Pathophysiology of Type 2 Diabetes Mellitus

Mitochondrial ROS and Mitophagy: A Complex and Nuanced Relationship

(2020) James H. Schofield et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms of insulin resistance related to white, beige, and brown adipocytes

(2020) Michael P. Czech   Molecular Metabolism

Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet

(2019) Domenico Sergi et al.   Frontiers in Physiology

The Beta Cell in Type 2 Diabetes

(2019) Ashley A. Christensen et al.   Current Diabetes Reports

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes

(2019) Jenny E. Kanter et al.   JOURNAL OF CLINICAL INVESTIGATION

Relevance of Leptin and Other Adipokines in Obesity-Associated Cardiovascular Risk

(2019) Manuel F. Landecho et al.   Nutrients

Omentin-1 attenuates lipopolysaccharide (LPS)-induced U937 macrophages activation by inhibiting the TLR4/MyD88/NF-κB signaling

(2019) Jinzhong Wang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The integrative biology of type 2 diabetes

(2019) Michael Roden et al.   NATURE

Focusing on mitochondrial form and function

(2018)   NATURE CELL BIOLOGY

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

(2018) Patrik Rorsman et al.   PHYSIOLOGICAL REVIEWS

Risk factors for type 2 diabetes mellitus: An exposure-wide umbrella review of meta-analyses

(2018) Vanesa Bellou et al.   PLoS One

Altered Gut Microbiota in Type 2 Diabetes: Just a Coincidence?

(2018) Antonio Sircana et al.   Current Diabetes Reports

Epigenetics and Epigenomics: Implications for Diabetes and Obesity

(2018) Evan D. Rosen et al.   DIABETES

MicroRNAs in islet hormone secretion

(2018) Jonathan L. S. Esguerra et al.   DIABETES OBESITY & METABOLISM

Biosynthesis, structure, and folding of the insulin precursor protein

(2018) Ming Liu et al.   DIABETES OBESITY & METABOLISM

3. Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2019

(2018)   DIABETES CARE

The many secret lives of adipocytes: implications for diabetes

(2018) Philipp E. Scherer   DIABETOLOGIA

Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell

(2018) Wataru R. Yamamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel

(2017) Brian A. Ference et al.   EUROPEAN HEART JOURNAL

Skeletal muscle inflammation and insulin resistance in obesity

(2017) Huaizhu Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Type 2 diabetes

(2017) Sudesna Chatterjee et al.   LANCET

Insulin action and resistance in obesity and type 2 diabetes

(2017) Michael P Czech   NATURE MEDICINE

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Oxidative stress, protein damage and repair in bacteria

(2017) Benjamin Ezraty et al.   NATURE REVIEWS MICROBIOLOGY

Omentin treatment of epicardial fat improves its anti-inflammatory activity and paracrine benefit on smooth muscle cells

(2017) Ángel Fernández-Trasancos et al.   Obesity

Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet

(2017) P.E. Bunney et al.   PHYSIOLOGY & BEHAVIOR

Unraveling the Regulation of Hepatic Metabolism by Insulin

(2017) Paul M. Titchenell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Gut Microbiota Dysbiosis Drives and Implies Novel Therapeutic Strategies for Diabetes Mellitus and Related Metabolic Diseases

(2017) Xuan Li et al.   Frontiers in Immunology

The dynamic plasticity of insulin production in β-cells

(2017) Brandon B. Boland et al.   Molecular Metabolism

MicroRNAs as stress regulators in pancreatic beta cells and diabetes

(2017) Mary P. LaPierre et al.   Molecular Metabolism

Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell

(2017) Jones K. Ofori et al.   Scientific Reports

The Effects of Insulin Resistance on Individual Tissues: An Application of a Mathematical Model of Metabolism in Humans

(2016) Taliesin Pearson et al.   BULLETIN OF MATHEMATICAL BIOLOGY

The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell–Centric Classification Schema

(2016) Stanley S. Schwartz et al.   DIABETES CARE

Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study

(2016) Nathan D. Wong et al.   DIABETES CARE

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

(2016) Philip L.S.M. Gordts et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulatory Role of Omentin-1 in Inflammation: Cytokines and Dietary Intake

(2016) Fateme Zabetian-Targhi et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

(2016)   LANCET

Activation of PKA and Epac proteins by cyclic AMP depletes intracellular calcium stores and reduces calcium availability for vasoconstriction

(2016) Andrea Cuíñas et al.   LIFE SCIENCES

The genetic architecture of type 2 diabetes

(2016) Christian Fuchsberger et al.   NATURE

Type 2 diabetes: genetic data sharing to advance complex disease research

(2016) Jason Flannick et al.   NATURE REVIEWS GENETICS

Epigenetic changes in diabetes

(2016) Rami Al-Haddad et al.   NEUROSCIENCE LETTERS

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Approach to diabetes management in patients with CVD

(2016) Sanam Lathief et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Triglyceride-Rich Lipoproteins and Remnants: Targets for Therapy?

