Biocatalysis – Key enabling tools from biocatalytic one-step and multi-step reactions to biocatalytic total synthesis

Use of real-time multiplex PCR, malaria rapid diagnostic test and microscopy to investigate the prevalence of Plasmodium species among febrile hospital patients in Sierra Leone

(2020) Tomasz A. Leski et al.   MALARIA JOURNAL

A combined experimental and modelling approach for the Weimberg pathway optimisation

(2020) Lu Shen et al.   Nature Communications

Engineering new catalytic activities in enzymes

(2020) Kai Chen et al.   Nature Catalysis

Selective Enzymatic Oxidation of Silanes to Silanols

(2020) Susanne Bähr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Building Bridges between Biotechnology and Chemistry – Oreste Ghisalba's Pioneering Activities, Publications and Programs

(2020) Roland Wohlgemuth   CHIMIA

Yeasts and molds in fermented food production: an ancient bioprocess

(2019) Marina Venturini Copetti   Current Opinion in Food Science

Reaction Engineering for the Industrial Implementation of Biocatalysis

(2019) John M. Woodley   TOPICS IN CATALYSIS

A Personal Reflection on the Chemistry‐Biology Interface

(2019) Dan S. Tawfik   ISRAEL JOURNAL OF CHEMISTRY

Non‐Oxidative Enzymatic (De)Carboxylation of (Hetero)Aromatics and Acrylic Acid Derivatives

(2019) Stefan E. Payer et al.   ADVANCED SYNTHESIS & CATALYSIS

Bioeconomy for sustainable development

(2019) Alfredo Aguilar et al.   Biotechnology Journal

The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts

(2019) Aoife M. Foley et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Isolation and Characterization of Live Yeast Cells from Ancient Vessels as a Tool in Bio-Archaeology

(2019) Tzemach Aouizerat et al.   mBio

Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion Intermediates

(2019) Chao Guo et al.   ACS Catalysis

Facile synthesis of D-xylulose-5-phosphate and L-xylulose-5-phosphate by xylulokinase-catalyzed phosphorylation

(2019) Norman Hardt et al.   BIOCATALYSIS AND BIOTRANSFORMATION

Efficient biocatalytic synthesis of D-tagatose 1,6-diphosphate by LacC-catalysed phosphorylation of D-tagatose 6-phosphate

(2019) Bernhard Schoenenberger et al.   BIOCATALYSIS AND BIOTRANSFORMATION

S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reactions

(2019) Cangsong Liao et al.   Nature Catalysis

Sustainable bioconversion of food waste into high-value products by immobilized enzymes to meet bio-economy challenges and opportunities – A review

(2019) Muhammad Bilal et al.   FOOD RESEARCH INTERNATIONAL

S -Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C -Alkylation

(2019) Iain J. W. McKean et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners

(2019) Jielin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways

(2019) Rémi Zallot et al.   BIOCHEMISTRY

Engineering transketolase to accept both unnatural donor and acceptor substrates and produce α‐hydroxyketones

(2019) Haoran Yu et al.   FEBS Journal

Fermentation for enhancing the bioconversion of glucoraphanin into sulforaphane and improve the functional attributes of broccoli puree

(2019) Yan Xue Cai et al.   Journal of Functional Foods

Glucose Measurement and Control in Patients with Type 1 or Type 2 Diabetes

(2019) Lutz Heinemann et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Industrial Enzymology: The Next Chapter

(2019) Michael V. Arbige et al.   TRENDS IN BIOTECHNOLOGY

Stereodivergent Evolution of Artificial Enzymes for the Michael Reaction

(2018) Xavier Garrabou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic Oxidation Reactions: A Chemist's Perspective

(2018) JiaJia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Basis for the Catalytic Mechanism of Ethylenediamine-N,N′-disuccinic Acid Lyase, a Carbon–Nitrogen Bond-Forming Enzyme with a Broad Substrate Scope

(2018) Harshwardhan Poddar et al.   BIOCHEMISTRY

Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate

(2018) Bernhard Schoenenberger et al.   Biotechnology Journal

Horizons of Systems Biocatalysis and Renaissance of Metabolite Synthesis

(2018) Roland Wohlgemuth   Biotechnology Journal

Biocatalytic Synthesis of Nitriles through Dehydration of Aldoximes: The Substrate Scope of Aldoxime Dehydratases

(2018) Tobias Betke et al.   CHEMBIOCHEM

The limits to biocatalysis: pushing the envelope

(2018) Roger A. Sheldon et al.   CHEMICAL COMMUNICATIONS

Biocatalytic reduction of activated C C-bonds and beyond: emerging trends

(2018) Christoph K Winkler et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

