- Home
- Publications
- Publication Search
- Publication Details
Title
Mitochondrial Mechanisms of Necroptosis in Liver Diseases
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 1, Pages 66
Publisher
MDPI AG
Online
2020-12-23
DOI
10.3390/ijms22010066
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MLKL contributes to Western diet-induced liver injury through inhibiting autophagy
- (2020) Xiaoqin Wu et al. Autophagy
- Inhibitory effects of JQ1 on listeria monocytogenes-induced acute liver injury by blocking BRD4/RIPK1 axis
- (2020) Zhao Qian et al. BIOMEDICINE & PHARMACOTHERAPY
- Targeting NUPR1 with the small compound ZZW-115 is an efficient strategy to treat hepatocellular carcinoma
- (2020) Wenjun Lan et al. CANCER LETTERS
- Mechanisms and pathogenesis underlying environmental chemical-induced necroptosis
- (2020) Mohammad-Reza Sepand et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- ROS-Mediated Necroptosis Is Involved in Iron Overload-Induced Osteoblastic Cell Death
- (2020) Qing Tian et al. Oxidative Medicine and Cellular Longevity
- Integrative analysis of hepatic metabolomic and transcriptomic data reveals potential mechanism of nonalcoholic steatohepatitis in high‐fat diet–fed mice
- (2020) Jinhua Wang et al. Journal of Diabetes
- Ferroptosis as a target for protection against cardiomyopathy
- (2019) Xuexian Fang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell death: a review of the major forms of apoptosis, necrosis and autophagy
- (2019) Mark S D’Arcy CELL BIOLOGY INTERNATIONAL
- The role of necroptosis in cancer biology and therapy
- (2019) Yitao Gong et al. Molecular Cancer
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- Collateral Damage: Necroptosis in the Development of Lung Injury
- (2019) Hilary Faust et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease
- (2019) Amine Majdi et al. JOURNAL OF HEPATOLOGY
- Mitochondria as multifaceted regulators of cell death
- (2019) Florian J. Bock et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Necroptosis signaling in liver diseases: An update
- (2019) Waqar Khalid Saeed et al. PHARMACOLOGICAL RESEARCH
- The potential role of necroptosis in inflammaging and aging
- (2019) Gordon H. Royce et al. GeroScience
- JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells
- (2019) K.A. Heslop et al. BIOCHEMICAL PHARMACOLOGY
- Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis
- (2018) Michael M. Gaschler et al. ACS Chemical Biology
- New Insights About Albumin and Liver Disease
- (2018) Joana R. Carvalho et al. Annals of Hepatology
- Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis
- (2018) Songfeng Chen et al. APOPTOSIS
- Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
- (2018) Nathalia M. de Vasconcelos et al. CELL DEATH AND DIFFERENTIATION
- Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis
- (2018) Qinrui Han et al. Journal of Translational Medicine
- RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis
- (2018) Zhentao Yang et al. NATURE CELL BIOLOGY
- Temporal Pattern and Crosstalk of Necroptosis Markers with Autophagy and Apoptosis Associated Proteins in Ischemic Hippocampus
- (2018) Fari Ryan et al. NEUROTOXICITY RESEARCH
- PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction
- (2018) Yun Sun Park et al. TOXICOLOGY LETTERS
- Mitochondrial permeability regulates cardiac endothelial cell necroptosis and cardiac allograft rejection
- (2018) Ingrid Gan et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Necroptosis microenvironment directs lineage commitment in liver cancer
- (2018) Marco Seehawer et al. NATURE
- Apoptosis and necroptosis in the liver: a matter of life and death
- (2018) Robert F. Schwabe et al. Nature Reviews Gastroenterology & Hepatology
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease
- (2018) Ignazio Grattagliano et al. BIOCHEMICAL PHARMACOLOGY
- Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells
- (2017) Wen Sun et al. FREE RADICAL BIOLOGY AND MEDICINE
- The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation
- (2017) Vangelis Kondylis et al. IMMUNOLOGICAL REVIEWS
- Necroptosis Resumes Apoptosis in Hippocampus but Not in Frontal Cortex
- (2017) Sara Nikseresht et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Treatment options for alcoholic and non-alcoholic fatty liver disease: A review
- (2017) Sukhpreet Singh et al. WORLD JOURNAL OF GASTROENTEROLOGY
- RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
- (2017) Yingying Zhang et al. Nature Communications
- S -nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase
- (2016) Salvatore Rizza et al. CANCER RESEARCH
- Recent Advancements in Diagnosis and Therapy of Liver Cirrhosis
- (2016) Roberto Giulio Romanelli et al. CURRENT DRUG TARGETS
- Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
- (2016) Katelyn L. O'Neill et al. GENES & DEVELOPMENT
- PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury
- (2016) Gui-Wei He et al. GUT
- Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury
- (2016) Sanjoy Roychowdhury et al. HEPATOLOGY
- c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src
- (2016) Sanda Win et al. HEPATOLOGY
- A murder mystery in the liver: who done it and how?
