Organ‐on‐a‐Chip: A Preclinical Microfluidic Platform for the Progress of Nanomedicine

Organ-on-a-chip: recent breakthroughs and future prospects

(2020) Qirui Wu et al.   Biomedical Engineering Online

Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy

(2020) Quan Zhou et al.   BIOMATERIALS

Bidirectional Regulation of Singlet Oxygen Generation from Luminescent Gold Nanoparticles through Surface Manipulation

(2020) Lulu Liu et al.   Small

Safety Considerations of Cancer Nanomedicine—A Key Step toward Translation

(2020) Xiangsheng Liu et al.   Small

Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

(2019) Seyed Mohammadali Dadfar et al.   ADVANCED DRUG DELIVERY REVIEWS

Human blood vessel organoids as a model of diabetic vasculopathy

(2019) Reiner A. Wimmer et al.   NATURE

Development of Tungsten Oxide Nanoparticle Modified Carbon Fibre Cloth as Flexible pH Sensor

(2019) Mamun Jamal et al.   Scientific Reports

Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway

(2019) Richard J. Mills et al.   Cell Stem Cell

A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations

(2019) Pranita K. Kabadi et al.   Particle and Fibre Toxicology

Organoids of liver diseases: From bench to bedside

(2019) Li-Jun Wu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

3D Printing of Personalized Thick and Perfusable Cardiac Patches and Hearts

(2019) Nadav Noor et al.   Advanced Science

Colorectal tumor-on-a-chip system: A 3D tool for precision onco-nanomedicine

(2019) M. R. Carvalho et al.   Science Advances

AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model

(2019) Wenwen Liu et al.   Acta Biomaterialia

Evaluating Nanoparticles in Preclinical Research Using Microfluidic Systems

(2019) Derui Zhu et al.   Micromachines

Tetrafluoroethylene-Propylene Elastomer for Fabrication of Microfluidic Organs-on-Chips Resistant to Drug Absorption

(2019) Emi Sano et al.   Micromachines

Recent Trends of the Bio-Inspired Nanoparticles in Cancer Theranostics

(2019) Vijay Sagar Madamsetty et al.   Frontiers in Pharmacology

Vascularized cancer on a chip: The effect of perfusion on growth and drug delivery of tumor spheroid

(2019) Yuji Nashimoto et al.   BIOMATERIALS

Updates on the use of liposomes for active tumor targeting in cancer therapy

(2019) Wei Yan et al.   Nanomedicine

Drug delivery devices for retinal diseases

(2018) Hirokazu Kaji et al.   ADVANCED DRUG DELIVERY REVIEWS

Multifunctional 3D electrode platform for real-time in situ monitoring and stimulation of cardiac tissues

(2018) Ning Zhang et al.   BIOSENSORS & BIOELECTRONICS

Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development

(2018) Kacey Ronaldson-Bouchard et al.   Cell Stem Cell

Orthogonal Clickable Iron Oxide Nanoparticle Platform for Targeting, Imaging, and On-Demand Release

(2018) Noelia Guldris et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organ/body-on-a-chip based on microfluidic technology for drug discovery

(2018) Hiroshi Kimura et al.   Drug Metabolism and Pharmacokinetics

Liver ‘organ on a chip’

(2018) Colin H. Beckwitt et al.   EXPERIMENTAL CELL RESEARCH

Stimuli-responsive polymeric micelles for drug delivery and cancer therapy

(2018) Qing Zhou et al.   International Journal of Nanomedicine

Mesoporous silica nanoparticles in nanomedicine applications

(2018) Miguel Manzano et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Microsensor systems for cell metabolism – from 2D culture to organ-on-chip

(2018) Jochen Kieninger et al.   LAB ON A CHIP

Design and fabrication of a liver-on-a-chip platform for convenient, highly efficient, and safe in situ perfusion culture of 3D hepatic spheroids

(2018) Li-Dong Ma et al.   LAB ON A CHIP

Organoids

(2018) Natalie de Souza   NATURE METHODS

Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells

(2018) Plansky Hoang et al.   Nature Protocols

Advances in Carbon Nanotubes-Hydrogel Hybrids in Nanomedicine for Therapeutics

(2018) Arti Vashist et al.   Advanced Healthcare Materials

Deformation of Red Blood Cells, Air Bubbles, and Droplets in Microfluidic Devices: Flow Visualizations and Measurements

(2018) David Bento et al.   Micromachines

Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia and dual stimuli-responsive drug delivery

(2018) Raquel O. Rodrigues et al.   Materials Science & Engineering C-Materials for Biological Applications

Evaluating nanomedicine in microfluidics

(2018) Ziyi He et al.   NANOTECHNOLOGY

Multi-organ on a chip for personalized precision medicine

(2018) Vivekanandan Palaninathan et al.   MRS Communications

Nano based drug delivery systems: recent developments and future prospects

(2018) Jayanta Kumar Patra et al.   JOURNAL OF NANOBIOTECHNOLOGY

Tumor-Vasculature-on-a-Chip for Investigating Nanoparticle Extravasation and Tumor Accumulation

(2018) Hao-Fei Wang et al.   ACS Nano

Kidneys on Chips

(2018) Catherine K. Yeung et al.   Clinical Journal of the American Society of Nephrology

Kidney-on-a-chip: untapped opportunities

(2018) Nureddin Ashammakhi et al.   KIDNEY INTERNATIONAL

Organs-on-a-Chip Module: A Review from the Development and Applications Perspective

(2018) Juan Eduardo Sosa-Hernández et al.   Micromachines

Organs-on-chips: Progress, challenges, and future directions

(2017) Lucie A Low et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Nanomedicine applications in the treatment of breast cancer: current state of the art

(2017) Di Wu et al.   International Journal of Nanomedicine

Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment

(2017) Hsieh-Fu Tsai et al.   Journal of the Royal Society Interface

Organ-on-a-chip devices advance to market

(2017) Boyang Zhang et al.   LAB ON A CHIP

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

(2017) Yu Shrike Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies

(2017) Samad Ahadian et al.   Advanced Healthcare Materials

Nonmediated, Label-Free Based Detection of Cardiovascular Biomarker in a Biological Sample

(2017) JuKyung Lee et al.   Advanced Healthcare Materials

Synthesis, Functionalization, and Design of Magnetic Nanoparticles for Theranostic Applications

(2017) Jalal Mosayebi et al.   Advanced Healthcare Materials

Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro

(2017) Bryan A. Hassell et al.   Cell Reports

Pharmaceutical aspects of silver nanoparticles

(2017) Prateek Mathur et al.   Artificial Cells Nanomedicine and Biotechnology

Label-Free and Regenerative Electrochemical Microfluidic Biosensors for Continual Monitoring of Cell Secretomes

(2017) Su Ryon Shin et al.   Advanced Science

Medical devices on chips

(2017) Allan Guan et al.   Nature Biomedical Engineering

Microvasculature on a chip: study of the Endothelial Surface Layer and the flow structure of Red Blood Cells

(2017) Daria Tsvirkun et al.   Scientific Reports

Design and Construction of a Multi-Organ Microfluidic Chip Mimicking the in vivo Microenvironment of Lung Cancer Metastasis

(2016) Zhiyun Xu et al.   ACS Applied Materials & Interfaces

Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip

(2016) Yu Shrike Zhang et al.   BIOMATERIALS

In situ , dual-mode monitoring of organ-on-a-chip with smartphone-based fluorescence microscope

(2016) Soohee Cho et al.   BIOSENSORS & BIOELECTRONICS

Direct quantification of transendothelial electrical resistance in organs-on-chips

(2016) Marinke W. van der Helm et al.   BIOSENSORS & BIOELECTRONICS

Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature

(2016) Igho J. Onakpoya et al.   BMC Medicine

Gated mesoporous carbon nanoparticles as drug delivery system for stimuli-responsive controlled release

(2016) Xuan Huang et al.   CARBON

Haemocompatibility of iron oxide nanoparticles synthesized for theranostic applications: a high-sensitivity microfluidic tool

(2016) Raquel O. Rodrigues et al.   JOURNAL OF NANOPARTICLE RESEARCH

Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis

(2016) Onur Kilic et al.   LAB ON A CHIP

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Controlled Drug Release and Chemotherapy Response in a Novel Acoustofluidic 3D Tumor Platform

(2016) Ioannis K. Zervantonakis et al.   Small

Advances in Peptide Functionalization on Mesoporous Silica Nanoparticles for Controlled Drug Release

(2016) Jing-Jing Hu et al.   Small

Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening

(2016) Martijn J. Wilmer et al.   TRENDS IN BIOTECHNOLOGY

Light-Addressable Potentiometric Sensor as a Sensing Element in Plug-Based Microfluidic Devices

(2016) Ko-Ichiro Miyamoto et al.   Micromachines

Production and clinical development of nanoparticles for gene delivery

(2016) Jie Chen et al.   Molecular Therapy-Methods & Clinical Development

Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

(2016) Maierdanjiang Wufuer et al.   Scientific Reports

Retina-on-a-chip: a microfluidic platform for point access signaling studies

(2015) Kirsten H. Dodson et al.   BIOMEDICAL MICRODEVICES

A simple microfluidic device for the deformability assessment of blood cells in a continuous flow