STRENDA DB: enabling the validation and sharing of enzyme kinetics data

(2018) Neil Swainston et al.   FEBS Journal

Enzymatic pulping of lignocellulosic biomass

(2018) Xuejiao Lin et al.   INDUSTRIAL CROPS AND PRODUCTS

A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology

(2018) Arturo Casini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational redesign of enzymes for regio- and enantioselective hydroamination

(2018) Ruifeng Li et al.   Nature Chemical Biology

Evolving biocatalysis to meet bioeconomy challenges and opportunities

(2018) Alessandro Pellis et al.   New Biotechnology

Bio-mediated generation of food flavors – Towards sustainable flavor production inspired by nature

(2018) Rachid Bel-Rhlid et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Multienzyme Cascade Reactions—Status and Recent Advances

(2018) Josef M. Sperl et al.   ACS Catalysis

Leloir Glycosyltransferases as Biocatalysts for Chemical Production

(2018) Bernd Nidetzky et al.   ACS Catalysis

Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate

(2018) Bernhard Schoenenberger et al.   Biotechnology Journal

Horizons of Systems Biocatalysis and Renaissance of Metabolite Synthesis

(2018) Roland Wohlgemuth   Biotechnology Journal

Biocatalytic Process for (−)-Ambrox Production Using Squalene Hopene Cyclase

(2018) Eric Eichhorn et al.   ADVANCED SYNTHESIS & CATALYSIS

Enzymatic Cascade Reactions in Biosynthesis

(2018) Christopher T. Walsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes

(2018) Rebecca M Demming et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovering novel hydrolases from hot environments

(2018) Roland Wohlgemuth et al.   BIOTECHNOLOGY ADVANCES

Complete reconstitution of the diverse pathways of gentamicin B biosynthesis

(2018) Yeon Hee Ban et al.   Nature Chemical Biology

Extending the application of biocatalysis to meet the challenges of drug development

(2018) Paul N. Devine et al.   Nature Reviews Chemistry

Transaminase biocatalysis: optimization and application

(2017) Fei Guo et al.   GREEN CHEMISTRY

The E factor 25 years on: the rise of green chemistry and sustainability

(2017) Roger A. Sheldon   GREEN CHEMISTRY

Developments in application of enzymes for textile processing

(2017) Amit Madhu et al.   JOURNAL OF CLEANER PRODUCTION

Structural and functional insights into asymmetric enzymatic dehydration of alkenols

(2017) Bettina M Nestl et al.   Nature Chemical Biology

A reductive aminase from Aspergillus oryzae

(2017) Godwin A. Aleku et al.   Nature Chemistry

Biocatalytic Phosphorylations of Metabolites: Past, Present, and Future

(2017) Roland Wohlgemuth et al.   TRENDS IN BIOTECHNOLOGY

Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

(2017) Iustina Slabu et al.   ACS Catalysis

Biocatalytic asymmetric Michael addition reaction of l-arginine to fumarate for the green synthesis of N-(([(4S)-4-amino-4-carboxy-butyl]amino)iminomethyl)-l-aspartic acid lithium salt (l-argininosuccinic acid lithium salt)

(2017) B. Schoenenberger et al.   RSC Advances

Application of an Acyl-CoA Ligase from Streptomyces aizunensis for Lactam Biosynthesis

(2017) Jingwei Zhang et al.   ACS Synthetic Biology

Conscious coupling: The challenges and opportunities of cascading enzymatic microreactors

(2017) Pia Gruber et al.   Biotechnology Journal

Approved Antiviral Drugs over the Past 50 Years

(2016) Erik De Clercq et al.   CLINICAL MICROBIOLOGY REVIEWS

Sulfation made easy: A new versatile donor for enzymatic sulfation by a bacterial arylsulfotransferase

(2016) Aloysius F. Hartog et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase

(2016) Ridao Chen et al.   Nature Chemical Biology

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

(2016) Jan-Ytzen van der Meer et al.   Nature Communications

Facile Enzymatic Synthesis of Phosphorylated Ketopentoses

(2016) Liuqing Wen et al.   ACS Catalysis

Systems biocatalysis: para-alkenylation of unprotected phenols

(2016) Eduardo Busto et al.   Catalysis Science & Technology

Catalyst: Synthetic Organic Chemistry as a Force for Good

(2016) K.C. Nicolaou   Chem

Highly efficient and scalable chemoenzymatic syntheses of (R)- and (S)-lactaldehydes

(2016) M. A. K. Vogel et al.   Reaction Chemistry & Engineering

A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates

(2015) Xavier Garrabou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereochemistry of enzymatic water addition to C = C bonds

(2015) Bi-Shuang Chen et al.   BIOTECHNOLOGY ADVANCES

Design of computational retrobiosynthesis tools for the design of de novo synthetic pathways

(2015) Noushin Hadadi et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Microscale technology and biocatalytic processes: opportunities and challenges for synthesis

