Smart nanosystems: Bio-inspired technologies that interact with the host environment

Intracellular Delivery System for Antibody–Peptide Drug Conjugates

(2015) Geoffrey Y Berguig et al.   MOLECULAR THERAPY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

A holistic approach to targeting disease with polymeric nanoparticles

(2015) Christopher J. Cheng et al.   NATURE REVIEWS DRUG DISCOVERY

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates

(2015) Danny Hung-Chieh Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A synthetic fibrin cross-linking polymer for modulating clot properties and inducing hemostasis

(2015) Leslie W. Chan et al.   Science Translational Medicine

Self-Titrating Anticoagulant Nanocomplexes That Restore Homeostatic Regulation of the Coagulation Cascade

(2014) Kevin Y. Lin et al.   ACS Nano

Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles

(2014) Erik C. Dreaden et al.   ACS Nano

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

(2014) Erik Procko et al.   CELL

Disease Detection by Ultrasensitive Quantification of Microdosed Synthetic Urinary Biomarkers

(2014) Andrew D. Warren et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Drug-induced amplification of nanoparticle targeting to tumors

(2014) Kevin Y. Lin et al.   Nano Today

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

(2014) Deju Ye et al.   Nature Chemistry

Managing diabetes with nanomedicine: challenges and opportunities

(2014) Omid Veiseh et al.   NATURE REVIEWS DRUG DISCOVERY

Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfluidics

(2014) A. D. Warren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of cooperation in cancer nanomedicine: towards systems nanotechnology

(2014) Sabine Hauert et al.   TRENDS IN BIOTECHNOLOGY

Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging

(2014) Molly A. Sowers et al.   Nature Communications

Host adaptation and transmission of influenza A viruses in mammals

(2014) Eefje JA Schrauwen et al.   Emerging Microbes & Infections

Nanoparticles That Sense Thrombin Activity As Synthetic Urinary Biomarkers of Thrombosis

(2013) Kevin Y. Lin et al.   ACS Nano

Injectable Nano-Network for Glucose-Mediated Insulin Delivery

(2013) Zhen Gu et al.   ACS Nano

Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery

(2013) Zhen Gu et al.   ACS Nano

Exploiting Oxidative Microenvironments in the Body as Triggers for Drug Delivery Systems

(2013) Shivanjali Joshi-Barr et al.   ANTIOXIDANTS & REDOX SIGNALING

In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides

(2013) Roy Weinstain et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety

(2013) L. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging

(2012) Jeffrey K. Mito et al.   CANCER

In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity

(2012) Emilia S. Olson et al.   Integrative Biology

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

(2012) Gabriel A Kwong et al.   NATURE BIOTECHNOLOGY

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

(2012) Vikash P. Chauhan et al.   Nature Nanotechnology

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Layer-by-Layer Nanoparticles with a pH-Sheddable Layer for in Vivo Targeting of Tumor Hypoxia

(2011) Zhiyong Poon et al.   ACS Nano

Nanoparticles that communicate in vivo to amplify tumour targeting

(2011) Geoffrey von Maltzahn et al.   NATURE MATERIALS

Self-Assembled pH-Sensitive Nanoparticles: A Platform for Oral Delivery of Protein Drugs

(2010) Kiran Sonaje et al.   ADVANCED FUNCTIONAL MATERIALS

Upconversion nanoparticles in biological labeling, imaging, and therapy

(2010) Feng Wang et al.   ANALYST

Targeted Nanoparticles That Deliver a Sustained, Specific Release of Paclitaxel to Irradiated Tumors

(2010) Ralph J. Passarella et al.   CANCER RESEARCH

Tumor-targeted delivery of liposome-encapsulated doxorubicin by use of a peptide that selectively binds to irradiated tumors

(2010) Amanda Lowery et al.   JOURNAL OF CONTROLLED RELEASE

Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

(2010) Neetu Singh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Optical and Multimodality Molecular Imaging

(2009) Farouc A. Jaffer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

(2009) Emilia S. Olson et al.   Integrative Biology

Intravenous Hemostat: Nanotechnology to Halt Bleeding

(2009) J. P. Bertram et al.   Science Translational Medicine

Porous silicon in drug delivery devices and materials☆

(2008) E ANGLIN et al.   ADVANCED DRUG DELIVERY REVIEWS

Noninvasive assessment of cancer response to therapy

(2008) Zhaozhong Han et al.   NATURE MEDICINE

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation

(2008) I-M. Yu et al.   SCIENCE

Protease-Triggered Unveiling of Bioactive Nanoparticles

(2008) Todd J. Harris et al.   Small