- (2016) Lily Dara et al. JOURNAL OF CLINICAL INVESTIGATION
- The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis
- (2016) Claudia Günther et al. JOURNAL OF CLINICAL INVESTIGATION
- Prevention of Cyclophilin D-Mediated mPTP Opening Using Cyclosporine-A Alleviates the Elevation of Necroptosis, Autophagy and Apoptosis-Related Markers Following Global Cerebral Ischemia-Reperfusion
- (2016) Farinoosh Fakharnia et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis
- (2016) Giovanni Quarato et al. MOLECULAR CELL
- Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance
- (2016) Jessie Pécot et al. Cell Reports
- The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis
- (2016) Yue-Qi Wang et al. Frontiers in Aging Neuroscience
- Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis
- (2016) Wei Lu et al. PLoS One
- Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis
- (2015) Lily Dara et al. HEPATOLOGY
- The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages
- (2015) Kenta Moriwaki et al. JOURNAL OF IMMUNOLOGY
- The diverse role of RIP kinases in necroptosis and inflammation
- (2015) John Silke et al. NATURE IMMUNOLOGY
- Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death
- (2015) B Schenk et al. ONCOGENE
- The global burden of liver disease: The major impact of China
- (2014) Fu-Sheng Wang et al. HEPATOLOGY
- A Conserved Motif Mediates both Multimer Formation and Allosteric Activation of Phosphoglycerate Mutase 5
- (2014) Jordan M. Wilkins et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
- (2014) Joanne M. Hildebrand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of receptor interacting protein (RIP)1 on apoptosis-inducing factor-mediated necroptosis during acetaminophen-evoked acute liver failure in mice
- (2014) Ye-Fa Zhang et al. TOXICOLOGY LETTERS
- Role of Bax/Bcl-2 family members in green tea polyphenol induced necroptosis of p53-deficient Hep3B cells
- (2014) Weiping Lin et al. TUMOR BIOLOGY
- Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
- (2014) Q Remijsen et al. Cell Death & Disease
- Necroptosis: is there a role for mitochondria?
- (2014) Kurt D. Marshall et al. Frontiers in Physiology
- TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species
- (2013) Francisco J. Roca et al. CELL
- Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice
- (2013) Anup Ramachandran et al. HEPATOLOGY
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
- (2013) A. Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oxidative stress and hepatitis C virus
- (2013) Usman Paracha et al. Virology Journal
- Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis
- (2013) Stephen W.G. Tait et al. Cell Reports
- Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
- (2013) Jason Karch et al. eLife
- Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members
- (2012) Denise Tischner et al. APOPTOSIS
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways
- (2012) Zhigao Wang et al. CELL
- Mitochondrial Control of Cellular Life, Stress, and Death
- (2012) Lorenzo Galluzzi et al. CIRCULATION RESEARCH
- Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
- (2012) Sanjoy Roychowdhury et al. HEPATOLOGY
- Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5
- (2012) Shiori Sekine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator
- (2012) Min Zhuang et al. MOLECULAR CELL
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
- (2011) L Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Mitochondria in Chronic Liver Disease
- (2011) Ignazio Grattagliano et al. CURRENT DRUG TARGETS
- Central role of mitochondria in drug-induced liver injury
- (2011) Dominique Pessayre et al. DRUG METABOLISM REVIEWS
- Beginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways
- (2011) Kodi S. Ravichandran IMMUNITY
- Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis
- (2011) K. M. Irrinki et al. MOLECULAR AND CELLULAR BIOLOGY
- A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria
- (2011) Fabien Llambi et al. MOLECULAR CELL
- The Cardiac Mitochondrion: Nexus of Stress
- (2010) Christopher P. Baines Annual Review of Physiology
- cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
- (2010) N Vanlangenakker et al. CELL DEATH AND DIFFERENTIATION
- Tumor necrosis factor-mediated cell death: to break or to burst, that’s the question
- (2010) Franky Van Herreweghe et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Targeting Mitochondria: A New Promising Approach for the Treatment of Liver Diseases
- (2010) G. Serviddio et al. CURRENT MEDICINAL CHEMISTRY
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The molecular regulation of programmed necrotic cell injury
- (2010) David Moquin et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila
- (2010) Yuzuru Imai et al. PLoS Genetics
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- Hepatic Mitochondrial DNA Depletion after an Alcohol Binge in Mice: Probable Role of Peroxynitrite and Modulation by Manganese Superoxide Dismutase
- (2009) I. Larosche et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1
- (2009) K. Takeda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
- (2009) D.-W. Zhang et al. SCIENCE
- Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
- (2008) Junichi Hitomi et al. CELL
- PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
- (2008) Shih-Ching Lo et al. EXPERIMENTAL CELL RESEARCH
- Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates
- (2008) Isabelle Larosche et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started