(2015) Roland Wohlgemuth et al.   TRENDS IN BIOTECHNOLOGY

Systems Biocatalysis: An Artificial Metabolism for Interconversion of Functional Groups

(2015) D. Tessaro et al.   ACS Catalysis

Introducing an In Situ Capping Strategy in Systems Biocatalysis To Access 6-Aminohexanoic acid

(2014) Johann H. Sattler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Decarboxylation-An Emerging Reaction for Chemicals Production from Renewable Resources

(2014) Robert Kourist et al.   ChemCatChem

Combining the ‘two worlds’ of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media

(2014) Harald Gröger et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

One-step synthesis of 2-keto-3-deoxy-d-gluconate by biocatalytic dehydration of d-gluconate

(2014) Kohei Matsubara et al.   JOURNAL OF BIOTECHNOLOGY

Greener approach to efficient leather soaking process: role of enzymes and their synergistic effect

(2014) Jianzhong Ma et al.   JOURNAL OF CLEANER PRODUCTION

Enzyme-based biosilica and biocalcite: biomaterials for the future in regenerative medicine

(2014) Xiaohong Wang et al.   TRENDS IN BIOTECHNOLOGY

Biocatalytic asymmetric phosphorylation of mevalonate

(2014) R. Matsumi et al.   RSC Advances

CC Hydrolases for Biocatalysis

(2013) Elina Siirola et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Enzymatic Hydration of Hydroxystyrene Derivatives

(2013) Christiane Wuensch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic glycosylation of multivalent scaffolds

(2013) Pavla Bojarová et al.   CHEMICAL SOCIETY REVIEWS

Industrial use of immobilized enzymes

(2013) Robert DiCosimo et al.   CHEMICAL SOCIETY REVIEWS

CC bond formation using ThDP-dependent lyases

(2013) Michael Müller et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Fifty-five years of enzyme classification: advances and difficulties

(2013) Andrew G. McDonald et al.   FEBS Journal

Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future

(2013) Manfred T. Reetz   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

(2013) Robin Teufel et al.   NATURE

Multistep One-Pot Reactions Combining Biocatalysts and Chemical Catalysts for Asymmetric Synthesis

(2013) Carl A. Denard et al.   ACS Catalysis

Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance

(2012) K. C. Nicolaou et al.   CHEMICAL SOCIETY REVIEWS

Microbe–microbe interactions in mixed culture food fermentations

(2012) Eddy J Smid et al.   CURRENT OPINION IN BIOTECHNOLOGY

Application of state-of-art sequencing technologies to indigenous food fermentations

(2012) Sacha AFT van Hijum et al.   CURRENT OPINION IN BIOTECHNOLOGY

The use of enzymes in organic synthesis and the life sciences: perspectives from the Swiss Industrial Biocatalysis Consortium (SIBC)

(2012) Hans-Peter Meyer et al.   Catalysis Science & Technology

Enzymatic Total Synthesis of Defucogilvocarcin M and Its Implications for Gilvocarcin Biosynthesis

(2011) Pallab Pahari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic ketone reduction: A green and efficient access to enantiopure alcohols

(2011) Yan Ni et al.   BIOTECHNOLOGY ADVANCES

A retrosynthetic biology approach to metabolic pathway design for therapeutic production

(2011) Pablo Carbonell et al.   BMC Systems Biology

Investigating Mithramycin Deoxysugar Biosynthesis: Enzymatic Total Synthesis of TDP-D-Olivose

(2011) Guojun Wang et al.   CHEMBIOCHEM

Enzymatic reductions for the chemist

(2011) Frank Hollmann et al.   GREEN CHEMISTRY

Biocatalysis—key to sustainable industrial chemistry

(2010) Roland Wohlgemuth   CURRENT OPINION IN BIOTECHNOLOGY

High-Yield Biocatalytic Amination Reactions in Organic Synthesis

(2010) John Ward et al.   CURRENT ORGANIC CHEMISTRY

Enzymatic Total Synthesis of Rabelomycin, an Angucycline Group Antibiotic

(2010) Madan Kumar Kharel et al.   ORGANIC LETTERS

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

ω-Transaminases for the synthesis of non-racemic α-chiral primary amines

(2010) Dominik Koszelewski et al.   TRENDS IN BIOTECHNOLOGY

Applications of biotransformations and biocatalysis to complexity generation in organic synthesis

(2009) Tomas Hudlicky et al.   CHEMICAL SOCIETY REVIEWS

C2-Ketol elongation by transketolase-catalyzed asymmetric synthesis

(2009) Roland Wohlgemuth   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Enzymes, detergents and skin: facts and fantasies

(2008) D.A. Basketter et al.   BRITISH JOURNAL OF DERMATOLOGY

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

(2008) Shota Atsumi et al.   NATURE