(2016) Geesje M. Dallinga-Thie et al.   Current Cardiology Reports

New markers of insulin resistance in polycystic ovary syndrome

(2016) K. Polak et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses

(2015) Huifang Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Insulin secretion from beta cells within intact islets: Location matters

(2015) Oanh Hoang Do et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Pathophysiology of diabetic dyslipidaemia: where are we?

(2015) Bruno Vergès   DIABETOLOGIA

Adiponectin-Mediated Antilipotoxic Effects in Regenerating Pancreatic Islets

(2015) Risheng Ye et al.   ENDOCRINOLOGY

miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development

(2015) Mathieu Latreille et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

(2015) Emily D. Montal et al.   MOLECULAR CELL

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes

(2015) Cong Tang et al.   NATURE MEDICINE

A giant molecular proton pump: structure and mechanism of respiratory complex I

(2015) Leonid A. Sazanov   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Role of Microbial Amino Acid Metabolism in Host Metabolism

(2015) Evelien Neis et al.   Nutrients

The Role of Vaspin in the Development of Metabolic and Glucose Tolerance Disorders and Atherosclerosis

(2015) Rumyana Dimova et al.   Biomed Research International

Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management

(2015) Naveed Sattar et al.   Lancet Diabetes & Endocrinology

NETosis is induced by high glucose and associated with type 2 diabetes

(2014) Lisa Menegazzo et al.   ACTA DIABETOLOGICA

Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease

(2014) Ron C. Hoogeveen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis

(2014) Kyoung-Jin Oh et al.   BMB Reports

Postprandial hypertriglyceridemia as a coronary risk factor

(2014) Jan Borén et al.   CLINICA CHIMICA ACTA

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

(2014) Philippe A. Halban et al.   DIABETES CARE

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Epigenetic mechanisms in diabetic complications and metabolic memory

(2014) Marpadga A. Reddy et al.   DIABETOLOGIA

Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

(2014) Niels Grarup et al.   DIABETOLOGIA

Gut microbiome and the risk factors in central nervous system autoimmunity

(2014) Javier Ochoa-Repáraz et al.   FEBS LETTERS

Molecular Mechanisms for the Regulation of Insulin-Stimulated Glucose Uptake by Small Guanosine Triphosphatases in Skeletal Muscle and Adipocytes

(2014) Takaya Satoh   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

Triglycerides and cardiovascular disease

(2014) Børge G Nordestgaard et al.   LANCET

Insulin resistance and hyperglycaemia in cardiovascular disease development

(2014) Markku Laakso et al.   Nature Reviews Endocrinology

High-Lard and High-Fish-Oil Diets Differ in Their Effects on Function and Dynamic Behaviour of Rat Hepatic Mitochondria

(2014) Lillà Lionetti et al.   PLoS One

Association of Vaspin with Metabolic Syndrome: The Pivotal Role of Insulin Resistance

(2014) Alireza Esteghamati et al.   Diabetes & Metabolism Journal

Lifestyle Interventions for Patients With and at Risk for Type 2 Diabetes

(2013) Elizabeth Sumamo Schellenberg et al.   ANNALS OF INTERNAL MEDICINE

State of the art paper Biochemistry of adipose tissue: an endocrine organ

(2013) Marisa Coelho et al.   Archives of Medical Science

Endothelial dysfunction — A major mediator of diabetic vascular disease

(2013) Cristina M. Sena et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Molecular Mechanisms Linking Diabetes to the Accelerated Development of Atherosclerosis

(2013) Melec G. Zeadin et al.   Canadian Journal of Diabetes

Potential role of Toll-like receptors in programming of vascular dysfunction

(2013) Jennifer A. Thompson et al.   CLINICAL SCIENCE

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

(2013) Antigone S. Dimas et al.   DIABETES

Gene-Environment and Gene-Treatment Interactions in Type 2 Diabetes: Progress, pitfalls, and prospects

(2013) P. W. Franks et al.   DIABETES CARE

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I

(2013) Francesco Paneni et al.   EUROPEAN HEART JOURNAL

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation

(2013) Manjunath B. Joshi et al.   FEBS LETTERS

Circulating Irisin in Relation to Insulin Resistance and the Metabolic Syndrome

(2013) Kyung Hee Park et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity, adiposity, and dyslipidemia: A consensus statement from the National Lipid Association

