Design and fabrication of a liver-on-a-chip platform for convenient, highly efficient, and safe in situ perfusion culture of 3D hepatic spheroids

Constrained spheroids for prolonged hepatocyte culture

(2016) Wen Hao Tong et al.   BIOMATERIALS

Engineering a perfusable 3D human liver platform from iPS cells

(2016) Arnout Schepers et al.   LAB ON A CHIP

Magnetic force-assisted self-locking metallic bead array for fabrication of diverse concave microwell geometries

(2016) Gi-Hun Lee et al.   LAB ON A CHIP

Reproducible Construction of Surface Tension-Mediated Honeycomb Concave Microwell Arrays for Engineering of 3D Microtissues with Minimal Cell Loss

(2016) GeonHui Lee et al.   PLoS One

The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues

(2015) Kathryn Futrega et al.   BIOMATERIALS

Microfluidic 3D cell culture: from tools to tissue models

(2015) Vincent van Duinen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Structural and functional hepatocyte polarity and liver disease

(2015) Paul Gissen et al.   JOURNAL OF HEPATOLOGY

Spatiotemporal control of gene expression using microfluidics

(2014) Alexandre Benedetto et al.   LAB ON A CHIP

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

A three-dimensional co-culture of HepG2 spheroids and fibroblasts using double-layered fibrous scaffolds incorporated with hydrogel micropatterns

(2014) Hyue Won Lee et al.   RSC Advances

Design Criteria for Generating Physiologically Relevant In Vitro Models in Bioreactors

(2014) Giorgio Mattei et al.   Processes

Spheroid-based three-dimensional liver-on-a-chip to investigate hepatocyte–hepatic stellate cell interactions and flow effects

(2013) Seung-A Lee et al.   LAB ON A CHIP

3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies

(2013) Patrina Gunness et al.   TOXICOLOGICAL SCIENCES

Multilayered Heparin Hydrogel Microwells for Cultivation of Primary Hepatocytes

(2013) Jungmok You et al.   Advanced Healthcare Materials

Microfluidics for Manipulating Cells

(2012) Xuan Mu et al.   Small

In vitro models for liver toxicity testing

(2012) Valerie Y. Soldatow et al.   Toxicology Research

Concave microwell based size-controllable hepatosphere as a three-dimensional liver tissue model

(2011) Sau Fung Wong et al.   BIOMATERIALS

Meniscus induced self organization of multiple deep concave wells in a microchannel for embryoid bodies generation

(2011) Gi Seok Jeong et al.   LAB ON A CHIP

Functional clustering of pancreatic islet cells using concave microwell array

(2011) Jin Wook Hwang et al.   MACROMOLECULAR RESEARCH

Formation of Hepatocyte Spheroids with Structural Polarity and Functional Bile Canaliculi Using Nanopillar Sheets

(2010) Ryosuke Takahashi et al.   TISSUE ENGINEERING PART A

Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification

(2010) Danyel G. J. Jennen et al.   TOXICOLOGICAL SCIENCES

An easy to assemble microfluidic perfusion device with a magnetic clamp

(2009) Eugene Tkachenko et al.   LAB ON A CHIP

Fabrication of reversibly adhesive fluidic devices using magnetism

(2009) Marjan Rafat et al.   LAB ON A CHIP

Study of cellular behaviors on concave and convex microstructures fabricated from elastic PDMS membranes

(2009) Joong Yull Park et al.   LAB ON A CHIP

oxLDL facilitates flow-induced realignment of aortic endothelial cells

(2008) Gregory B. Kowalsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Which in vitro models could be best used to study hepatocyte polarity?

(2008) Catherine Decaens et al.   BIOLOGY OF THE CELL

Ice-lithographic fabrication of concave microwells and a microfluidic network

(2008) Joong Yull Park et al.   BIOMEDICAL MICRODEVICES

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

(2008) Ruei-Zhen Lin et al.   Biotechnology Journal