A reductive aminase from Aspergillus oryzae

Direct Asymmetric Reductive Amination for the Synthesis of Chiral β-Arylamines

(2016) Haizhou Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalysed transannular C–H functionalization of alicyclic amines

(2016) Joseph J. Topczewski et al.   NATURE

A platform for the discovery of new macrolide antibiotics

(2016) Ian B. Seiple et al.   NATURE

Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines

(2016) Ioannis V. Pavlidis et al.   Nature Chemistry

Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis

(2016) Godwin A. Aleku et al.   ACS Catalysis

Biocatalytic Imine Reduction and Reductive Amination of Ketones

(2015) Joerg H. Schrittwieser et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis ofD- andL-Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process

(2015) Fabio Parmeggiani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing theS-Selective Reduction of the Imine Substrate 2-Methylpyrroline

(2015) Henry Man et al.   CHEMBIOCHEM

Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein-Sequence Space

(2015) Dennis Wetzl et al.   CHEMBIOCHEM

An (R)-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines

(2015) Shahed Hussain et al.   ChemCatChem

Imine Reductase-Catalyzed Intermolecular Reductive Amination of Aldehydes and Ketones

(2015) Philipp N. Scheller et al.   ChemCatChem

The Bacterial Ammonia Lyase EncP: A Tunable Biocatalyst for the Synthesis of Unnatural Amino Acids

(2015) Nicholas J. Weise et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Kinetic Resolution of Disubstituted Piperidines by Enantioselective Acylation: Synthetic Utility and Mechanistic Insights

(2015) Benedikt Wanner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

(2015) F. G. Mutti et al.   SCIENCE

Engineering of Amine Dehydrogenase for Asymmetric Reductive Amination of Ketone by Evolving Rhodococcus Phenylalanine Dehydrogenase

(2015) Li Juan Ye et al.   ACS Catalysis

TailoringD-Amino Acid Oxidase from the Pig Kidney toR-Stereoselective Amine Oxidase and its Use in the Deracemization of α-Methylbenzylamine

(2014) Kazuyuki Yasukawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases

(2014) Philipp N. Scheller et al.   CHEMBIOCHEM

Development of an R -Selective Amine Oxidase with Broad Substrate Specificity and High Enantioselectivity

(2014) Rachel S. Heath et al.   ChemCatChem

Direct Reductive Amination of Ketones: Structure and Activity ofS-Selective Imine Reductases fromStreptomyces

(2014) Tobias Huber et al.   ChemCatChem

Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis

(2014) Hannes Kohls et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Characterization of three novel enzymes with imine reductase activity

(2014) M. Gand et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Structure and Activity of NADPH-Dependent Reductase Q1EQE0 fromStreptomyces kanamyceticus, which Catalyses theR-Selective Reduction of an Imine Substrate

(2013) María Rodríguez-Mata et al.   CHEMBIOCHEM

Asymmetric Reduction of Cyclic Imines Catalyzed by a Whole-Cell Biocatalyst Containing an (S)-Imine Reductase

(2013) Friedemann Leipold et al.   ChemCatChem

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

(2013) Diego Ghislieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric synthesis of amines using tert-butanesulfinamide

(2013) Hai-Chao Xu et al.   Nature Protocols

Recent Developments of Cascade Reactions Involving ω-Transaminases

(2013) Robert C. Simon et al.   ACS Catalysis

Development of an Amine Dehydrogenase for Synthesis of Chiral Amines

(2012) Michael J. Abrahamson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A NADPH-dependent (S)-imine reductase (SIR) from Streptomyces sp. GF3546 for asymmetric synthesis of optically active amines: purification, characterization, gene cloning, and expression

(2012) Koichi Mitsukura et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

ω-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids

(2012) Sam Mathew et al.   ACS Catalysis

Purification and Characterization of a Novel (R)-Imine Reductase fromStreptomycessp. GF3587

(2011) Koichi MITSUKURA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Asymmetric Synthesis of (S)-2-Indolinecarboxylic Acid by Combining Biocatalysis and Homogeneous Catalysis

(2011) Ben de Lange et al.   ChemCatChem

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric synthesis of chiral cyclic amine from cyclic imine by bacterial whole-cell catalyst of enantioselective imine reductase

(2010) Koichi Mitsukura et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Utilizing simple biochemical measurements to predict lifetime output of biocatalysts in continuous isothermal processes

(2009) Thomas A. Rogers et al.   CHEMICAL ENGINEERING SCIENCE

Metal−Brønsted Acid Cooperative Catalysis for Asymmetric Reductive Amination

(2009) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY