(2015) Huilin Shao et al.   Nature Communications

Label-Free Quantitative Detection of Tumor-Derived Exosomes through Surface Plasmon Resonance Imaging

(2014) Ling Zhu et al.   ANALYTICAL CHEMISTRY

Detecting Exosomes Specifically: A Multiplexed Device Based on Alternating Current Electrohydrodynamic Induced Nanoshearing

(2014) Ramanathan Vaidyanathan et al.   ANALYTICAL CHEMISTRY

Determination of Exosome Concentration in Solution Using Surface Plasmon Resonance Spectroscopy

(2014) Déborah L. M. Rupert et al.   ANALYTICAL CHEMISTRY

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer

(2014) Christoph Kahlert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bladder Cancer Exosomes Contain EDIL-3/Del1 and Facilitate Cancer Progression

(2014) Carla J. Beckham et al.   JOURNAL OF UROLOGY

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

(2014) D. A. Haber et al.   Cancer Discovery

Track-Etched Magnetic Micropores for Immunomagnetic Isolation of Pathogens

(2014) Melaku Muluneh et al.   Advanced Healthcare Materials

Magnetic Ligation Method for Quantitative Detection of MicroRNAs

(2014) Monty Liong et al.   Advanced Healthcare Materials

Dielectrophoretic Capture and Genetic Analysis of Single Neuroblastoma Tumor Cells

(2014) Erica L. Carpenter et al.   Frontiers in Oncology

Screening for Prostate Cancer: U.S. Preventive Services Task Force Recommendation Statement

(2013)   ANNALS OF INTERNAL MEDICINE

Real-time Liquid Biopsy in Cancer Patients: Fact or Fiction?

(2013) K. Pantel et al.   CANCER RESEARCH

Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs

(2013) B. Allard et al.   CLINICAL CANCER RESEARCH

Detection of Circulating Pancreas Epithelial Cells in Patients With Pancreatic Cystic Lesions

(2013) Andrew D. Rhim et al.   GASTROENTEROLOGY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Innovation in detection of microparticles and exosomes

(2013) E. van der Pol et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles

(2013) Zongxing Wang et al.   LAB ON A CHIP

Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells

(2013) Cesar M. Castro et al.   LAB ON A CHIP

Singular phase nano-optics in plasmonic metamaterials for label-free single-molecule detection

(2013) V. G. Kravets et al.   NATURE MATERIALS

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions

(2013) Jung Ok Park et al.   PROTEOMICS

Inertial Focusing for Tumor Antigen-Dependent and -Independent Sorting of Rare Circulating Tumor Cells

(2013) E. Ozkumur et al.   Science Translational Medicine

Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients

(2012) Cicek Gercel-Taylor et al.   ANALYTICAL BIOCHEMISTRY

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cells

(2012) Chin Y. Soo et al.   IMMUNOLOGY

Biomarker Utility of Circulating Tumor Cells in Metastatic Cutaneous Melanoma

(2012) Leila Khoja et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers

(2012) M. Lucrecia Alvarez et al.   KIDNEY INTERNATIONAL

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

(2012) Huilin Shao et al.   NATURE MEDICINE

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Targeting ALK in neuroblastoma—preclinical and clinical advancements

(2012) Erica L. Carpenter et al.   Nature Reviews Clinical Oncology

Circulating Tumor Cells: Getting More from Less

(2012) J. M. Lang et al.   Science Translational Medicine

Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector

(2012) D. Issadore et al.   Science Translational Medicine

Resistive Pulse Sensing of Analyte-Induced Multicomponent Rod Aggregation Using Tunable Pores

(2012) Mark Platt et al.   Small

Carbon Nanotube Microwell Array for Sensitive Electrochemiluminescent Detection of Cancer Biomarker Proteins

(2011) Naimish P. Sardesai et al.   ANALYTICAL CHEMISTRY

Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance

(2011) Monty Liong et al.   BIOCONJUGATE CHEMISTRY

Microvesicles: Messengers and mediators of tumor progression

(2011) Khalid Al-Nedawi et al.   CELL CYCLE

A filtration-based protocol to isolate human Plasma Membrane-derived Vesicles and exosomes from blood plasma

(2011) Ryan Grant et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Miniature magnetic resonance system for point-of-care diagnostics

(2011) David Issadore et al.   LAB ON A CHIP

Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array

(2011) Waheb Bishara et al.   LAB ON A CHIP

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

(2011) Deniz Pekin et al.   LAB ON A CHIP

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

(2011) Rebecca A. Dragovic et al.   Nanomedicine-Nanotechnology Biology and Medicine

Microfluidics-based diagnostics of infectious diseases in the developing world

(2011) Curtis D Chin et al.   NATURE MEDICINE

A high-throughput label-free nanoparticle analyser

(2011) Jean-Luc Fraikin et al.   Nature Nanotechnology

Quantification of protein interactions and solution transport using high-density GMR sensor arrays

(2011) Richard S. Gaster et al.   Nature Nanotechnology

HER2-Positive Circulating Tumor Cells in Breast Cancer

(2011) Michail Ignatiadis et al.   PLoS One

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

(2010) Nobuyoshi Kosaka et al.   CANCER SCIENCE

Flow cytometric analysis of circulating microparticles in plasma

(2010) Aaron F. Orozco et al.   CYTOMETRY PART A

Optical and non-optical methods for detection and characterization of microparticles and exosomes

(2010) E. VAN DER POL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Nanofluidic technology for biomolecule applications: a critical review

(2010) M. Napoli et al.   LAB ON A CHIP

Lensfree microscopy on a cellphone

(2010) Derek Tseng et al.   LAB ON A CHIP

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

(2009) J Nilsson et al.   BRITISH JOURNAL OF CANCER

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Microfluidic isolation and transcriptome analysis of serum microvesicles

(2009) Chihchen Chen et al.   LAB ON A CHIP

Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature

(2009) Suresh Mathivanan et al.   MOLECULAR & CELLULAR PROTEOMICS

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors

(2009) A F Gazdar   ONCOGENE

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Chip–NMR biosensor for detection and molecular analysis of cells

(2008) Hakho Lee et al.   NATURE MEDICINE