Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5
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Title
Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 41, Pages 34635-34645
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-08-23
DOI
10.1074/jbc.m112.357509
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Note: Only part of the references are listed.- The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways
- (2012) Zhigao Wang et al. CELL
- Prevention of Apoptosis by Mitochondrial Phosphatase PGAM5 in the Mushroom Body Is Crucial for Heat Shock Resistance in Drosophila melanogaster
- (2012) Yosuke Ishida et al. PLoS One
- Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease
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- Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network
- (2010) Atsushi Tanaka FEBS LETTERS
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila
- (2010) Yuzuru Imai et al. PLoS Genetics
- Parkin-induced mitophagy in the pathogenesis of Parkinson disease
- (2009) Derek Narendra et al. Autophagy
- Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1
- (2009) Sarah Ehses et al. JOURNAL OF CELL BIOLOGY
- Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
- (2009) Brian Head et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1
- (2009) K. Takeda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
- (2008) A. J. Whitworth et al. Disease Models & Mechanisms
- PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
- (2008) Shih-Ching Lo et al. EXPERIMENTAL CELL RESEARCH
- Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons
- (2008) Jyh-Rong Chao et al. NATURE
- Human Herpesvirus-6 Induces MVB Formation, and Virus Egress Occurs by an Exosomal Release Pathway
- (2008) Yasuko Mori et al. TRAFFIC
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