(2013) Harold E. Bays et al.   Journal of Clinical Lipidology

High-density lipoproteins: A consensus statement from the National Lipid Association

(2013) Peter P. Toth et al.   Journal of Clinical Lipidology

Relationship of Lipoproteins to Cardiovascular Events

(2013) John R. Guyton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nod-Like Receptor Protein 1 Inflammasome Mediates Neuron Injury under High Glucose

(2013) Xian-Fang Meng et al.   MOLECULAR NEUROBIOLOGY

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

The regulation of ApoB metabolism by insulin

(2013) Mary E. Haas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Beta Cell Dysfunction and Insulin Resistance

(2013) Marlon E. Cerf   Frontiers in Endocrinology

Metabolic inflammation: Connecting obesity and insulin resistance

(2012) Nassim Dali-Youcef et al.   ANNALS OF MEDICINE

Physical activity in obesity and metabolic syndrome

(2012) Barbara Strasser   Annals of the New York Academy of Sciences

Selective Hepatic Insulin Resistance, VLDL Overproduction, and Hypertriglyceridemia

(2012) Janet D. Sparks et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammation in Atherosclerosis

(2012) Peter Libby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Insulin Resistance and Coronary Heart Disease in Nondiabetic Individuals

(2012) Gerald Reaven   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitophagy: mechanisms, pathophysiological roles, and analysis

(2012) Wen-Xing Ding et al.   BIOLOGICAL CHEMISTRY

Adipokines and the cardiovascular system: mechanisms mediating health and disease

(2012) Josette M. Northcott et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Heritable Transmission of Diabetic Metabolic Memory in Zebrafish Correlates With DNA Hypomethylation and Aberrant Gene Expression

(2012) A. S. Olsen et al.   DIABETES

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

Elevated Rates of Diabetes in Pacific Islanders and Asian Subgroups: The Diabetes Study of Northern California (DISTANCE)

(2012) A. J. Karter et al.   DIABETES CARE

Obesity and Metabolic Syndrome: An Inflammatory Condition

(2012) E. Scarpellini et al.   DIGESTIVE DISEASES

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

(2012) Pedro M Quirós et al.   EMBO JOURNAL

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

(2012) Amy R. Johnson et al.   IMMUNOLOGICAL REVIEWS

Increased DNA Methylation and Decreased Expression ofPDX-1in Pancreatic Islets from Patients with Type 2 Diabetes

(2012) Beatrice T. Yang et al.   MOLECULAR ENDOCRINOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Insulin Resistance and Risk of Incident Cardiovascular Events in Adults without Diabetes: Meta-Analysis

(2012) Karin B. Gast et al.   PLoS One

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

(2012) D. Sebastian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging challenge in diabetes: The “metabolic memory”

(2012) Antonio Ceriello   VASCULAR PHARMACOLOGY

Ageing of the human metaorganism: the microbial counterpart

(2011) Elena Biagi et al.   AGE

Mitophagy: A Complex Mechanism of Mitochondrial Removal

(2011) Ivana Novak   ANTIOXIDANTS & REDOX SIGNALING

Vascular Effects of Novel Adipocytokines: Focus on Vascular Contractility and Inflammatory Responses

(2011) Hideyuki Yamawaki   BIOLOGICAL & PHARMACEUTICAL BULLETIN

New adipokines vaspin and omentin. Circulating levels and gene expression in adipose tissue from morbidly obese women

(2011) Teresa Auguet et al.   BMC Medical Genetics

Epigenetic mechanisms in diabetic vascular complications

(2011) M. A. Reddy et al.   CARDIOVASCULAR RESEARCH

Insulin Resistance, Hyperglycemia, and Atherosclerosis

(2011) Karin E. Bornfeldt et al.   Cell Metabolism

Adipose Tissue ATP Binding Cassette Transporter A1 Contributes to High-Density Lipoprotein Biogenesis In Vivo

(2011) Soonkyu Chung et al.   CIRCULATION

Adipose Modulation of High-Density Lipoprotein Cholesterol

(2011) Fiona C. McGillicuddy et al.   CIRCULATION

Plasma vaspin concentrations are elevated in metabolic syndrome in men and are correlated with coronary atherosclerosis in women

(2011) Sung Hee Choi et al.   CLINICAL ENDOCRINOLOGY

Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1  Transcription in Human Adipose Tissue