(2015) Raquel O. Rodrigues et al.   BIOMEDICAL MICRODEVICES

Multifunctional nanoparticles: recent progress in cancer therapeutics

(2015) G. Seeta Rama Raju et al.   CHEMICAL COMMUNICATIONS

Smart Polymeric Nanoparticles for Cancer Gene Delivery

(2015) Guimei Lin et al.   MOLECULAR PHARMACEUTICS

Modeling nanoparticle wrapping or translocation in bilayer membranes

(2015) Emily M. Curtis et al.   Nanoscale

Smart nanosystems: Bio-inspired technologies that interact with the host environment

(2015) Ester J. Kwon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensional flow-based microfluidic device: deformability assessment of red blood cells in contact with tumor cells

(2014) Vera Faustino et al.   BioChip Journal

Organ-on-a-chip platforms for studying drug delivery systems

(2014) Nupura S. Bhise et al.   JOURNAL OF CONTROLLED RELEASE

Large-Scale Synthesis of Colloidal Fe3O4 Nanoparticles Exhibiting High Heating Efficiency in Magnetic Hyperthermia

(2014) Yury V. Kolen’ko et al.   Journal of Physical Chemistry C

A portable microfluidic device for the rapid diagnosis of cancer metastatic potential which is programmable for temperature and CO2

(2014) I. F. Yu et al.   LAB ON A CHIP

The present and future role of microfluidics in biomedical research

(2014) Eric K. Sackmann et al.   NATURE

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

A Bioartificial Renal Tubule Device Embedding Human Renal Stem/Progenitor Cells

(2014) Anna Giovanna Sciancalepore et al.   PLoS One

A polymeric device for controlled transscleral multi-drug delivery to the posterior segment of the eye

(2013) Nobuhiro Nagai et al.   Acta Biomaterialia

Multifunctional Nanoparticles for Drug Delivery and Molecular Imaging

(2013) Gang Bao et al.   Annual Review of Biomedical Engineering

A review of microfabrication and hydrogel engineering for micro-organs on chips

(2013) Marine Verhulsel et al.   BIOMATERIALS

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

(2013) Kyung-Jin Jang et al.   Integrative Biology

Microfluidic heart on a chip for higher throughput pharmacological studies

(2013) Ashutosh Agarwal et al.   LAB ON A CHIP

Hydrogel-coated microfluidic channels for cardiomyocyte culture

(2013) Nasim Annabi et al.   LAB ON A CHIP

Disease-on-a-chip: mimicry of tumor growth in mammary ducts

(2013) Pierre-Alexandre Vidi et al.   LAB ON A CHIP

Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels

(2013) Katawut Namdee et al.   LANGMUIR

Adhesive interaction of functionalized particles and endothelium in idealized microvascular networks

(2013) Giuseppina Lamberti et al.   MICROVASCULAR RESEARCH

Microfabrication of human organs-on-chips

(2013) Dongeun Huh et al.   Nature Protocols

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport

(2013) Alexandre Albanese et al.   Nature Communications

Multifunctional nanoparticle systems for combined chemoand photothermal cancer therapy

(2013) Hai Wang et al.   Frontiers of Materials Science

Microfluidic System for Facilitated Quantification of Nanoparticle Accumulation to Cells Under Laminar Flow

(2012) Jiro Kusunose et al.   ANNALS OF BIOMEDICAL ENGINEERING

A novel three-dimensional bone chip organ culture

(2012) Johannes Kuttenberger et al.   Clinical Oral Investigations

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Magnetic fluid hyperthermia: Focus on superparamagnetic iron oxide nanoparticles

(2011) Sophie Laurent et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Albumin handling by renal tubular epithelial cells in a microfluidic bioreactor

(2011) Nicholas Ferrell et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biomimetic tissues on a chip for drug discovery

(2011) Amir M. Ghaemmaghami et al.   DRUG DISCOVERY TODAY

Breast on-a-chip: mimicry of the channeling system of the breast for development of theranostics

(2011) Meggie M.G. Grafton et al.   Integrative Biology

Ferrite-based magnetic nanofluids used in hyperthermia applications

(2011) Ibrahim Sharifi et al.   JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy

(2010) Morteza Mahmoudi et al.   ADVANCED DRUG DELIVERY REVIEWS

Development of microfluidic devices for biomedical and clinical application

(2010) Abigail Webster et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

A physiologically realistic in vitro model of microvascular networks

(2009) Jenna M. Rosano et al.   BIOMEDICAL MICRODEVICES

Drug Development: From Concept to Marketing!

(2009) Nihad A.M. Tamimi et al.   NEPHRON CLINICAL PRACTICE