Triglyceride-Rich Lipoproteins and Remnants: Targets for Therapy?

Multiple microRNA regulation of lipoprotein lipase gene abolished by 3′UTR polymorphisms in a triglyceride-lowering haplotype harboring p.Ser474Ter

(2016) Cyrielle Caussy et al.   ATHEROSCLEROSIS

Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal ObesitySignificance

(2015) Jan Borén et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

New insights into the pathophysiology of dyslipidemia in type 2 diabetes

(2015) Marja-Riitta Taskinen et al.   ATHEROSCLEROSIS

A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis

(2015) Susan M. Armstrong et al.   CARDIOVASCULAR RESEARCH

Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis RegressionNovelty and Significance

(2015) Emil D. Bartels et al.   CIRCULATION RESEARCH

The crucial roles of apolipoproteins E and C-III in apoB lipoprotein metabolism in normolipidemia and hypertriglyceridemia

(2015) Frank M. Sacks   CURRENT OPINION IN LIPIDOLOGY

Hypertriglyceridemia in the Genomic Era: A New Paradigm

(2015) Gary F. Lewis et al.   ENDOCRINE REVIEWS

A Pressure-dependent Model for the Regulation of Lipoprotein Lipase by Apolipoprotein C-II

(2015) Nathan L. Meyers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiopoietin-like 4 Modifies the Interactions between Lipoprotein Lipase and Its Endothelial Cell Transporter GPIHBP1

(2015) Xun Chi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin

(2015) P. A. Nidhina Haridas et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association of APOC3  Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis

(2015) Pradeep Natarajan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Apolipoprotein C-III: From Pathophysiology to Pharmacology

(2015) Giuseppe Danilo Norata et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

APOC3, Coronary Disease, and Complexities of Mendelian Randomization

(2014) Jonathan C. Cohen et al.   Cell Metabolism

The GPIHBP1–LPL Complex Is Responsible for the Margination of Triglyceride-Rich Lipoproteins in Capillaries

(2014) Chris N. Goulbourne et al.   Cell Metabolism

Rare Variant APOC3 R19X Is Associated With Cardio-Protective Profiles in a Diverse Population-Based Survey as Part of the Epidemiologic Architecture for Genes Linked to Environment Study

(2014) D. C. Crawford et al.   Circulation-Cardiovascular Genetics

Postprandial hypertriglyceridemia as a coronary risk factor

(2014) Jan Borén et al.   CLINICA CHIMICA ACTA

Intestinal lipid absorption and lipoprotein formation

(2014) M. Mahmood Hussain   CURRENT OPINION IN LIPIDOLOGY

Mendelian randomization of blood lipids for coronary heart disease

(2014) Michael V. Holmes et al.   EUROPEAN HEART JOURNAL

Triglycerides and cardiovascular disease

(2014) Børge G Nordestgaard et al.   LANCET

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

(2014) Ron Do et al.   NATURE

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

(2014) Anders Berg Jørgensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting APOC3 in the Familial Chylomicronemia Syndrome

(2014) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

(2013) Mark J. Graham et al.   CIRCULATION RESEARCH

Apolipoproteins C-I and C-III Inhibit Lipoprotein Lipase Activity by Displacement of the Enzyme from Lipid Droplets

(2013) Mikael Larsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiopoietin-like Protein 4 Inhibition of Lipoprotein Lipase

(2013) Michael J. Lafferty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ectopic lipid storage and insulin resistance: a harmful relationship

(2013) J. Borén et al.   JOURNAL OF INTERNAL MEDICINE

Prevalence and Trends of Metabolic Syndrome in the Adult U.S. Population, 1999–2010

(2013) Hiram Beltrán-Sánchez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Common variants associated with plasma triglycerides and risk for coronary artery disease

(2013) Ron Do et al.   NATURE GENETICS

Lipoprotein Metabolism, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

(2013) Edward Fisher et al.   SEMINARS IN LIVER DISEASE

The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

(2013) Robert A Hegele et al.   Lancet Diabetes & Endocrinology

Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity

(2012) Martin Adiels et al.   ATHEROSCLEROSIS

Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family

(2012) Zhiyao Fu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Influence of apolipoprotein A-V on the metabolic fate of triacylglycerol

(2012) Vineeta Sharma et al.   CURRENT OPINION IN LIPIDOLOGY

Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction

(2012) Anders Berg Jørgensen et al.   EUROPEAN HEART JOURNAL

Mutations inLPL,APOC2,APOA5,GPIHBP1andLMF1in patients with severe hypertriglyceridaemia

(2012) R. P. Surendran et al.   JOURNAL OF INTERNAL MEDICINE

Remnant Cholesterol as a Causal Risk Factor for Ischemic Heart Disease

(2012) Anette Varbo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A review of the role of apolipoprotein C-II in lipoprotein metabolism and cardiovascular disease

(2012) Anastazia A. Kei et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Atypical angiopoietin-like protein that regulates ANGPTL3

(2012) F. Quagliarini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual Metabolic Defects Are Required to Produce Hypertriglyceridemia in Obese Subjects

(2011) Marja-Riitta Taskinen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apolipoprotein CIII

(2011) Henry N. Ginsberg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis

(2011) Jiyun Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heterozygosity for a Loss-of-Function Mutation in GALNT2 Improves Plasma Triglyceride Clearance in Man

(2011) Adriaan G. Holleboom et al.   Cell Metabolism

Genetic bases of hypertriglyceridemic phenotypes

(2011) Christopher T. Johansen et al.   CURRENT OPINION IN LIPIDOLOGY

ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)

(2011) et al.   EUROPEAN HEART JOURNAL

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

(2011) M. John Chapman et al.   EUROPEAN HEART JOURNAL

Retention of atherogenic lipoproteins in the artery wall and its role in atherogenesis

(2011) P. Fogelstrand et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Intravenous Injection of Apolipoprotein A-V Reconstituted High-Density Lipoprotein Decreases Hypertriglyceridemia in apoav −/− Mice and Requires Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein–Binding Protein 1

(2010) Xiao Shu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Binding Preferences for GPIHBP1, a Glycosylphosphatidylinositol-Anchored Protein of Capillary Endothelial Cells

(2010) Peter Gin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

(2010) Brandon S.J. Davies et al.   Cell Metabolism

Nonfasting triglycerides and risk of cardiovascular death in men and women from the Norwegian Counties Study

(2010) Anja S. Lindman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

(2010)   LANCET

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

Exome Sequencing,ANGPTL3Mutations, and Familial Combined Hypolipidemia

(2010) Kiran Musunuru et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lipoprotein lipase: from gene to obesity

(2009) Hong Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolism of Very-Low-Density Lipoprotein and Low-Density Lipoprotein Containing Apolipoprotein C-III and Not Other Small Apolipoproteins

(2009) Carlos O. Mendivil et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

FoxO1 and hepatic lipid metabolism

(2009) Janet D Sparks et al.   CURRENT OPINION IN LIPIDOLOGY

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

(2009) M. J. Chapman et al.   EUROPEAN HEART JOURNAL

Role of caveolin-1 in the regulation of lipoprotein metabolism

(2008) Philippe G. Frank et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Overproduction of Very Low–Density Lipoproteins Is the Hallmark of the Dyslipidemia in the Metabolic Syndrome

(2008) Martin Adiels et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population

(2008) Jacob J. Freiberg   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

(2008) T. I. Pollin et al.   SCIENCE

The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism

(2008) Tai Hato et al.   TRENDS IN CARDIOVASCULAR MEDICINE