(2011) T. B. Koenen et al.   DIABETES

Validation of Insulin Sensitivity and Secretion Indices Derived from the Liquid Meal Tolerance Test

(2011) Kevin C. Maki et al.   Diabetes Technology & Therapeutics

Macrovascular angiopathy in children and adolescents with type 1 diabetes

(2011) Cosimo Giannini et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

(2011) M. John Chapman et al.   EUROPEAN HEART JOURNAL

Molecular Mechanism for Adiponectin-dependent M2 Macrophage Polarization

(2011) Palash Mandal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of insulin secretion and the clinical implications for obesity and diabetes

(2011) Susumu Seino et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle

(2011) H.-F. Jheng et al.   MOLECULAR AND CELLULAR BIOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

(2011) Mohamad Navab et al.   Nature Reviews Cardiology

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phagocytic Activity Is Impaired in Type 2 Diabetes Mellitus and Increases after Metabolic Improvement

(2011) Albert Lecube et al.   PLoS One

Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance

(2011) Sung Hee Choi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of insulin secretion and reactive oxygen species production by free fatty acids in pancreatic islets

(2011) Maria Fernanda Graciano et al.   Islets

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

Carotid intima media thickness is associated with plasma adiponectin but not with the leptin:adiponectin ratio independently of metabolic syndrome

(2010) Robin P.F. Dullaart et al.   ATHEROSCLEROSIS

Abnormal hepatic apolipoprotein B metabolism in type 2 diabetes

(2010) Bruno Vergès   ATHEROSCLEROSIS

MicroRNAs: Synthesis, mechanism, function, and recent clinical trials

(2010) Fazli Wahid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Stable transmission of reversible modifications: maintenance of epigenetic information through the cell cycle

(2010) V. A. Blomen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Adipocyte Modulation of High-Density Lipoprotein Cholesterol

(2010) YuZhen Zhang et al.   CIRCULATION

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Changes of serum omentin-1 levels in normal subjects and in patients with impaired glucose regulation and with newly diagnosed and untreated type 2 diabetes

(2010) Hong-Yan Pan et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Pathogenesis of Insulin Resistance in Skeletal Muscle

(2010) Muhammad A. Abdul-Ghani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

(2010) The Emerging Risk Factors Collaboration   LANCET

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genomics, Type 2 Diabetes, and Obesity

(2010) Mark I. McCarthy   NEW ENGLAND JOURNAL OF MEDICINE

Advanced Glycation end Products, Oxidative Stress and Diabetic Nephropathy

(2010) Sho-ichi Yamagishi et al.   Oxidative Medicine and Cellular Longevity

DNA methylation and methyl-CpG binding proteins: developmental requirements and function

(2009) Ozren Bogdanović et al.   CHROMOSOMA

Hepatic insulin resistance, metabolic syndrome and cardiovascular disease

(2009) Reza Meshkani et al.   CLINICAL BIOCHEMISTRY

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

(2009) D. Brasacchio et al.   DIABETES

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

Impaired serum capacity to induce cholesterol efflux is associated with endothelial dysfunction in type 2 diabetes mellitus

(2009) Huali Zhou et al.   Diabetes & Vascular Disease Research

Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study

(2009) D. Dabelea et al.   DIABETES CARE

Is Hyperglycemia a Causal Factor in Cardiovascular Disease?: Does proving this relationship really matter? Yes

(2009) J. A. Davidson et al.   DIABETES CARE

Type 1 and Type 2 Diabetes in Asian and Pacific Islander U.S. Youth: The SEARCH for Diabetes in Youth Study

(2009) L. L. Liu et al.   DIABETES CARE

The complexities of microRNA regulation: mirandering around the rules

(2009) Kimberly Breving et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cytokine and Cytokine-Like Inflammation Markers, Endothelial Dysfunction, and Imbalanced Coagulation in Development of Diabetes and Its Complications

(2009) Ronald B. Goldberg   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

(2008) Alexander Laatsch et al.   ATHEROSCLEROSIS

Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity

(2008) Wineke Bakker et al.   CELL AND TISSUE RESEARCH

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Omentin-1, a Novel Adipokine, Is Decreased in Overweight Insulin-Resistant Women With Polycystic Ovary Syndrome: Ex Vivo and In Vivo Regulation of Omentin-1 by Insulin and Glucose

(2008) B. K. Tan et al.   DIABETES

The “Metabolic Memory”: Is More Than Just Tight Glucose Control Necessary to Prevent Diabetic Complications?

(2008) Antonio Ceriello et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis

(2008)   LANCET

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE