c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity

(2015) Sanda Win et al.   JOURNAL OF HEPATOLOGY

Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury

(2015) Yuchao Xie et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In Vitro Assays of Mitochondrial Function/Dysfunction

(2014) T A Than et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Dok1 and Dok2 proteins regulate natural killer cell development and function

(2014) Javier Celis‐Gutierrez et al.   EMBO JOURNAL

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

(2014) S Win et al.   Cell Death & Disease

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria

(2013) Derick Han et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components

(2012) Masato Ogura et al.   BIOCHEMICAL JOURNAL

A Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches

(2012) Ekihiro Seki et al.   GASTROENTEROLOGY

Suppression of Hepatocyte Proliferation by Hepatocyte Nuclear Factor 4α in Adult Mice

(2012) Jessica A. Bonzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blocking c-Jun N-terminal Kinase (JNK) Translocation to the Mitochondria Prevents 6-Hydroxydopamine-induced Toxicityin Vitroandin Vivo

(2012) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of JNK Mitochondrial Localization and Signaling Is Protective against Ischemia/Reperfusion Injury in Rats

(2012) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Inhibition of Mitochondrial JNK Signaling Achieved Using Peptide Mimicry of the Sab Kinase Interacting Motif-1 (KIM1)

(2011) Jeremy W. Chambers et al.   ACS Chemical Biology

Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation

(2011) Ryan G. Holzer et al.   CELL

c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice

(2011) Sanda Win et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial c-Jun N-terminal Kinase (JNK) Signaling Initiates Physiological Changes Resulting in Amplification of Reactive Oxygen Species Generation

(2011) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Who pulls the trigger: JNK activation in liver lipotoxicity?

(2011) Samar H. Ibrahim et al.   JOURNAL OF HEPATOLOGY

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury

(2010) Anup Ramachandran et al.   FREE RADICAL RESEARCH

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity

(2010) Chieko Saito et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

JNK regulation of hepatic manifestations of the metabolic syndrome

(2010) Mark J. Czaja   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Redox signaling and protein phosphorylation in mitochondria: progress and prospects

(2009) D. Brian Foster et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis

(2009) C. Morel et al.   MOLECULAR AND CELLULAR BIOLOGY

Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation

(2008) Hayato Nakagawa et al.   GASTROENTEROLOGY

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

(2008) Naoko Hanawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation

(2008) Elena Tibaldi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE